Zobrazeno 1 - 10 of 71 pro vyhledávání: '"P. W. Schiller"'
1
Akademický článek
Use of Pre- and Intensified Postprocedural Physiotherapy in Patients with Symptomatic Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement Study (the 4P-TAVR Study)
Autor: M. Weber, U. Klein, A. Weigert, W. Schiller, V. Bayley-Ezziddin, D. C. Wirtz, A. Welz, N. Werner, E. Grube, G. Nickenig, J.-M. Sinning, A. Ghanem
Publikováno v: Journal of Interventional Cardiology, Vol 2021 (2021)
Background. Physiotherapy prior to open-heart surgery lowers the rate of pneumonia and length of the hospital stay. Pneumonia is a major contributor to short-term mortality following transcatheter aortic valve replacement (TAVR). Hence, we hypothesiz
Externí odkaz: https://doaj.org/article/ffdd9ebc07cd40218cf47159605a6351
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2
Akademický článek
Strengthening peptide-based drug activity with novel glyconanoparticle.
Autor: Jordan D Lewicky, Alexandrine L Martel, Nya L Fraleigh, Amanda Boraman, Thi M-D Nguyen, Peter W Schiller, Tze Chieh Shiao, René Roy, Hoang-Thanh Le
Publikováno v: PLoS ONE, Vol 13, Iss 9, p e0204472 (2018)
The therapeutic application of peptide-based drugs is significantly limited by the rapid proteolytic degradation that occurs when in blood. Encapsulation of these peptide structures within a delivery system, such as liposomes, can greatly improve bot
Externí odkaz: https://doaj.org/article/84e1b41a2ce54f7cad73c25d5a19d4af
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3
The Cardiovascular and Renal Effects of the Potent and Highly Selective μ Opioid Agonist [Dmt1]DALDA
Autor: P W Schiller, Marek Jankowski, Jolanta Gutkowska, Suhayla Mukaddam-Daher
Publikováno v: Journal of Cardiovascular Pharmacology. 44:651-658
The cardiovascular and renal effects of a mu opioid agonist, [Dmt]DALDA, were studied in conscious Sprague-Dawley rats. During the first hour postinjection, [Dmt]DALDA (0.025-250 microg/rat, IV) evoked a dose-dependent diuresis. The dose of 2.5 micro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d45a7a5e0ce70386256d838f4fafe4a
https://doi.org/10.1097/00005344-200412000-00005
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4
A novel cis-peptide bond motif inducing beta-turn type VI. The synthesis of enkephalin analogues modified with 4-aminopyroglutamic acid
Autor: K Kaczmarek, M Kaleta, N N Chung, P W Schiller, J Zabrocki
Publikováno v: Acta Biochimica Polonica. 48:1159-1163
A new pathway leading to a mixture of four isomers of 4-aminopyroglutamic acid is described. Michael type addition of Z-deltaAla-OMe to enolates prepared from acylaminomalonates, followed by hydrolysis and decarboxylation give protected 4-aminopyrogl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bc6ba913f81ad04719b137b23aff28d
https://doi.org/10.18388/abp.2001_3884
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8
Synthesis, conformational analysis, and biological activity of opioid peptide analogs containing side chain fluorinated amino acids
Autor: N. N. Chung, Klaus Burger, Michael Thormann, P. W. Schiller, Hans-Jörg Hofmann, Norbert Sewald, M. Gussmann, Dirk Winkler
Publikováno v: Peptide Science — Present and Future ISBN: 0792352718
Several peptides isolated from mammalian brain are endogenous agonists of the opiate receptors (μ, δ, and κ ). They are of current interest in medicinal chemistry and neurobiology because of their mediation of strong analgesic effects. New analogu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4c9427db0a6a0925582a4505e7e53fc
https://doi.org/10.1007/0-306-46864-6_156
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9
Type and location of fluorescent probes incorporated into the potent mu-opioid peptide [Dmt]DALDA affect potency, receptor selectivity and intrinsic efficacy
Autor: P W, Schiller, I, Berezowska, G, Weltrowska, H, Chen, C, Lemieux, N N, Chung
Publikováno v: The journal of peptide research : official journal of the American Peptide Society. 65(6)
The dermorphin-derived tetrapeptide H-Dmt-d-Arg-Phe-Lys-NH(2) (Dmt = 2',6'-dimethyltyrosine) ([Dmt(1)]DALDA) is a highly potent and selective mu-opioid agonist capable of crossing the blood-brain barrier and producing a potent, centrally mediated ana
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::650ad9e3c891408e4f4a203c9bdc4d85
https://pubmed.ncbi.nlm.nih.gov/15885115
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10
Cyclic enkephalin analogs containing various para-substituted phenylalanine derivatives in place of Tyr1 are potent opioid agonists
Autor: G, Weltrowska, C, Lemieux, N N, Chung, P W, Schiller
Publikováno v: The journal of peptide research : official journal of the American Peptide Society. 65(1)
The cyclic enkephalin analog H-Tyr-c[D-Cys-Gly-Phe(pNO(2))-D-Cys]NH(2) is a highly potent opioid agonist with IC(50)s of 35 pm and 19 pm in the guinea-pig ileum (GPI) and mouse vas deferens (MVD) assays, respectively. The Phe(1)-analog of this peptid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c834728a9d086a6013b18446895e029
https://pubmed.ncbi.nlm.nih.gov/15686532
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