Zobrazeno 1 - 10
of 29
pro vyhledávání: '"P. Y. Holoye"'
Publikováno v:
Cancer Chemotherapy and Pharmacology. 29:145-149
Didemnin B (NSC 325,319), a cyclic depsipeptide isolated from a Caribbean tunicate, exhibits potent preclinical antitumor activity. In previous phase I studies, 3.47 mg/m2 was the maximally tolerated dose, with nausea and vomiting being the dose-limi
Publikováno v:
Cancer. 69(1)
The potential role of paraneoplastic Cushing's syndrome (CS) was assessed on the clinical course of patients with small cell lung cancer. A retrospective comparison was done of complications and survival rates according to the presence or absence of
Autor:
P. Y. Holoye
Publikováno v:
JAMA: The Journal of the American Medical Association. 237:1221-1224
Autor:
P Y, Holoye
Publikováno v:
Comprehensive therapy. 4(2)
Publikováno v:
JAMA. 235(11)
Bleomycin sulfate pulmonary toxicity was encountered in nine of 101 patients receiving high-dose therapy for widespread testicular cancer. The pulmonary presentation was separable into two categories: (1) an early or minimal from with dyspnea on exer
Publikováno v:
Journal of clinical pharmacology. 18(7)
A series of studies were carried out to investigate the pharmacokinetics of the antineoplastic antibiotic bleomycin in patients with neoplastic disorders. Drug was administered by long (four to five days) and short (10 minutes) zero-order infusions,
Publikováno v:
Cancer treatment reports. 61(1)
Publikováno v:
Cancer. 36(2)
Eighty-three patients with Stage II or Stage III germinal neoplasia of the testis and 7 patients with extragonadal primary tumors were treated with bleomycin plus vinblastine, or a five-drug program, bleomycin plus cyclophosphamide, vincristine, meth
Publikováno v:
Cancer. 40(6)
The clinical pharmacology of bleomycin administered by continuous intravenous infusion over a 4 to 5 day period was examined by nine patients. Patients receiving 30 units per day attained an average steady state plasma level of 145.8 (+/- 43.1) ng/ml
Publikováno v:
Seminars in oncology. 9(4 Suppl 1)