Zobrazeno 1 - 10 of 371 pro vyhledávání: '"P.A.M. van Leeuwen"'
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The interval between primary melanoma excision and sentinel node biopsy is not associated with survival in sentinel node positive patients – An EORTC Melanoma Group study
Autor: A.C.J. van Akkooi, Dirk J. Grünhagen, Harald J. Hoekstra, Barry W.E.M. Powell, Christiane Voit, J.A. van der Hage, C. M. C. Oude Ophuis, Alexander M.M. Eggermont, Alessandro Testori, Caroline Robert, P.A.M. van Leeuwen, Cees Verhoef, Piotr Rutkowski
Publikováno v: European Journal of Surgical Oncology, 42(12), 1906-1913. ELSEVIER SCI LTD
European Journal of Surgical Oncology, 42(12), 1906-1913. W.B. Saunders
Background: Worldwide, sentinel node biopsy (SNB) is the recommended staging procedure for stage I/II melanoma. Most melanoma guidelines recommend re-excision plus SNB as soon as possible after primary excision. To date, there is no evidence to suppo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebf165b97461dae748d945ef0e658f5
https://doi.org/10.1016/j.ejso.2016.05.012
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3
Nutritional support in patients with GVHD of the digestive tract: state of the art
Autor: Nicolette J. Wierdsma, Jeroen Janssen, Otto Visser, Jacqueline A.E. Langius, B.S. van der Meij, P. de Graaf, P.A.M. van Leeuwen
Publikováno v: van der Meij, B S, de Graaf, P, Wierdsma, N J, Langius, J A E, Janssen, J J W M, van Leeuwen, P A M & Visser, O J 2013, ' Nutritional support in patients with GVHD of the digestive tract: state of the art ', Bone Marrow Transplantation, vol. 48, no. 4, pp. 474-482 . https://doi.org/10.1038/bmt.2012.124
Bone Marrow Transplantation, 48(4), 474-482. Nature Publishing Group
An important complication of allo-SCT is GVHD, which commonly affects the skin, liver and digestive tract. Clinical symptoms of GVHD of the digestive tract (GVHD-DT) include excessive diarrhoea, abdominal pain and cramps, nausea and vomiting, gastroi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1beaaba167b10a225ff7723efc5ed23
https://doi.org/10.1038/bmt.2012.124
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4
The Role of a Disturbed Arginine/NO Metabolism in the Onset of Cancer Cachexia: A Working Hypothesis
Autor: P.A.M. van Leeuwen, A. P. J. Houdijk, Nikki Buijs, J. Luttikhold
Publikováno v: Current Medicinal Chemistry, 19(31), 5278-5286. Bentham Science Publishers B.V.
Buijs, N, Luttikhold, J, Houdijk, A P & van Leeuwen, P A M 2012, ' The Role of a Disturbed Arginine/NO Metabolism in the Onset of Cancer Cachexia: A Working Hypothesis ', Current Medicinal Chemistry, vol. 19, no. 31, pp. 5278-5286 . https://doi.org/10.2174/092986712803833290
Cancer cachexia is a complex catabolic state in patients with a malignancy, associated with increased morbidity and mortality. This syndrome is characterized by a redistribution of the body's protein content and a subsequent muscle wasting. The aetio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7429e734d4e80e3caad52a44fa572314
https://doi.org/10.2174/092986712803833290
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5
Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT
Autor: Jacqueline A.E. Langius, P.A.M. van Leeuwen, B.S. van der Meij, Egbert F. Smit, S.M. Slootmaker, Marieke D. Spreeuwenberg, Marinus A. Paul
Publikováno v: European Journal of Clinical Nutrition
European Journal of Clinical Nutrition, 66(3), 399-404. Nature Publishing Group
van der Meij, B S, Langius, J A E, Spreeuwenberg, M D, Slootmaker, S M, Paul, M A, Smit, E F & van Leeuwen, P A M 2012, ' Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT ', European Journal of Clinical Nutrition, vol. 66, no. 3, pp. 399-404 . https://doi.org/10.1038/ejcn.2011.214
Background/Objectives: Our objective was to investigate effects of an oral nutritional supplement containing n-3 polyunsaturated fatty acids (FAs) on quality of life, performance status, handgrip strength and physical activity in patients with non-sm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98929830e7c3cac2a8e389a69b27f24
https://cris.maastrichtuniversity.nl/en/publications/371a5350-27c3-4ae3-a547-7dffed6696c0
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6
4-1BB-mediated expansion affords superior detection of in vivo primed effector memory CD8+ T cells from melanoma sentinel lymph nodes
Autor: P.A.M. van Leeuwen, Berbel J.R. Sluijter, Saskia J. A. M. Santegoets, Rik J. Scheper, Sinéad M. Lougheed, A.J.M. van den Eertwegh, M.P. van den Tol, Megan M. Suhoski, M.F.C.M. van den Hout, Anita G.M. Stam, T.D. de Gruijl, Sybren L. Meijer, Carl H. June
Publikováno v: Clinical Immunology, 137(2), 221-233. Academic Press Inc.
