Zobrazeno 1 - 10
of 56
pro vyhledávání: '"P.G. Bundesen"'
Publikováno v:
Immunology and Cell Biology. 71:117-124
The antifibrin DD-3B6/22 monoclonal antibody Fab' fragment, a murine immunoglobulin, IgG3, has been labelled with technetium-99 m (99mTc) via a transchelation reaction, to specific activity in excess of 30 mCi/mg protein. The radiolabelling of Fab' w
Autor:
P.G. Bundesen, G.R. Boniface, L. J. Milner, A. R. J. Weedon, K. Z. Walker, Fook-Thean Lee, George J. Bautovich, D.B. Rylatt
Publikováno v:
Immunology and Cell Biology. 70:173-179
Technetium-99 m (99mTc)-labelled conjugates of an anti-fibrin monoclonal antibody, DD-3B6/22, have been assessed for their detection of vascular thrombi in a rabbit model. DD-3B6/22 binds to a D-dimer epitope present on cross-linked fibrin but absent
Publikováno v:
Thrombosis Research. 64:691-701
Injection of 99mTc-labeled Fab' fragments of the anti-fibrin antibody DD3B6/22, in the baboon, resulted in clear visualisation of both fresh and aged autologous thrombi by gamma scintigraphy. Whole body scintigraphy, pharmacokinetics and urine analys
Publikováno v:
Thrombosis Research. 58:273-281
A new system for the detection of fibrin degradation products in whole blood has been developed. The test provides a clearly visible agglutination of the patient's red blood cells in the presence of elevated levels of the crosslinked fibrin derivativ
Publikováno v:
International Journal for Parasitology. 19:91-98
A total of 37 Giardia stocks isolated from humans and 14 stocks derived from animal sources have been analysed for antigenic differences. Separation of the proteins of the stocks by polyacrylamide gel electrophoresis showed no major differences among
Autor:
D. Wyatt, Paul P. Masci, D.B. Rylatt, A.S. Blake, I H Bunce, A.N. Whitaker, M J Elms, W.A. Fletcher, D.A. Massingham, P.G. Bundesen, L.E. Cottis, A.J. Webber
Publikováno v:
Thrombosis Research. 31:767-778
Monoclonal antibodies (MAb) were raised against human D dimer. The hybridomas were screened with a solid phase enzyme immunoassay against D dimer and fibrinogen degradation products. Among the panel of MAb identified, two distinct patterns emerged; t
Publikováno v:
Thrombosis Research. 52:269-278
The D Dimer (DD) site formed by linkage of D domains from adjacent fibrin (FN) molecules is unique to cross-linked FN and its degradation products and is not found in FN monomer or fibrinogen (FB). Thus monoclonal antibodies (MAb) reactive to DD shou
Autor:
P.G. Bundesen, P.A. Janssens
Publikováno v:
International Journal for Parasitology. 1:15-20
• Seven rabbits were infected with varying numbers of Taenia pisiformis oncospheres. Gluatamate pyruvate transaminase (GPT) and gluatamate dehydrogenase (GDH) activities were assayed on samples of plasma taken from each rabbit at infection and on a
Publikováno v:
Lancet (London, England). 1(8537)
An enzyme immunosassay (EIA) with monoclonal antibodies against human trypsinogen in neonatal blood-spots has been evaluated for screening for neonatal cystic fibrosis (CF). In a retrospective study, 36 of 39 CF samples were distinguished from contro
Autor:
L.E. Cottis, Alan Radford, J.L. Ripper, P. R. Wood, P. Plackett, M. John, P.G. Bundesen, D. B. Rylatt
Publikováno v:
Journal of general microbiology. 134(9)
Summary: A series of monoclonal antibodies (MAbs), specific for Mycobacterium bovis and BCG strains, were tested extensively for cross-reactivity to a wide range of mycobacterial species using ELISA, Western blotting and dot-blot analysis. The MAbs b