Zobrazeno 1 - 10
of 38
pro vyhledávání: '"P.-M. G. Bouloux"'
Autor:
Stephen L. Atkin, J Chapman, Harpal S. Randeva, John S. Bevan, P.-M. G. Bouloux, A Viswanath, John A.H. Wass, John Newell-Price, Paul M. Stewart, Julian R. E. Davis, Trevor A. Howlett
Publikováno v:
Clinical Endocrinology
Summary Objective The introduction of ready-to-use lanreotide Autogel® has presented the possibility of patients receiving their acromegaly treatment at home. The objective of this study was to assess the ability of patients (or their partners) to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306db01f2f6940e11073ac3a98905c69
http://europepmc.org/articles/PMC2268964
http://europepmc.org/articles/PMC2268964
Publikováno v:
Journal of Endocrinology. 176:293-304
GnRH and sex steroids play an important role in immune system modulation and development. GnRH and the GnRH receptor are produced locally by immune cells, suggesting an autocrine role for GnRH. Experimental studies show a stimulatory action of exogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062d398f12050570e8daae58efb38502
https://doi.org/10.1677/joe.0.1760293
https://doi.org/10.1677/joe.0.1760293
Autor:
J. A. H. Wass, Stephen L. Atkin, G. A. Roberts, M. McConnell, Maurice F. Scanlon, F. Hanna, H. E. Turner, P. E. Harris, P.-M. G. Bouloux, A. B. Atkinson, John S. Bevan, Paul M. Stewart, R. A. James, E. Teasdale, Joanna M. Wardlaw
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:4554-4563
Conventional surgery and radiotherapy for acromegaly have limitations. There are few data on the use of the somatostatin analog octreotide (Oct) as primary medical therapy. An open prospective study of 27 patients with newly diagnosed acromegaly was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b87ba6825bab952476bcf5373ca233
https://doi.org/10.1210/jc.2001-012012
https://doi.org/10.1210/jc.2001-012012
Publikováno v:
Journal of Endocrinology. 162:1-9
Gene transfer into muscle tissue is currently being developed as a method for the production, secretion and delivery of therapeutic proteins. This methodology has been used to produce a variety of physiologically active proteins and may ultimately be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af27c2ff6c30a8b1b5c0f41e7688b0ec
https://doi.org/10.1677/joe.0.1620001
https://doi.org/10.1677/joe.0.1620001
Autor:
M White, P.-M. G. Bouloux, Jeremy Kirk, G. M. Besser, C S Smith, Richard Quinton, David B. Grant, Owain R. Edwards, Stephen M Shalet
Publikováno v:
Clinical Genetics. 46:260-262
Unilateral renal agenesis is an uncommon association with Kallmann's syndrome (KS) (hypogonadotrophic hypogonadism and olfactory defect). We have investigated affected individuals from six pedigrees: five with X-linked KS, and one with X-linked KS an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfd7a3bbdcf5191221c6a7b28953edd
https://doi.org/10.1111/j.1399-0004.1994.tb04238.x
https://doi.org/10.1111/j.1399-0004.1994.tb04238.x
Publikováno v:
Brain. 120:1199-1216
Possible mechanisms underlying the pathological mirror movements that are seen in the majority of patients with X-linked Kallmann's syndrome have been investigated using neurophysiological techniques. An EMG was recorded from the first dorsal interos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f85b2a31dd8b409d1c8bc3eac1ac8fe
https://doi.org/10.1093/brain/120.7.1199
https://doi.org/10.1093/brain/120.7.1199
Publikováno v:
British Journal of Pharmacology. 120:781-784
1. Opioid drugs act on specific receptors which are principally classified into mu, delta and kappa subtypes. Spiradoline (U-62066E) is a kappa-selective agent which has been shown to possess potent anti-nociceptive effects but does not show cross to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9631b261e9728120fedecd318561b05
https://doi.org/10.1038/sj.bjp.0700971
https://doi.org/10.1038/sj.bjp.0700971
Autor:
M. Fakeeh, P.-M. G. Bouloux
Publikováno v:
Clinical Endocrinology. 43:657-664
Summary OBJECTIVE Fasting is known to clearly increase both spontaneous and GHRH-stimulated GH secretion in normal subjects and this effect is likely to be due to hypothalamic mechanism(s). Our aim was to clarify the effect of a 3 or 4-day fast, on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe5fcbd43147016ef7ea601d25e1048
https://doi.org/10.1111/j.1365-2265.1995.tb00531.x
https://doi.org/10.1111/j.1365-2265.1995.tb00531.x
Autor:
A P, Walker, R C, Fowkes, F, Saleh, S-H, Kim, P, Wilkinson, V, Cabrera-Sharp, P J, Talmud, S E, Humphries, L H J, Looijenga, P M G, Bouloux
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation. 6(6)
There have been few testicular histology reports of adult patients with congenital adrenal hypoplasia/hypogonadal hypogonadism (AHC/HH), but Leydig cell hyperplasia has been observed, an indicator of the possibility of malignant transformation. We ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fde71632f4540cbfd9ffba58636a673f
https://pubmed.ncbi.nlm.nih.gov/23018754
https://pubmed.ncbi.nlm.nih.gov/23018754
Autor:
T S, Han, P M G, Bouloux
Publikováno v:
Clinical endocrinology. 72(6)
Hypogonadotropic hypogonadism (HH), consequent to congenital or acquired disorders of the hypothalamic-pituitary axis, presents as absent/delayed/arrested sexual maturation and infertility. Optimal management includes: (a) confirmation of the diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ee81d310c56e00340b99ffdeb3bada3
https://pubmed.ncbi.nlm.nih.gov/19912242
https://pubmed.ncbi.nlm.nih.gov/19912242