Sluijter, B J R, van den Hout, M F C M, Stam, A G M, Lougheed, S M, Suhoski, M M, van den Eertwegh, A J M, van den Tol, M P, van Leeuwen, P A M, Meijer, S, Scheper, R J, June, C H, de Gruijl, T D & Santegoets, S J A M 2010, ' 4-1BB-mediated expansion affords superior detection of in vivo primed effector memory CD8(+) T cells from melanoma sentinel lymph nodes ', Clinical Immunology, vol. 137, no. 2, pp. 221-233 . https://doi.org/10.1016/j.clim.2010.07.009
We have been studying the re-activation of tumor-associated antigen (TAA)-specific CD8 + T cells in sentinel lymph nodes (SLN) of melanoma patients upon intradermal administration of the CpG-B oligodeoxynucleotide PF-3512676. To facilitate functional
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3283daaeeadfca9b8067d241779580f5
https://doi.org/10.1016/j.clim.2010.07.009
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7
The citrulline generation test: proposal for a new enterocyte function test
Autor: P.A.M. van Leeuwen, Cjj Mulder, A.A. van Bodegraven, Job H.C. Peters, Tom Teerlink, Nicolette J. Wierdsma
Publikováno v: Alimentary Pharmacology & Therapeutics. 27:1300-1310
SUMMARY Background The amino acid citrulline is mainly produced by enterocytes from conversion of glutamine. As fasting plasma citrulline proved disappointing as a biomarker for enterocyte dysfunction in clinical practice, we propose a citrulline gen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c338ec0114cab4588d6b42d393cc7d95
https://doi.org/10.1111/j.1365-2036.2008.03678.x
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Immunological consequences of laparoscopic versus open transhiatal resection for malignancies of the distal esophagus and gastroesophageal junction
Autor: P.A.M. van Leeuwen, Colin Sietses, Gerdien C. Ligthart-Melis, D.G. Bos, C.M.W. Teunissen, J.J.G. Scheepers, Petra G. Boelens, Miguel A. Cuesta
Publikováno v: Digestive Surgery, 25(2), 140-147. S. Karger AG
Scheepers, J J, Sietses, C, Bos, D G, Boelens, P G, Teunissen, C M, Melis, G C, Cuesta, M A & van Leeuwen, P A M 2008, ' Immunological consequences of laparoscopic versus open transhiatal resection for malignancies of the distal esophagus and gastroesophageal junction ', Digestive Surgery, vol. 25, no. 2, pp. 140-147 . https://doi.org/10.1159/000128171
Background/Aim: Surgery remains the only curative therapy for esophageal cancer. The objective of the current study was to evaluate the impact of laparoscopic transhiatal esophagectomy versus open transhiatal esophagectomy on both inflammatory and im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07573495e6f2dbb84f97f4a6f0eaf6d
https://doi.org/10.1159/000128171
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9
Fetal magnetocardiography in an unshielded environment
Autor: Dietrich Grönemeyer, Silke Lange, D. Geue, Ronny Stolz, H. G. Meyer, P.A.M. van Leeuwen, Michael Schulz, W. Hatzmann, N. Bondarenko, V. Zakosarenko, Sven Schiermeier
Publikováno v: International Congress Series. 1300:757-760
We investigated the viability of a 2-channel low temperature biomagnetometer system implementing 2nd order gradiometers in an unshielded environment. We examined 2 fetuses (30th, 38th week of gestation) in and outside a shielded room as well as 3 (we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47d97978fda7c1924fe130bf7973e78b
https://doi.org/10.1016/j.ics.2007.02.005
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10
Detection and analysis of fetal arrhythmia in a single twin fetus using magnetocardiography
Autor: D. Geue, Birgit Hailer, Sven Schiermeier, P.A.M. van Leeuwen, Silke Lange, W. Hatzmann, Dietrich Grönemeyer
Publikováno v: International Congress Series. 1300:765-768
An important clinical application of fetal magnetocardiography (FMCG) is the identification and classification of fetal arrhythmias. However, separation of fetal and maternal signals can be challenging due to cardiac conduction disturbances and chang
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f3238d904ad7a30a638e88855554e38
https://doi.org/10.1016/j.ics.2007.02.002
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