Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P. W. Kohnen"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 35:2591-2595
Polyaspartic Acid (PAA) protects the kidney from experimental gentamicin nephrotoxicity despite large increases in renal cortical gentamicin content. In these experiments, prominent cytoplasmic vacuoles were noted in all animals that received PAA wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c25bd6c5feb41e53087ceb7fe9b1e5
https://doi.org/10.1128/aac.35.12.2591
https://doi.org/10.1128/aac.35.12.2591
Autor:
P. W. Kohnen, S. J. Kohlhepp, David N. Gilbert, William M. Bennett, James E. Leggett, Suzanne K. Swan
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:2556-2558
It is known that daily polyaspartic acid (PAA) protects the kidney from gentamicin nephrotoxicity in a standardized rat model despite marked cortical accumulation of the aminoglycoside. The present experiments address the duration of PAA protection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5910fac5c6d0b12cd1c0836578960860
https://doi.org/10.1128/aac.36.11.2556
https://doi.org/10.1128/aac.36.11.2556
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:347-348
Polyaspartic acid (PAA) ameliorates experimental gentamicin nephrotoxicity despite marked accumulation of gentamicin in the renal cortex. The experiments described here probe the extent of PAA's nephroprotective action when increasing doses of gentam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d7a4d2c141af64a4f0ec75dbf89436
https://doi.org/10.1128/aac.37.2.347
https://doi.org/10.1128/aac.37.2.347
Autor:
S. J. Kohlhepp, D. N. Gilbert, William M. Bennett, H. C. Finkbeiner, Craig A. Wood, Donald C. Houghton, P. W. Kohnen, Jessie N. Lindsley
Publikováno v:
The Journal of infectious diseases. 159(5)
The influence of the polyamino acid polyaspartic acid (PAA) on experimental aminoglycoside nephrotoxicity was determined. PAA prevented all measured functional and pathologic evidence of gentamicin nephrotoxicity for less than or equal to 27 d of stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58a8aed6a1ca4ca6ad804bc06843024
https://pubmed.ncbi.nlm.nih.gov/2651534
https://pubmed.ncbi.nlm.nih.gov/2651534
Autor:
R S, Basler, P W, Kohnen
Publikováno v:
Archives of dermatology. 114(11)
Dark blue-black pigmentation has persisted in areas of previous acne scarring in a young woman. By histologic and electron microscopic examination, the pigment is demonstrated to represent hemosiderin. Much of the hemosiderin is lying free within mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24a2cc0522ee3fd90db81ffe48593c75
https://pubmed.ncbi.nlm.nih.gov/152613
https://pubmed.ncbi.nlm.nih.gov/152613
The antibacterial efficacies of daptomycin and vancomycin were compared in male Fischer rats with subcutaneous abscesses caused by either methicillin-susceptible Staphylococcus aureus (MSSA) or methicillin-resistant S. aureus (MRSA). The influence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e4f3bb79f8fac875f5b1ac72c81585
https://europepmc.org/articles/PMC172640/
https://europepmc.org/articles/PMC172640/
Autor:
M. O. Loveless, Donald C. Houghton, S. J. Kohlhepp, David N. Gilbert, William M. Bennett, P. W. Kohnen
Publikováno v:
The Journal of infectious diseases. 149(4)
Commercial gentamicin C is a mixture of gentamicin C1, C1a, and C2. The nephrotoxicity of each of these constituents was compared with that of the gentamicin complex. After seven days the mean creatinine level in serum was 0.8 mg/dl in rats given C2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168fe22d697ae9e962572cff7e446a45
https://pubmed.ncbi.nlm.nih.gov/6725992
https://pubmed.ncbi.nlm.nih.gov/6725992
Autor:
W J, Monteforte, P W, Kohnen
Publikováno v:
Cancer. 34(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e8fdfa08192ca9e4c956abbf8afeba6
https://pubmed.ncbi.nlm.nih.gov/4850581
https://pubmed.ncbi.nlm.nih.gov/4850581
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 21(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f1c0b518cbb7c8f1df030630ae03017
https://pubmed.ncbi.nlm.nih.gov/4187808
https://pubmed.ncbi.nlm.nih.gov/4187808
Publikováno v:
The American journal of pathology. 53(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77c68dad2058dd3165387d4312ae576a
https://pubmed.ncbi.nlm.nih.gov/4300891
https://pubmed.ncbi.nlm.nih.gov/4300891