Zobrazeno 1 - 10
of 29
pro vyhledávání: '"P.A. Pipkin"'
Autor:
Glyn Stacey, P.D. Minor, Roland A. Fleck, P.A. Pipkin, V. Dussupt, David J. Hockley, M.A. Afzal
Publikováno v:
Journal of Virological Methods. 126:149-156
Vero cells have been used as a convenient laboratory substrate for the isolation of mumps virus but may not be very sensitive and may select for particular adapted variants from clinical specimens. Continuous cell lines were evaluated for their abili
Publikováno v:
Virology. 330(1):1-7
The presence of SV40 viral particles in the environment of cynomolgus monkeys naturally infected with this virus has been analyzed by testing waste of the cage samples.SV40 was detected in 2/4 cages tested where mixed infection of SV40 and adenovirus
Publikováno v:
Vaccine. 19:3467-3471
It has been reported that the rate of growth of SV40 in certain cell culture systems is affected by the number of copies of the enhancer element, and that this might in turn affect the ability of manufacturers of polio vaccines to detect SV40 contami
Publikováno v:
Vaccine. 19:442-446
Several preparations of MMR vaccines and their progenitor monovalent vaccine bulks produced by two different manufacturers were examined serologically for the presence of chicken myelin basic protein (MBP) residues. The products were challenged again
Autor:
P.D. Minor, P.A. Pipkin
Publikováno v:
Biologicals. 26:17-23
The Children's Vaccine Initiative established a Product Development Group in 1991 to help in the development of oral poliovaccines of improved thermostability. Under the auspices of this group, the effect of different stabilizers on the loss of infec
Autor:
Richard M. Kaufman, N.A. Clarkson, P.A. Pipkin, Jeffrey W. Almond, David J.A. Evans, Trevor Ward, D M Lublin, P D Minor
Publikováno v:
Journal of Virology. 69:5497-5501
CD55, or decay-accelerating factor (DAF), is a cell surface glycoprotein which regulates complement activity by accelerating the decay of C3/C5 convertases. Recently, we and others have established that this molecule acts as a cellular receptor for e
Publikováno v:
Journal of Virological Methods. 41:333-340
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 27(1)
Neurovirulence tests in Macaca fascicularis using commercial preparations of different vaccine bulks and a wild-type strain revealed that the test was unable to distinguish mixed from pure populations or a suitable vaccine from a related strain which
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 27(1)
Oral poliovaccines derived from the strains developed by Sabin have been the basis of vaccination against poliomyelitis in the U.K. since 1962. Contamination of earlier materials with the monkey virus SV40, particularly inactivated Salk type poliovac
Publikováno v:
Journal of virological methods. 79(2)
One hundred randomly chosen sera from blood donors from North London were assayed for antibodies to mumps virus by plaque reduction and microtitre neutralisation assay, haemagglutination inhibition and in-house ELISA. The assay reproducibility was de