Zobrazeno 1 - 10
of 74
pro vyhledávání: '"P. W. Laird"'
Autor:
Diljeet Kaur, Sol Moe Lee, David Goldberg, Nathan J. Spix, Toshinori Hinoue, Hong-Tao Li, Varun B. Dwaraka, Ryan Smith, Hui Shen, Gangning Liang, Nicole Renke, Peter W. Laird, Wanding Zhou
Publikováno v:
Epigenetics Communications, Vol 3, Iss 1, Pp 1-15 (2023)
Abstract Infinium Methylation BeadChips are widely used to profile DNA cytosine modifications in large cohort studies for reasons of cost-effectiveness, accurate quantification, and user-friendly data analysis in characterizing these canonical epigen
Externí odkaz:
https://doaj.org/article/91917cef90fd4805b040cfcf02235f3b
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
DNA methylation loss has been observed in aging tissues and cancers for decades. Researchers from Van Andel Institute have now provided experimental evidence that this process is directly driven by cell division.
Externí odkaz:
https://doaj.org/article/e186c199ec3148bfa0903428332522e3
Autor:
Tomasz K. Baginski, Karthik Veeravalli, Rebekah McKenna, Christopher Williams, Katherine Wong, Christina Tsai, Daniel Hewitt, Karthik Mani, Michael W. Laird
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background Escherichia coli (E. coli) is a promising host for production of recombinant proteins (including antibodies and antibody fragments) that don’t require complex post-translational modifications such as glycosylation. During manufa
Externí odkaz:
https://doaj.org/article/4bf0565975cc45ce9f5a2e9b90ff2c0d
Autor:
Sergiu A. Lucaciu, Rhett Figliuzzi, Ruth Neumann, Samina Nazarali, Luigi Del Sordo, Stephanie E. Leighton, Alexandra Hauser, Qing Shao, Danielle Johnston, Donglin Bai, Dale W. Laird
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Epidermal keratinocytes are enriched with at least nine connexins that are key regulators of epidermal homeostasis. The role of Cx30.3 in keratinocytes and epidermal health became evident when fourteen autosomal dominant mutations in the Cx30.3-encod
Externí odkaz:
https://doaj.org/article/d9e21486100448b4bd878473cefb2d46
Autor:
Nyasha Chambwe, Rosalyn W. Sayaman, Donglei Hu, Scott Huntsman, Anab Kemal, Samantha Caesar-Johnson, Jean C. Zenklusen, Elad Ziv, Rameen Beroukhim, Andrew D. Cherniack, Jian Carrot-Zhang, Ashton C. Berger, Seunghun Han, Matthew Meyerson, Jeffrey S. Damrauer, Katherine A. Hoadley, Ina Felau, John A. Demchok, Michael K.A. Mensah, Roy Tarnuzzer, Zhining Wang, Liming Yang, Theo A. Knijnenburg, A. Gordon Robertson, Christina Yau, Christopher Benz, Kuan-lin Huang, Justin Y. Newberg, Garrett M. Frampton, R. Jay Mashl, Li Ding, Alessandro Romanel, Francesca Demichelis, Wanding Zhou, Peter W. Laird, Hui Shen, Christopher K. Wong, Joshua M. Stuart, Alexander J. Lazar, Xiuning Le, Ninad Oak
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101586- (2022)
Summary: Differential mRNA expression between ancestry groups can be explained by both genetic and environmental factors. We outline a computational workflow to determine the extent to which germline genetic variation explains cancer-specific molecul
Externí odkaz:
https://doaj.org/article/58eb09142b5d45b991b34126ef4e9377
Autor:
Hajar Shayesteh, Damian W. Laird, Leonie J. Hughes, Mohammad A. Nematollahi, Amin Mirshamsi Kakhki, Navid R. Moheimani
Publikováno v:
BioTech, Vol 12, Iss 3, p 49 (2023)
Microalgae can treat waste streams containing elevated levels of organic carbon and nitrogen. This process can be economically attractive if high value products are created simultaneously from the relatively low-cost waste stream. Co-production of tw
