Zobrazeno 1 - 10
of 139
pro vyhledávání: '"P. Worth Longest"'
Autor:
Ross L. Walenga, Clare Butler, Brent A. Craven, P. Worth Longest, Raja Mohamed, Bryan Newman, Bo Olsson, Günther Hochhaus, Bing V. Li, Markham C. Luke, Liang Zhao, Andrzej Przekwas, Robert Lionberger
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 5, Pp 560-574 (2023)
Abstract In silico mechanistic modeling approaches have been designed by various stakeholders with the goal of supporting development and approval of generic orally inhaled drug products in the United States. This review summarizes the presentations
Externí odkaz:
https://doaj.org/article/5c0bae85a62f4563a75d8c48d83d86ce
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 956 (2022)
Nasal sprays, which produce relatively large pharmaceutical droplets and have high momentum, are primarily used to deliver locally acting drugs to the nasal mucosa. Depending on spray pump administration conditions and insertion angles, nasal sprays
Externí odkaz:
https://doaj.org/article/24607d4a54ea46c098b3518259cf70d5
Autor:
Ross L. Walenga, Clare Butler, Brent A. Craven, P. Worth Longest, Raja Mohamed, Bryan Newman, Bo Olsson, Günther Hochhaus, Bing V. Li, Markham C. Luke, Liang Zhao, Andrzej Przekwas, Robert Lionberger
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 12:560-574
In silico mechanistic modeling approaches have been designed by various stakeholders with the goal of supporting development and approval of generic orally inhaled drug products in the United States. This review summarizes the presentations and panel
Autor:
Dale Farkas, Laleh Golshahi, Ross Walenga, Michael Hindle, Andrew Babiskin, Sana Hosseini, Arun V. Kolanjiyil, Ali Alfaifi, P. Worth Longest
Publikováno v:
Aerosol Science and Technology. 56:305-322
Autor:
Mohammad A.M. Momin, Serena Bonasera, Michael Hindle, P. Worth Longest, Dale Farkas, Connor Howe
Publikováno v:
Pharm Res
PURPOSE: In order to improve the delivery of dry powder aerosol formulations to the lungs of infants, this study implemented an infant air-jet platform and explored the effects of different air sources, flow rates, and pulmonary mechanics on aerosoli
Publikováno v:
Pharmaceutical research. 39(12)
The objective of this study was to incorporate a passive cyclic loading strategy into the infant air-jet dry powder inhaler (DPI) in a manner that provides high efficiency aerosol lung delivery and is insensitive to powder mass loadings and the prese
Publikováno v:
Pharmaceutics, Vol 6, Iss 1, Pp 26-35 (2014)
Electrostatic charging occurs in most aerosol generation processes and can significantly influence subsequent particle deposition rates and patterns in the respiratory tract through the image and space forces. The behavior of inhaled aerosols with ch
Externí odkaz:
https://doaj.org/article/0e751bf83a644a6f874df977f1eee5fd
Excipient Enhanced Growth Aerosol Surfactant Replacement Therapy in an In Vivo Rat Lung Injury Model
Autor:
P. Worth Longest, Michael Hindle, Sahil R Chindal, Michael S. Valentine, Franck J. Kamga Gninzeko, Sneha Dhapare, Amr Hassan, Susan Boc, Dale Farkas, Rebecca L. Heise, Cindy K. Tho, Mohammad A.M. Momin
Publikováno v:
J Aerosol Med Pulm Drug Deliv
Background: In neonatal respiratory distress syndrome, breathing support and surfactant therapy are commonly used to enable the alveoli to expand. Surfactants are typically delivered through liquid instillation. However, liquid instillation does not
Autor:
Mariette Kemner-van de Corput, Harm A.W.M. Tiddens, Morgan L. Thomas, P. Worth Longest, Karl Bass
Publikováno v:
Aerosol Science and Technology, 55(10), 1143-1164. Taylor & Francis Ltd
The objective of this study was to develop mathematically described characteristic tracheobronchial bifurcations that are representative of aerosol transport and deposition in the intermediate airways of children with cystic fibrosis (CF), where bron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ab9037099d14506b32b4103a2c73a5
https://pure.eur.nl/en/publications/12e10fc1-3965-4ce4-a469-fca5d5db31d5
https://pure.eur.nl/en/publications/12e10fc1-3965-4ce4-a469-fca5d5db31d5
Publikováno v:
J Aerosol Sci
While dry powder aerosol formulations offer a number of advantages, their use in children is often limited due to poor lung delivery efficiency and difficulties with consistent dry powder inhaler (DPI) usage. Both of these challenges can be attribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c16ea04176c434d95ac1f5012161a38
https://europepmc.org/articles/PMC7945982/
https://europepmc.org/articles/PMC7945982/