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Separate and combined effects of growth hormone and parathyroid hormone on cortical bone osteopenia in ovariectomized aged rats

Autor: Dike N. Kalu, P.B Orhii, M. J. Banu, L. Wang

Publikováno v: Aging Clinical and Experimental Research. 13:282-292

The focus of this study is on whether cortical osteopenia occurs in ovariectomized aged female rats, and if so, whether growth hormone (GH) and parathyroid hormone (PTH) independently or together (GH+PTH) can rebuild the lost cortical bone. Tibio-fib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18fb2b31487678626e31fe61ddf1cb7
https://doi.org/10.1007/bf03353424

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Parathyroid hormone and growth hormone have additive or synergetic effect when used as intervention treatment in ovariectomized rats with established osteopenia

Autor: P.B Orhii, M. J. Banu, L Tornvig, Jesper Skovhus Thomsen, Dike N. Kalu, Li. Mosekilde

Publikováno v: Mosekilde, L, Erikstrup, L T, Thomsen, J S, Orhii, P B, Banu, M J & Kalu, D N 2000, ' Parathyroid hormone and growth hormone have additive or synergetic effect when used as intervention treatment in ovariectomized rats with established osteopenia ', Bone, vol. 26, no. 6, pp. 643-51 . https://doi.org/10.1016/S8756-3282(00)00276-3

The severely osteoporotic human skeleton is characterized by thin cortices and a very fragile cancellous framework. To increase the biomechanical competence of such a skeleton, powerful anabolic agents are needed. The aim of the present study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6159f8e71df34b227a611c6244afb4dc
https://doi.org/10.1016/s8756-3282(00)00276-3

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Analysis of the effects of growth hormone, voluntary exercise, and food restriction on diaphyseal bone in female F344 rats

Autor: Lis Mosekilde, P.B Orhii, M. J. Banu, W Mejia, R.J.M McCarter, Dike N. Kalu, Jesper Skovhus Thomsen

Publikováno v: Banu, M J, Orhii, P B, Mejia, W, McCarter, R J, Mosekilde, L, Thomsen, J S & Kalu, D N 1999, ' Analysis of the effects of growth hormone, voluntary exercise, and food restriction on diaphyseal bone in female F344 rats ', Bone, vol. 25, no. 4, pp. 469-80 . https://doi.org/10.1016/S8756-3282(99)00195-7

The aim of this study is to examine the effects of growth hormone, exercise, and weight loss due to food restriction on tibial diaphyseal bone and on tibial muscle mass. Thirteen-month-old female F344 rats were divided into six groups: group 1, basel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c218f34e6ebedc1b419a182d9aacb66
https://pubmed.ncbi.nlm.nih.gov/10511115

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Additive effect of voluntary exercise and growth hormone treatment on bone strength assessed at four different skeletal sites in an aged rat model

Autor: Dike N. Kalu, R.J.M McCarter, P.B Orhii, Lis Mosekilde, W Mejia, Jesper Skovhus Thomsen

Publikováno v: Mosekilde, L, Thomsen, J S, Orhii, P B, McCarter, R J, Mejia, W & Kalu, D N 1999, ' Additive effect of voluntary exercise and growth hormone treatment on bone strength assessed at four different skeletal sites in an aged rat model ', Bone, vol. 24, no. 2, pp. 71-80 . https://doi.org/10.1016/S8756-3282(98)00169-0

The aim of the study was to assess the effect of growth hormone (GH), voluntary exercise (Ex), and the combination of GH and Ex on bone strength, mass, and dimensions in aged, intact female rats. In addition, the effect of food restriction (FR) was s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763b3767302481a67150d1737f975874
https://pubmed.ncbi.nlm.nih.gov/9951773

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Growth hormone increases vertebral and femoral bone strength in osteopenic, ovariectomized, aged rats in a dose-dependent and site-specific manner

Autor: Jesper Skovhus Thomsen, Li. Mosekilde, P.B Orhii, Dike N. Kalu

Publikováno v: Mosekilde, L, Thomsen, J S, Orhii, P B & Kalu, D N 1998, ' Growth hormone increases vertebral and femoral bone strength in osteopenic, ovariectomized, aged rats in a dose-dependent and site-specific manner ', Bone, vol. 23, no. 4, pp. 343-52 . https://doi.org/10.1016/S8756-3282(98)00107-0

The aim of the study was to assess the effect of growth hormone (GH) as restorative therapy in an aged, ovariectomized rat model with established osteopenia. The study was planned as a dose-response study, and four different skeletal sites were inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bba81bf85fcda74dd645e5de7e9a92c
https://pure.au.dk/portal/da/publications/growth-hormone-increases-vertebral-and-femoral-bone-strength-in-osteopenic-ovariectomized-aged-rats-in-a-dosedependent-and-sitespecific-manner(9837a0a0-8aa0-451a-9e62-e3a63562f4c5).html

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