Zobrazeno 1 - 10
of 3 656
pro vyhledávání: '"P. Westra"'
Autor:
Nicotra, Davide, Martinez, Miriam Lucio, de Vries, Jacco Andreas, Merk, Marcel, Driessens, Kurt, Westra, Ronald Leonard, Dibenedetto, Domenica, Pérez, Daniel Hugo Cámpora
High-energy physics is facing increasingly computational challenges in real-time event reconstruction for the near-future high-luminosity era. Using the LHCb vertex detector as a use-case, we explore a new algorithm for particle track reconstruction
Externí odkaz:
http://arxiv.org/abs/2308.00619
Autor:
Jiafei Wu, Victoria Palasantzas, Sergio Andreu-Sánchez, Torsten Plösch, Sam Leonard, Shuang Li, Marc Jan Bonder, Harm-Jan Westra, Joyce van Meurs, Mohsen Ghanbari, Lude Franke, Alexandra Zhernakova, Jingyuan Fu, Joanne A. Hoogerland, Daria V. Zhernakova
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background The plasma metabolome reflects the physiological state of various biological processes and can serve as a proxy for disease risk. Plasma metabolite variation, influenced by genetic and epigenetic mechanisms, can also affect the ce
Externí odkaz:
https://doaj.org/article/9ba2686e25cc4689806e48f764522f07
Autor:
Carlos G. Urzúa-Traslaviña, Tijs van Lieshout, Floranne Boulogne, Kevin Domanegg, Mahmoud Zidan, Olivier B. Bakker, Annique Claringbould, Jeroen de Ridder, Wilbert Zwart, Harm-Jan Westra, Patrick Deelen, Lude Franke
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background The genetic background of cancer remains complex and challenging to integrate. Many somatic mutations within genes are known to cause and drive cancer, while genome-wide association studies (GWAS) of cancer have revealed many germ
Externí odkaz:
https://doaj.org/article/87d4375406f84fe0ab53a48e271de9a9
Autor:
Postema, Jasper Johannes, Bonizzi, Pietro, Koekoek, Gideon, Westra, Ronald L., Kokkelmans, Servaas J. J. M. F.
Publikováno v:
AVS Quantum Sci. 5, 023803 (2023)
Classical data analysis requires computational efforts that become intractable in the age of Big Data. An essential task in time series analysis is the extraction of physically meaningful information from a noisy time series. One algorithm devised fo
Externí odkaz:
http://arxiv.org/abs/2212.08831
Autor:
Alejandra Zepeda-Echavarria, Niek C. M. Ratering Arntz, Albert H. Westra, Leonard J. van Schelven, Froukje E. Euwe, Herke Jan Noordmans, Melle Vessies, Rutger R. van de Leur, Rutger J. Hassink, Thierry X. Wildbergh, Rien van der Zee, Pieter A. Doevendans, René van Es, Joris E. N. Jaspers
Publikováno v:
Frontiers in Digital Health, Vol 6 (2024)
Cardiovascular diseases (CVDs) are a global burden that requires attention. For the detection and diagnosis of CVDs, the 12-lead ECG is a key tool. With technological advancements, ECG devices are becoming smaller and available for home use. Most of
Externí odkaz:
https://doaj.org/article/fe9fbbffdbda4b429024c28947c16e3f
Autor:
Bas P. H. Adriaansen, Agustini Utari, Dineke Westra, Achmad Zulfa Juniarto, Mahayu Dewi Ariani, Annastasia Ediati, Mariska A. M. Schröder, Paul N. Span, Fred C. G. J. Sweep, Stenvert L. S. Drop, Sultana M. H. Faradz, Antonius E. van Herwaarden, Hedi L. Claahsen – van der Grinten
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionCongenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) or 11-hydroxylase deficiency (11OHD) is characterized by underproduction of cortisol and overproduction of adrenal androgens. These androgens lead to a variable
Externí odkaz:
https://doaj.org/article/48f6cb3fd87c455992e4f56a2d178f4c
Autor:
C. Wasko, S. Westra, R. Nathan, A. Pepler, T. H. Raupach, A. Dowdy, F. Johnson, M. Ho, K. L. McInnes, D. Jakob, J. Evans, G. Villarini, H. J. Fowler
Publikováno v:
Hydrology and Earth System Sciences, Vol 28, Pp 1251-1285 (2024)
In response to flood risk, design flood estimation is a cornerstone of planning, infrastructure design, setting of insurance premiums, and emergency response planning. Under stationary assumptions, flood guidance and the methods used in design flood
Externí odkaz:
https://doaj.org/article/675218290c64453e9390cebcf297539a
Autor:
Taehyeung Kim, Marta Martínez-Bonet, Qiang Wang, Nicolaj Hackert, Jeffrey A. Sparks, Yuriy Baglaenko, Byunghee Koh, Roxane Darbousset, Raquel Laza-Briviesca, Xiaoting Chen, Vitor R. C. Aguiar, Darren J. Chiu, Harm-Jan Westra, Maria Gutierrez-Arcelus, Matthew T. Weirauch, Soumya Raychaudhuri, Deepak A. Rao, Peter A. Nigrovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Fine-mapping and functional studies implicate rs117701653, a non-coding single nucleotide polymorphism in the CD28/CTLA4/ICOS locus, as a risk variant for rheumatoid arthritis and type 1 diabetes. Here, using DNA pulldown, mass spectrometry,
Externí odkaz:
https://doaj.org/article/89591f74d78449f789de95d34d7df2b8
Autor:
Florian Zeevat, Joost J. M. Simons, Tjalke A. Westra, Jan C. Wilschut, Nina M. van Sorge, Cornelis Boersma, Maarten J. Postma
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 3, Pp 481-499 (2024)
Abstract Introduction Invasive meningococcal disease (IMD) caused by Neisseria meningitidis is a rapidly progressing, rare disease that often presents as meningitis or sepsis. It mostly affects infants and adolescents, with high fatality rates or lon
Externí odkaz:
https://doaj.org/article/e533bfc6adb84078b0470a511629ab13
Autor:
Martijn Vochteloo, Patrick Deelen, Britt Vink, BIOS Consortium, Ellen A. Tsai, Heiko Runz, Sergio Andreu-Sánchez, Jingyuan Fu, Alexandra Zhernakova, Harm-Jan Westra, Lude Franke
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Expression quantitative trait loci (eQTL) offer insights into the regulatory mechanisms of trait-associated variants, but their effects often rely on contexts that are unknown or unmeasured. We introduce PICALO, a method for hidden variable
Externí odkaz:
https://doaj.org/article/1bb030c23f7a471a97ee8771da5fe1e3