Zobrazeno 1 - 10
of 113
pro vyhledávání: '"P.G. Watanabe"'
Autor:
William Stansley, P.G. Watanabe, Molly Whitworth, Christine M. Bunck, Crystal J. Driver, Thomas E. Lacher, Frederick A. Leighton, Bernard Daniel, Christian E. Grue, Ronald J. Kendall
Publikováno v:
Environmental Toxicology and Chemistry. 15:4-20
There is increasing concern that birds in terrestrial ecosystems may be exposed to spent lead shot. Evidence exists that upland birds, particularly mourning doves (Zenaida macroura), ingest spent lead shot and that raptors ingest lead shot by consumi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd69a1f695aec797d89434fe3849352b
https://doi.org/10.1002/etc.5620150103
https://doi.org/10.1002/etc.5620150103
Publikováno v:
Toxicology and Applied Pharmacology. 44:581-591
The toxicity of many chemicals results from biotransformation products formed from the chemical rather than from the chemical per se. In such cases, the incremental response may become diminishingly smaller with increasing dose or exposure because ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c3e8517050974dfc10eb5d73a8705e
https://doi.org/10.1016/0041-008x(78)90266-1
https://doi.org/10.1016/0041-008x(78)90266-1
Publikováno v:
Biochemistry. 18:5177-5182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525f7a99e6c95292a7f6c0b85591e5d9
https://doi.org/10.1021/bi00590a023
https://doi.org/10.1021/bi00590a023
Autor:
P.G. Watanabe, R.P. Sharma
Publikováno v:
Journal of Comparative Pathology. 85:373-381
A mixed cell nerve tissue culture system from dorsal root ganglia of chick embryos was used to test the effects of tri- o -tolyl phosphate (TOTP), its metabolites and di-isopropylphosphorofluoridate (DFP). Cytotoxic responses consisted of reduction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e747f80db3a0f1c253a3b1ab18f6e87
https://doi.org/10.1016/0021-9975(75)90024-9
https://doi.org/10.1016/0021-9975(75)90024-9
Publikováno v:
Toxicology and Applied Pharmacology. 62:137-151
Male B6C3F1 mice metabolized inhaled trichloroethylene (TRI) (600 ppm/6 hr) to a greater extent (262% more) than male Osborne-Mendel rats. Mice metabolized more (332%) inhaled TRI to a hepatic macromolecular binding metabolite in vivo than rats. Oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0d0060512c62f5ade8e4ce54fdf24c
https://doi.org/10.1016/0041-008x(82)90110-7
https://doi.org/10.1016/0041-008x(82)90110-7
Autor:
J.F. Quast, Tony R. Fox, Patrick W. Langvardt, P.G. Watanabe, John C. Ramsey, Richard H. Reitz
Publikováno v:
Toxicology and Applied Pharmacology. 62:190-204
Ethylene dichloride (EDC) induces tumors in rats and mice when administered chronically by gavage. However, chronic inhalation of EDC vapor failed to induce any treatment-related tumors. To help understand the consequences of environmental exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5856fc4a565583f4894488a85d1eab64
https://doi.org/10.1016/0041-008x(82)90117-x
https://doi.org/10.1016/0041-008x(82)90117-x
Publikováno v:
Toxicology and Applied Pharmacology. 34:529-532
Percutaneous absorption of 14c-labeled vinyl chloride (VC) was examined in male rhesus monkeys. Two monkeys were exposed (whole body, excluding the head) to atmospheres containing 7000 and 800 ppm of VC for 2.0 and 2.5 hr, respectively. The amount of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fc8bc8c3de6343e7e9fece6c2b83f2
https://doi.org/10.1016/0041-008x(75)90149-0
https://doi.org/10.1016/0041-008x(75)90149-0
Publikováno v:
Toxicology and Applied Pharmacology. 44:571-579
Covalent binding of radioactivity to hepatic macromolecules in rats exposed to 14C-labeled vinyl chloride (VC) was studied to determine if VC-induced carcinogenesis may be related to electrophilic alkylation of macromolecules in vivo. Male Sprague-Da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db41325b65e2da019bdb4bf6b4963872
https://doi.org/10.1016/0041-008x(78)90265-x
https://doi.org/10.1016/0041-008x(78)90265-x
Publikováno v:
Journal of Labelled Compounds. 11:535-542
A modification of our previously reported2 gas chromatographic method of preparing vinyl-14C2 chloride (14C-VC) has been made. The procedure using 1,2-dichloroethane-14C2 obtained from New England Nuclear Corporation gave good yields of 14C-VC as a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5cb761c0171a15e1fb3993285aaccf1
https://doi.org/10.1002/jlcr.2590110410
https://doi.org/10.1002/jlcr.2590110410
Publikováno v:
Annals of the New York Academy of Sciences. 329:137-152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84172d25582244edc852fc0400688c8
https://doi.org/10.1111/j.1749-6632.1979.tb15341.x
https://doi.org/10.1111/j.1749-6632.1979.tb15341.x