Zobrazeno 1 - 10
of 60
pro vyhledávání: '"P.D. Kittlick"'
Publikováno v:
Experimental and Toxicologic Pathology. 46:383-388
Antigen-induced arthritis in guinea pigs was used as a model to investigate the pathogenic mechanisms responsible for cartilage destruction in chronic joint inflammation. The activation of macrophages, their effects on cartilage metabolism, and the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b298d384da7632971da665648568e304
https://doi.org/10.1016/s0940-2993(11)80121-1
https://doi.org/10.1016/s0940-2993(11)80121-1
Autor:
D. Engelmann, P.D. Kittlick
Publikováno v:
Experimental and Toxicologic Pathology. 45:87-92
Macrophages produce and secrete proteoglycans. They are involved in inflammation and may contribute to the glycosaminoglycans (GAG) and proteoglycans (PG) characteristic of the inflamed area. This possible contribution was studied with rat peritoneal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0eab36b904bde70fc622b789915493d
https://doi.org/10.1016/s0940-2993(11)80469-0
https://doi.org/10.1016/s0940-2993(11)80469-0
Publikováno v:
Experimental pathology. 41:147-150
Summary There are only few reports on the correlation between bacterial products and the GAG pattern of cartilage. Mycobacteria bovis (BCG) were applied to chondrocyte monolayer cultures for one week. The following parameters did change: - cell proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff72eecafa04f2745927d8de786ead8b
https://doi.org/10.1016/s0232-1513(11)80103-9
https://doi.org/10.1016/s0232-1513(11)80103-9
Publikováno v:
Experimental pathology. 41:98-109
Summary Chondrocyte cultures may serve as a model in investigating changes of the cartilage metabolism. Adherent chondrocytes in vitro maintain polygonal morphology at high cell density in the primary and secondary culture. Collagen type II is only c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2564ae92f91df0ee26fc920bb94159ca
https://doi.org/10.1016/s0232-1513(11)80006-x
https://doi.org/10.1016/s0232-1513(11)80006-x
Effect of the microbial constituents, LPS and BCG, on the glycosaminoglycans of chondrocyte cultures
Autor:
P.D. Kittlick, D. Engelmann
Publikováno v:
Experimental pathology. 42:145-150
Summary Earlier we reported that articular chondrocytes in monolayer culture produce pericellular proteoglycans both with short and long half lives, T-1 and T-2 (Kittlick et al. 1991b). Now monolayer cultures have been investigated to assess the infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2feba78e5757c9c02e4e954a341cb24c
https://doi.org/10.1016/s0232-1513(11)80014-9
https://doi.org/10.1016/s0232-1513(11)80014-9
Autor:
P.D. Kittlick
Publikováno v:
Experimental pathology. 42(3)
It is demonstrated that conditioned media of articular chondrocytes cultured with Bacilli Calmette-Guerin are capable of activating macrophages. This activation reaches different levels and is expressed both by different cell survival and enhanced sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb6a05c8210220453d2fc33ffaa0c15
https://pubmed.ncbi.nlm.nih.gov/1915760
https://pubmed.ncbi.nlm.nih.gov/1915760
Autor:
M. Danz, P.D. Kittlick
Publikováno v:
Experimentelle Pathologie. 13:139-144
Summary In the adrenals of male Sprague-Dawley rats the concentration of cyclic 3′,5′-adenosine monophosphate (cAMP) was studied 5, 10, 14, 24, 30 and 39 hours after single intoxication by 2-acetylaminofluorene (AAF) or allylic alcohol (ALL). Bes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::748f05929c6bbb67543fa8f72f2d4f0d
https://doi.org/10.1016/s0014-4908(77)80040-9
https://doi.org/10.1016/s0014-4908(77)80040-9
Autor:
D. Engelmann, P.D. Kittlick
Publikováno v:
Experimental Pathology. 34:245-252
Summary The macrophage-like cell line PeMa was cultured both in suspension and in monolayer for biochemical studies. It is concluded that adherent PeMa when compared with suspended cells contain three times more GAG in medium, cell coat, and cells; -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58884ef2df53b87c5a4bdfadaace724
https://doi.org/10.1016/s0232-1513(88)80157-9
https://doi.org/10.1016/s0232-1513(88)80157-9
Publikováno v:
Experimentelle Pathologie. 18:197-203
Summary From 16 synovial membranes of patients with rheumatoid arthritis morphological parameters as well as the GAG distribution pattern have been determined using 2 methods each. The results were checked by discriminant and regression analysis: The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4625623e07af275d29c7d62e52cc4985
https://doi.org/10.1016/s0014-4908(80)80049-4
https://doi.org/10.1016/s0014-4908(80)80049-4
Publikováno v:
Experimentelle Pathologie. 12:236-241
From cells and culture media of embryonic rat fibroblasts (1st subculture) the acid mucopolysaccharides were isolated and fractionated. The per cent calculation of the 6 fractions was based on the content of glucuronic acid. The cultures were maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1135b2e0891fe289cda942b9318ebc53
https://doi.org/10.1016/s0014-4908(76)80020-8
https://doi.org/10.1016/s0014-4908(76)80020-8