Zobrazeno 1 - 10
of 728
pro vyhledávání: '"P. Wicki"'
Autor:
Vollenweider, Michael, Schürch, Manuel, Rohrer, Chiara, Gut, Gabriele, Krauthammer, Michael, Wicki, Andreas
Precision medicine has the potential to tailor treatment decisions to individual patients using machine learning (ML) and artificial intelligence (AI), but it faces significant challenges due to complex biases in clinical observational data and the h
Externí odkaz:
http://arxiv.org/abs/2410.00509
Autor:
Schürch, Manuel, Boos, Laura, Heinzelmann-Schwarz, Viola, Gut, Gabriele, Krauthammer, Michael, Wicki, Andreas, Consortium, Tumor Profiler
AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes. New technolo
Externí odkaz:
http://arxiv.org/abs/2402.12190
Autor:
Carina Lotz-Jenne, Roland Lange, Sylvaine Cren, Geoffroy Bourquin, Laksmei Goglia, Thierry Kimmerlin, Micha Wicki, Manon Müller, Nadia Artico, Sabine Ackerknecht, Philippe Pfaff, Christoph Joesch, Aengus Mac Sweeney
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Tryptophan-2,3-dioxygenase (TDO2) and indoleamine-2,3-dioxygenase (IDO1) are structurally distinct heme enzymes that catalyze the conversion of L-tryptophan to N-formyl-kynurenine, and play important roles in metabolism, inflammation, and tu
Externí odkaz:
https://doaj.org/article/3e1980a3ec7c40e68c87ab5aff77895f
Autor:
Rebekka Wegmann, Ximena Bonilla, Ruben Casanova, Stéphane Chevrier, Ricardo Coelho, Cinzia Esposito, Joanna Ficek-Pascual, Sandra Goetze, Gabriele Gut, Francis Jacob, Andrea Jacobs, Jack Kuipers, Ulrike Lischetti, Julien Mena, Emanuela S. Milani, Michael Prummer, Jacobo Sarabia Del Castillo, Franziska Singer, Sujana Sivapatham, Nora C. Toussaint, Oliver Vilinovszki, Mattheus H. E. Wildschut, Tharshika Thavayogarajah, Disha Malani, The TumorProfiler Consortium, Rudolf Aebersold, Marina Bacac, Niko Beerenwinkel, Christian Beisel, Bernd Bodenmiller, Viola Heinzelmann-Schwarz, Viktor H. Koelzer, Mitchell P. Levesque, Holger Moch, Lucas Pelkmans, Gunnar Rätsch, Markus Tolnay, Andreas Wicki, Bernd Wollscheid, Markus G. Manz, Berend Snijder, Alexandre P. A. Theocharides
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Deep single-cell multi-omic profiling offers a promising approach to understand and overcome drug resistance in relapsed or refractory (rr) acute myeloid leukemia (AML). Here, we combine single-cell ex vivo drug profiling (pharmacoscopy) wit
Externí odkaz:
https://doaj.org/article/d909919fc46044dd87b6ffb2a1e8a194
Autor:
Marine Wicki, Daniel J. Brown, Phillip M. Gurman, Jérôme Raoul, Andrés Legarra, Andrew A. Swan
Publikováno v:
Genetics Selection Evolution, Vol 56, Iss 1, Pp 1-18 (2024)
Abstract Background The Dohne Merino sheep was introduced to Australia from South Africa in the 1990s. It was primarily used in crosses with the Merino breed sheep to improve on attributes such as reproduction and carcass composition. Since then, thi
Externí odkaz:
https://doaj.org/article/ebca58dbd8424e7a9c1d939f237a1395
Autor:
Benoit J Van den Eynde, Maryam Ahmad, James McAuliffe, Laurine Noblecourt, Ramiro Andrei Ramirez-Valdez, Vinnycius Pereira-Almeida, Carol Sze Ki Leung, Vincent Stroobant, Amanda Wicki, Silvia Panetti, Emily Steffke, Yushu Hu, Shi Yu William Guo, Julie Lesenfants, Vineethkrishna Chandrasekar, Nathalie Vigneron
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background Melanoma antigen gene (MAGE)-type antigens are promising targets for cancer immunotherapy as they are expressed in cancer cells but not in normal tissues, except for male germline cells. The mouse P1A antigen shares this MAGE-type expressi
Externí odkaz:
https://doaj.org/article/09e8625b83a644fea1c0f18984102032
Autor:
Héctor A. Levipan, L. Felipe Opazo, Sara Arenas-Uribe, Hernán Wicki, Francisca Marchant, Lennin Florez-Leiva, Ruben Avendaño-Herrera
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Microbial life forms are among the most ubiquitous on Earth, yet many remain understudied in Caribbean estuaries. We report on the prokaryote community composition of the Urabá Estuary in the Colombian Caribbean using 16S rRNA gene-transcri
Externí odkaz:
https://doaj.org/article/e303aa8f10254781beb76dd95cb41cd8
Autor:
Ludwik Wicki, Aleksandra Wicka
Publikováno v:
Annals of the Polish Association of Agricultural and Agribusiness Economists, Vol XXVI, Iss 2, Pp 199-213 (2024)
In the context of agriculture, numerous significant long-term trends are emerging. Some of these pose threats to farm operations. They can be categorized as threats related to pressure to achieve climate and environmental targets under emission reduc
Externí odkaz:
https://doaj.org/article/c34039dcc05e49c499abb5e2cea16315
Autor:
Flavio Wicki, Tatiana Latychevskaia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract In this study, we propose a new method for single-shot, high-resolution lensless imaging called double-slit holography. This technique combines the properties of in-line and off-axis holography in one single-shot measurement using the simple
Externí odkaz:
https://doaj.org/article/0a0147fd769a434cbb711bff8e7ff29a
Autor:
Danielle Vienneau, Benedikt Wicki, Benjamin Flückiger, Beat Schäffer, Jean Marc Wunderli, Martin Röösli
Publikováno v:
Environmental Health, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Background Long-term exposure to transportation noise is related to cardio-metabolic diseases, with more recent evidence also showing associations with diabetes mellitus (DM) incidence. This study aimed to evaluate the association between tr
Externí odkaz:
https://doaj.org/article/6d9e18937de84e07941fb7215e2f41e8