Výsledky vyhledávání - "P. W. Runstadler"

Medium Optimization for Perfused Culture to Provide High Product Titer

Autor: R. H. L. Pang, S. S. Ozturk, M. W. Young, N. G. Ray, A. S. Tung, P. W. Runstadler

Publikováno v: Animal Cell Technology: Basic & Applied Aspects ISBN: 9780792324775

Culture productivity and product titer can significantly affect the economics of large-scale production of biotherapeutics. Bioreactor space-time productivity is determined by cell density and cell-specific productivity, while product titer is determ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26871e3300ddf85bff6657b5bcb199c1
https://doi.org/10.1007/978-94-011-2044-9_52

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An Evaluation of Hybridoma Cell-Specific Productivity: Perfused Immobilized, Continuous Suspension, and Batch Suspension Cultures

Autor: P. W. Runstadler, S. S. Ozturk, N. G. Ray

Publikováno v: Animal Cell Technology: Basic & Applied Aspects ISBN: 9780792318828

Verax Corporation has pioneered the use of natural collagen macroporous microcarriers (Microspheres) for the small and large-scale cultivation of animal cells, both attachment preferred and suspension cells. Collagen Microspheres containing cells are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e91c55b6af966b4e1318fc90799cc1b
https://doi.org/10.1007/978-94-011-2844-5_8

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Optimization of the microenvironment for mammalian cell culture in flexible collagen microspheres in a fluidized-bed bioreactor

Autor: J N, Vournakis, P W, Runstadler

Publikováno v: Biotechnology (Reading, Mass.). 17

Flexible, three-dimensional, collagen Microspheres have been developed to actively promote a natural, optimal microenvironment for large-scale tissue culture of mammalian cells. The transport of nutrients into and cell products out of the Microsphere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8d0bf4a5b04a63bad943fc81b08b3569
https://pubmed.ncbi.nlm.nih.gov/2049545

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ENHANCED PRODUCTIVITY OF HYBRIDOMA AND RECOMBINANT CHO CELL CULTURES BY PLURONIC F-68 AND OTHER MEDIUM COMPONENTS, AND BY INCREASED PERFUSION RATES, IN FLUIDIZED-BED BIOREACTORS

Autor: P. W. Runstadler, A. S. Tung, J. N. Vournakis, N. G. Ray

Hybridoma and Chinese Hamster Ovary (CHO) cells are cultured in continuous fluidized-bed bioreactors. Cells are immobilized in porous, weighted collagen microspheres which are suspended in the bioreactor by the recycling of culture liquid. This paper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fe96cafaad372678fa8388968146cc2
https://doi.org/10.1016/b978-0-7506-1103-9.50095-0

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Continuous culture with macroporous matrix, fluidized bed systems

Autor: P W, Runstadler, A S, Tung, E G, Hayman, N G, Ray, J G, Sample, D E, DeLucia

Publikováno v: Bioprocess technology. 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::297155a2d0b4a0580a954ad7211f308d
https://pubmed.ncbi.nlm.nih.gov/1367065

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Continuous cell cultures in fluidized-bed bioreactors. Cultivation of hybridomas and recombinant Chinese hamster ovary cells immobilized in collagen microspheres

Autor: N. G. Ray, J. N. Vournakis, E. G. Hayman, P. W. Runstadler, A. S. Tung

Publikováno v: Annals of the New York Academy of Sciences. 589

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70c8e55139a5a676b19526977562d1d
https://pubmed.ncbi.nlm.nih.gov/2357029

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Effect of Specific Heat Ratio, Impeller Tip Running Clearance, and Compressor Insulation on High-Pressure-Ratio Centrifugal Compressor Modeling

Autor: P. W. Runstadler, J. A. Block

Publikováno v: Journal of Fluids Engineering. 97:174-179

Results are displayed which show the effect of gas specific heat ratio, impeller tip running clearance, and compressor insulation on modeling of a high-pressure-ratio compressor’s performance. The data were obtained using a low-speed-of-sound gas a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5f5901c091ca1d6aed1d251f4b800a8
https://doi.org/10.1115/1.3447249

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Discussion: 'Performance of Three Vaned Radial Diffusers With Swirling Transonic Flow' (Baghdadi, S., and McDonald, A. T., 1975, ASME J. Fluids Eng., 97, pp. 155–160)

Autor: P. W. Runstadler

Publikováno v: Journal of Fluids Engineering. 97:164-168

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edf72a7e454de6db4bb7954ee2a43adf
https://doi.org/10.1115/1.3447246

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First-Order Pump Surge Behavior

Autor: P. W. Runstadler, P. H. Rothe

Publikováno v: Journal of Fluids Engineering. 100:459-466

This paper presents the results of an empirical study undertaken to assess the appropriateness and applicability of a simple, analytical model of pump-piping system flow instability. The analysis is used to describe behavior actually observed in a we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9381119a0fe33e98102bd1addde9a56b
https://doi.org/10.1115/1.3448708

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An Experimental Study of Surge in Centrifugal Compressors

Autor: P. W. Runstadler, R. C. Dean, Kosuke Toyama

Publikováno v: Journal of Fluids Engineering. 99:115-124

Results of high-response measurements in a high-pressure-ratio centrifugal compressor during surge operation are presented. The interpretation of the data provides improved understanding of the flow mechanism of surge and the phenomena which apparent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ab62c31390d66ebaa9f352a81f5408a
https://doi.org/10.1115/1.3448506

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