Zobrazeno 1 - 10
of 19
pro vyhledávání: '"P. W. McConnell"'
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 28, Iss , Pp 1-8 (2023)
Introduction: Determination of folate insufficiency is of considerable interest given its importance in fetal development and red blood cell formation; however, access to blood tests may be limited due to the requirement for phlebotomy as well as con
Externí odkaz:
https://doaj.org/article/98daeb5207414367a02876bb46d948a5
Autor:
Sruthi Santhanam, Cheng Chen, Byeongtaek Oh, Kelly W. McConnell, Matine M. Azadian, Jainith J. Patel, Emily E. Gardner, Yuji Tanabe, Ada S. Y. Poon, Paul M. George
Publikováno v:
Advanced Electronic Materials, Vol 9, Iss 10, Pp n/a-n/a (2023)
Abstract Effective stroke recovery therapeutics remain limited. Stem cell therapies have yielded promising results, but the harsh ischemic environment of the post‐stroke brain reduces their therapeutic potential. Previously, a conductive polymer sy
Externí odkaz:
https://doaj.org/article/eff0ff77c57a4766ad822d4dc37eda0c
Autor:
Megan Mayer, David B. Badesch, Kelly H. Nielsen, Steven Kawut, Todd Bull, John J. Ryan, Jeffrey Sager, Sula Mazimba, Anna Hemnes, James Klinger, James Runo, John W. McConnell, Teresa De Marco, Murali M. Chakinala, Delphine Yung, Jean Elwing, Adolfo Kaplan, Rahul Argula, Raymond Pomponio, Ryan Peterson, Peter Hountras
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract To better understand the impact of the COVID‐19 pandemic on the care of patients with pulmonary hypertension, we conducted a retrospective cohort study evaluating health insurance status, healthcare access, disease severity, and patient re
Externí odkaz:
https://doaj.org/article/2e5ecf9698454f89883f1139645ab4b7
Autor:
Byeongtaek Oh, Sruthi Santhanam, Matine Azadian, Vishal Swaminathan, Alex G. Lee, Kelly W. McConnell, Alexa Levinson, Shang Song, Jainith J. Patel, Emily E. Gardner, Paul M. George
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Paul George and colleagues developed a conductive polymer system to enable stem cell delivery and electrical modulation in vivo. Employing this system improved functional stroke recovery in rodents and identified important repair pathways.
Externí odkaz:
https://doaj.org/article/e34baf38de8b485a92c16b327f8a2cce
Autor:
Enrico de Belen, John W. McConnell, Jean M. Elwing, David Paculdo, Ian Cabaluna, Jörg Linder, John W. Peabody
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 2 (2023)
Background Diagnosis of pulmonary hypertension (PH) is often delayed or missed, leading to disease progression and missed treatment opportunities. In this study, we measured variation in care provided by board‐certified cardiologists and pulmonolog
Externí odkaz:
https://doaj.org/article/cad3154eeda147b18bd0b88414a89828
Autor:
Vallerie V. McLaughlin, Richard Channick, Nick H. Kim, Robert P. Frantz, John W. McConnell, Lana Melendres‐Groves, Chad Miller, Ashwin Ravichandran, Josanna Rodriguez‐Lopez, Monika Brand, Sandrine Leroy, Graham Wetherill, Kelly M. Chin
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 4, Pp n/a-n/a (2022)
Abstract Macitentan is an oral endothelin receptor antagonist for the management of pulmonary arterial hypertension (PAH). The OPsumit® USers Registry (OPUS) and the OPsumit® Historical USers cohort (OrPHeUS) medical chart review provide real‐wor
Externí odkaz:
https://doaj.org/article/1ae0250ff48848e6abac30f59f11ea5e
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S2, Pp 7-16 (2019)
Abstract Background Several methods to handle data generated from bottom-up proteomics via liquid chromatography-mass spectrometry, particularly for peptide-centric quantification dealing with post-translational modification (PTM) analysis like rever
Externí odkaz:
https://doaj.org/article/1e7ef4188c3649d0af4169d4aa58b3d0
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Two oral medications targeting the prostacyclin pathway are available to treat pulmonary arterial hypertension in the United States: oral treprostinil and selexipag. We compared real-world hospitalization in patients receiving these medications. A re
Externí odkaz:
https://doaj.org/article/7dd8fa23021c4d9db3ce6b84225325b5
Autor:
Hussam J. AL-barakati, Evan W. McConnell, Leslie M. Hicks, Leslie B. Poole, Robert H. Newman, Dukka B. KC
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Protein S-sulfenylation, which results from oxidation of free thiols on cysteine residues, has recently emerged as an important post-translational modification that regulates the structure and function of proteins involved in a variety of ph
Externí odkaz:
https://doaj.org/article/a2f299fb10184e2fa23fde2539f4dae7
Publikováno v:
Redox Biology, Vol 17, Iss , Pp 35-46 (2018)
Post-translational modifications (PTMs) are covalent modifications to protein residues which may alter both conformation and activity, thereby modulating signaling and metabolic processes. While PTMs have been largely investigated independently, exam
Externí odkaz:
https://doaj.org/article/da519255be5a470795977015b230d2dd