Zobrazeno 1 - 10
of 131
pro vyhledávání: '"P. Zanvit"'
Autor:
Jiajia Han, Na Liu, Wenwen Jin, Peter Zanvit, Dunfang Zhang, Junji Xu, Andrew Bynum, Rida Kazmi, Jianmin Zhang, Wei He, WanJun Chen
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract γδ intestinal intraepithelial lymphocytes (IELs) constitute the majority of IELs with unique CD8αα+ homodimers that are distinct from γδT cells in other tissues. However, it remains largely unclear how those cells develop. Here we show
Externí odkaz:
https://doaj.org/article/7f896e72d6804bab9a3b9fb5d014b80f
Autor:
Mark Cobbold, Gordon Moody, Kelly McGlinchey, Emily Bosco, Peter Zanvit, Christine Fazenbaker, Weichuan Luo, Jessica Pezold, Clare Hoover
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e5e673da0a984d5aafd7bab7e39bcc6a
Autor:
Peter Zanvit, Dewald van Dyk, Christine Fazenbaker, Kelly McGlinchey, Weichuan Luo, Jessica M. Pezold, John Meekin, Chien-ying Chang, Rosa A. Carrasco, Shannon Breen, Crystal Sao-Fong Cheung, Ariel Endlich-Frazier, Benjamin Clark, Nina J. Chu, Alessio Vantellini, Philip L. Martin, Clare E. Hoover, Kenesha Riley, Steve M. Sweet, David Chain, Yeoun Jin Kim, Eric Tu, Nathalie Harder, Sandrina Phipps, Melissa Damschroder, Ryan N. Gilbreth, Mark Cobbold, Gordon Moody, Emily E. Bosco
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
Prostate cancer is generally considered an immunologically “cold” tumor type that is insensitive to immunotherapy. Targeting surface antigens on tumors through cellular therapy can induce a potent antitumor immune response to “heat up” the tu
Externí odkaz:
https://doaj.org/article/e772d4b790a848fcb94aa4259efad645
Autor:
Sang-A Park, Yun-Ji Lim, Wai Lim Ku, Dunfang Zhang, Kairong Cui, Liu-Ya Tang, Cheryl Chia, Peter Zanvit, Zuojia Chen, Wenwen Jin, Dandan Wang, Junji Xu, Ousheng Liu, Fu Wang, Alexander Cain, Nancy Guo, Hiroko Nakatsukasa, Chuan Wu, Ying E. Zhang, Keji Zhao, WanJun Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
IL-9-producing CD4 T (Th9) cells have been implicated in allergy and tumor immunity, but how their differentiation is regulated by TGFβ is still unclear. Here the authors show that two transcription factors, DBP and E2F8, institute opposing effects
Externí odkaz:
https://doaj.org/article/bc8c2332443143d3a8f42e69ddee3045
Akademický článek
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Autor:
Li Wang, Jun Tang, Xia Yang, Peter Zanvit, Kairong Cui, Wai Lim Ku, Wenwen Jin, Dunfang Zhang, Nathan Goldberg, Alexander Cain, Bing Ni, Keji Zhao, Yuzhang Wu, WanJun Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
TGF-β is thought to be important for group 2 innate lymphoid cell (ILC2) function. Here the authors show that TGF-β drives expression of ST2 specifically in ILC2 progenitors and thereby is also important for the development of ILC2s in the bone mar
Externí odkaz:
https://doaj.org/article/a688433a35754ccc8c3fb4caa9137c56
Autor:
Xue Jiao, Xiruo Zhang, Nianyu Li, Dunfang Zhang, Shidou Zhao, Yujie Dang, Peter Zanvit, Wenwen Jin, Zi‐Jiang Chen, Wanjun Chen, Yingying Qin
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Abstract Immune dysregulation has long been proposed as a component of premature ovarian insufficiency (POI), but the underlying mediators and mechanisms remain largely unknown. Here we showed that patients with POI had augmented T helper 1 (TH1) res
Externí odkaz:
https://doaj.org/article/0ffe8d5c7b64440ca94a715dac1749e3
Autor:
Ousheng Liu, Junji Xu, Fu Wang, Wenwen Jin, Peter Zanvit, Dandan Wang, Nathan Goldberg, Alexander Cain, Nancy Guo, Yichen Han, Andrew Bynum, Guowu Ma, Songlin Wang, Zhangui Tang, Wanjun Chen
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102446- (2021)
Summary: Adipose-derived mesenchymal stromal cells (ADSCs) play important roles in the alleviation of inflammation and autoimmune diseases. Interleukin-33 (IL-33), a member of the IL-1 family, has been shown to regulate innate and adaptive immunity.
Externí odkaz:
https://doaj.org/article/ec2ed10c037b45c98daea0c82eae3e6e
Autor:
Shimpei Kasagi, Dandan Wang, Pin Zhang, Peter Zanvit, Hua Chen, Dunfang Zhang, Jia Li, Li Che, Takashi Maruyama, Hiroko Nakatsukasa, Ruiqing Wu, Wenwen Jin, Lingyun Sun, WanJun Chen
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 50-59 (2019)
Background: Clinical trials on multiple sclerosis with repeated injections of monoclonal antibodies depleting CD4+ T cells have not resulted in much success as a disease therapy. Here, we developed an immunotherapy for EAE in mice by combining a tran
Externí odkaz:
https://doaj.org/article/d4d0b41ec287418da99f8fefae91362d
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
TCRαβ+CD8αα+ intraepithelial lymphocytes (IELs) are abundant in gastrointestinal (GI) tract and play an important role in regulation of mucosal immunity and tolerance in the gut. However, it is unknown whether TCRαβ+CD8αα+ IELs exist in the o
Externí odkaz:
https://doaj.org/article/90f49bc040eb4c06a8417673282d3e66