Zobrazeno 1 - 10
of 86
pro vyhledávání: '"P. W. Angus"'
Autor:
Lakmie S. Gunarathne, Indu G. Rajapaksha, Stephen Casey, Tawar Qaradakhi, Anthony Zulli, Harinda Rajapaksha, Jonel Trebicka, Peter W. Angus, Chandana B. Herath
Publikováno v:
Hepatology Communications, Vol 6, Iss 9, Pp 2523-2537 (2022)
Abstract Splanchnic vasodilatation contributes to the development and aggravation of portal hypertension (PHT). We previously demonstrated that in cirrhosis, angiotensin‐ mediates splanchnic vasodilatation through the Mas receptor (MasR). In this s
Externí odkaz:
https://doaj.org/article/2b4d0e94c1144880adb97ad9f6f0059e
Autor:
Indu G. Rajapaksha, Lakmie S. Gunarathne, Khashayar Asadi, Ross Laybutt, Sof Andrikopoulous, Ian E. Alexander, Mathew J. Watt, Peter W. Angus, Chandana B. Herath
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1056-1072 (2022)
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease and is frequently associated with type 2 diabetes. However, there is no specific medical therapy to treat this condition. Angiotensin‐converting enzyme 2 (AC
Externí odkaz:
https://doaj.org/article/08064fce3b5743cb8a28721cf571fa86
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/ae61a946b7e84f11b268c4f4a42b6a70
Autor:
Indu G. Rajapaksha, Lakmie S. Gunarathne, Khashayar Asadi, Sharon C. Cunningham, Alexandra Sharland, Ian E. Alexander, Peter W. Angus, Chandana B. Herath
Publikováno v:
Hepatology Communications, Vol 3, Iss 12, Pp 1656-1673 (2019)
There is a large unmet need for effective therapies for cholestatic disorders, including primary sclerosing cholangitis (PSC), a disease that commonly results in liver failure. Angiotensin (Ang) II of the renin Ang system (RAS) is a potent profibroti
Externí odkaz:
https://doaj.org/article/6d5408cffc4642cfa702001e7df903ec
Akademický článek
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Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Portal hypertension (PHT) resulting from splanchnic vasodilatation is a major cause of morbidity and mortality in patients with cirrhosis. The renin-angiotensin system (RAS) plays an important role in splanchnic vasodilatation in cirrhosis. This stud
Externí odkaz:
https://doaj.org/article/2d1ae2f7325246d89459e51f70c7f226
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Sabine Klein, Chandana B Herath, Robert Schierwagen, Josephine Grace, Tom Haltenhof, Frank E Uschner, Christian P Strassburg, Tilman Sauerbruch, Thomas Walther, Peter W Angus, Jonel Trebicka
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138732 (2015)
Although in cirrhosis with portal hypertension levels of the vasoconstrictor angiotensin II are increased, this is accompanied by increased production of angiotensin (Ang)-(1-7), the endogenous ligand of the Mas receptor (MasR), which blunts hepatic
Externí odkaz:
https://doaj.org/article/84604e70b1b04408b1a92d18500c98f4
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138522 (2015)
Immunosuppressants are used ubiquitously post-liver transplantation to prevent allograft rejection. However their effects on hepatocytes are unknown. Experimental data from non-liver cells indicate that immunosuppressants may promote cell death there
Externí odkaz:
https://doaj.org/article/f61b51a8725f43a9833ddd56cd7e706a
Publikováno v:
Journal of Orthopaedic Surgery, Vol 22 (2014)
Purpose. To compare the subjective outcome of acromioclavicular joint (ACJ) reconstruction using the modified Weaver-Dunn procedure versus the Surgilig synthetic ligament. Methods. 55 patients aged 19 to 72 (mean, 42) years underwent ACJ reconstructi
Externí odkaz:
https://doaj.org/article/7f31ab6fa9604924abc087df32d2050d