Zobrazeno 1 - 10
of 99
pro vyhledávání: '"P. W. Lücker"'
Publikováno v:
Alimentary Pharmacology & Therapeutics. 12:1027-1032
Background: Pantoprazole is a proton pump inhibitor characterized by a low potential to interact with the cytochrome P450 system, and linear pharmacokinetics. The recommended oral dose for treatment of acid-related diseases is 40 mg. Methods: Using a
Publikováno v:
Pharmaceutical Research. 11:151-155
The influence of a fat-rich meal on the pharmacokinetics of cyclosporine from a new oral formulation (Sandimmune Neoral) was compared in a randomized, four-way crossover study to the currently marketed formulation (Sandimmune) in 24 healthy male volu
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 25(8)
Acetylsalicylic acid (ASA) and pseudoephedrine (PSE) are often administered together for the treatment of symptoms of the common cold, i.e., nasal congestion, runny nose, sore throat and headache. Based on this fact we developed a fixed combination o
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 23(1)
The aim of this study was to determine the bioavailability of orally administered, crushed pantoprazole tablets after buffering with either 1.4% sodium hydrogencarbonate or 1600 mg magaldrate relative to the intact enteric coated pantoprazole tablet.
Publikováno v:
Arzneimittel-Forschung. 49(7)
In an open trial with 18 healthy male volunteers (21-45 years old) the effect of processed (test) and non-processed (reference) coffee samples of same origin on the gastric potential difference (GPD) was studied. Test coffee samples were processed wi
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 21(1)
The effects on intragastric p11 and gastrin secretion of once daily pantoprazole (40 mg) and a new formulation omeprazole (20 mg) in a Multiple Unit Pellet System (MUPS) were investigated during two treatment periods of 7 days each in a randomized cr
Autor:
M, Hartmann, A, Ehrlich, H, Fuder, R, Lühmann, S, Emeklibas, W, Timmer, W, Wurst, P W, Lücker
Publikováno v:
Alimentary pharmacologytherapeutics. 12(10)
Pantoprazole is a proton pump inhibitor characterized by a low potential to interact with the cytochrome P450 system, and linear pharmacokinetics. The recommended oral dose for treatment of acid-related diseases is 40 mg.Using a randomized, crossover
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 20(2)
The gastric irritation potential of orally administered coffee (150 ml) was investigated in four healthy volunteers by continuous measurement of gastric potential difference (GPD) and intragastric pH. Furthermore, serum gastrin concentrations were me
Autor:
S. S. Preisig-Flückiger, B. L. Holt, John M. Kovarik, Y. Üresin, P. W. Lücker, E A Mueller, S. Hensel
Publikováno v:
Journal of clinical pharmacology. 37(11)
Valspodar is a cyclosporine D analog used as a chemotherapy adjunct for modifying multidrug resistance. Two studies were sequentially performed to select an optimal oral formulation and to characterize selected aspects of its clinical pharmacokinetic