Externí odkaz:
https://doaj.org/article/66b2a6b3afc3429a889bc679b5ab0af1
Autor:
Bertrand Eardly, Wan Adnawani Meor Osman, Julie Ardley, Jaco Zandberg, Margaret Gollagher, Peter van Berkum, Patrick Elia, Dora Marinova, Rekha Seshadri, T. B. K. Reddy, Natalia Ivanova, Amrita Pati, Tanja Woyke, Nikos Kyrpides, Matthys Loedolff, Damian W. Laird, Wayne Reeve
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Although Medicago sativa forms highly effective symbioses with the comparatively acid-sensitive genus Ensifer, its introduction into acid soils appears to have selected for symbiotic interactions with acid-tolerant R. favelukesii strains. Rhizobium f
Externí odkaz:
https://doaj.org/article/8ecd4a99b66b41c8b53833026dda8f26
Autor:
Jason N. Crosson, Sanjana Kuthyar, Jessica G. Shantha, Matthew R. Debiec, Philip W. Laird, Cindy S. Hwang, Hans E. Grossniklaus, Steven Yeh
Publikováno v:
International Journal of Retina and Vitreous, Vol 6, Iss 1, Pp 1-5 (2020)
Abstract Background The cases discussed highlight the atypical presentation and diagnostic dilemmas of toxoplasmosis with fulminant retinal necrosis and the potentially devastating visual outcomes of toxoplasma chorioretinitis following local cortico
Externí odkaz:
https://doaj.org/article/79f0665fbabb4afdb6e6322d4380baf7
Autor:
Jian Carrot-Zhang, Seunghun Han, Wanding Zhou, Jeffrey S. Damrauer, Anab Kemal, Andrew D. Cherniack, Rameen Beroukhim, Ashton C. Berger, Matthew Meyerson, Katherine A. Hoadley, Ina Felau, Samantha Caesar-Johnson, John A. Demchok, Michael K.A. Mensah, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Nyasha Chambwe, Theo A. Knijnenburg, A. Gordon Robertson, Christina Yau, Christopher Benz, Kuan-lin Huang, Justin Newberg, Garret Frampton, R. Jay Mashl, Li Ding, Alessandro Romanel, Francesca Demichelis, Rosalyn W. Sayaman, Elad Ziv, Peter W. Laird, Hui Shen, Christopher K. Wong, Joshua M. Stuart, Alexander J. Lazar, Xiuning Le, Ninad Oak
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100766- (2021)
Summary: People of different ancestries vary in cancer risk and outcome, and their molecular differences may indicate sources of these variations. Determining the “local” ancestry composition at each genetic locus across ancestry-admixed populati
Externí odkaz:
https://doaj.org/article/57ccfed30daa47de8636a9bc5c03e2a0
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway
Autor:
Jian Carrot-Zhang, Xiaotong Yao, Siddhartha Devarakonda, Aditya Deshpande, Jeffrey S. Damrauer, Tiago Chedraoui Silva, Christopher K. Wong, Hyo Young Choi, Ina Felau, A. Gordon Robertson, Mauro A.A. Castro, Lisui Bao, Esther Rheinbay, Eric Minwei Liu, Tuan Trieu, David Haan, Christina Yau, Toshinori Hinoue, Yuexin Liu, Ofer Shapira, Kiran Kumar, Karen L. Mungall, Hailei Zhang, Jake June-Koo Lee, Ashton Berger, Galen F. Gao, Binyamin Zhitomirsky, Wen-Wei Liang, Meng Zhou, Sitapriya Moorthi, Alice H. Berger, Eric A. Collisson, Michael C. Zody, Li Ding, Andrew D. Cherniack, Gad Getz, Olivier Elemento, Christopher C. Benz, Josh Stuart, J.C. Zenklusen, Rameen Beroukhim, Jason C. Chang, Joshua D. Campbell, D. Neil Hayes, Lixing Yang, Peter W. Laird, John N. Weinstein, David J. Kwiatkowski, Ming S. Tsao, William D. Travis, Ekta Khurana, Benjamin P. Berman, Katherine A. Hoadley, Nicolas Robine, Matthew Meyerson, Ramaswamy Govindan, Marcin Imielinski
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108784- (2021)
Externí odkaz:
https://doaj.org/article/4264da604a8b4596a7e8b99d914ad26d