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Brain autoradiographic study in the golden hamster after intracarotid injection of [14C]melatonin

Autor: P.A. Vitte, Bruno Claustrat, Paul Pévet, Catherine Harthé

Publikováno v: Neuroscience Letters. 110:1-5

The distribution of [14C]melatonin ([14C]MT) after systemic injection was studied in the plasma and brain of golden hamsters. Thin-layer chromatographic analysis indicated that the radioactivity of the biological samples taken at two different times

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a8d89cfcc7707494bd450f0f821fd6
https://doi.org/10.1016/0304-3940(90)90777-7

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PET and plasma pharmacokinetic studies after bolus intravenous administration of [11C]melatonin in humans

Autor: R.S.J Frackowiak, G Chazot, J Arendt, P.A Vitte, D. Le Bars, P Thivolle, Bruno Claustrat, C Bojkowski

Publikováno v: Europe PubMed Central

A human PET study was performed with carbon-11 labelled melatonin in a healthy volunteer. Plasma pharmacokinetics of melatonin and 6-sulfatoxymelatonin were simultaneously determined using radioimmunoassay. Analysis of tracer kinetics showed maximum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3f6a6867114d0d98970e801512a5a4
https://pubmed.ncbi.nlm.nih.gov/2071448

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Plasma, Cerebrospinal Fluid, and Brain Distribution of14C-Melatonin in Rat: A Biochemical and Autoradiographic Study

Autor: P.A. Vitte, C. Harthe, Bruno Claustrat, P. Bobillier, P. Lestage

Publikováno v: Journal of Pineal Research. 5:437-453

The distribution of 14C-Melatonin (14C-MT) after systemic injection was studied in the plasma, cerebrospinal fluid (CSF), and brain of rats. Chromatographic analysis (thin-layer chromatography and high-performance liquid chromatography) indicated tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f44f83ebc97ed3e9aeeb3bc022d8e5
https://doi.org/10.1111/j.1600-079x.1988.tb00787.x

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An In Vivo Kinetic Model with L-[35S]Methionine for the Determination of Local Cerebral Rates for Methionine Incorporation into Protein in the Rat

Autor: Dominique Lecestre, M. Gonon, P. Bobillier, P.A. Vitte, G. Debilly, P. Lestage, C. Rossatto, P. Lepetit

Publikováno v: Journal of Neurochemistry. 48:352-363

A method has been developed for the simultaneous in vivo measurement of local rates for methionine incorporation into cerebral protein in the rat. It is based on the use of l-[35S]methionine as a tracer for reflecting the bidirectional exchange of me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ca85b387ebdcc11d4bd057b4ce9353
https://doi.org/10.1111/j.1471-4159.1987.tb04101.x

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A chronic arterial and venous cannulation method for freely moving rats

Autor: P.A. Vitte, J.P. Rolinat, E. Broussolle, P. Bobillier, R. Minot, P. Lestage

Publikováno v: Journal of neuroscience methods. 13(3-4)

A chronic arterial and venous cannulation method appropriate for pharmacokinetics studies in freely moving rats is described. Two catheters were implanted: one in the abdominal aorta, the other in the inferior vena cava. Passing subcutaneously, the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0bd9c185f516fdcb1830e9c406f0027
https://pubmed.ncbi.nlm.nih.gov/4040194

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Apomorphine-induced inhibition of substantia nigra dopamine neurons: Effects of unilateral injection through the internal carotid artery

Autor: Hideo Akaoka, Guy Chouvet, P. Lestage, P.A. Vitte, P. Bobillier, Claude Saunier

Publikováno v: Neuroscience Letters
Neuroscience Letters, Elsevier, 1989, 98 (2), pp.205-210. ⟨10.1016/0304-3940(89)90511-9⟩

International audience; Possible indirect components in the inhibition of firing of A9 dopamine neurons induced by systemic apomorphine were studied using unilateral drug administration through the internal carotid artery, known to irrigate only the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9db8c2d2a27f3d8428ddaabe155b27
https://hal.archives-ouvertes.fr/hal-03066893

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Differential effects of chronic dehydration on protein synthesis in neurons of the rat hypothalamus

Autor: P.A. Vitte, P. Bobillier, Patrick Lepetit, G. Gauquelin, Michel Jouvet, P. Lestage, G. Debilly, C. Gharib

Publikováno v: Neuroscience letters. 62(1)

The rate of methionine incorporation was measured in individual hypothalamic nuclei by a quantitative autoradiographic technique: the l -[ 35 S]methionine method. Physiological stimulation of the hypothalamo-neurohypophysial system by two days of wat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823f14f40d25efa776df4802e3fda105
https://pubmed.ncbi.nlm.nih.gov/4069449

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