Zobrazeno 1 - 10
of 76
pro vyhledávání: '"P. Vadukul"'
Publikováno v:
BJA Open, Vol 4, Iss , Pp 100061- (2022)
Externí odkaz:
https://doaj.org/article/a25c8c18382746f3abcb3213b19e1130
A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF
Autor:
Alessandra Bigi, Liliana Napolitano, Devkee M. Vadukul, Fabrizio Chiti, Cristina Cecchi, Francesco A. Aprile, Roberta Cascella
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background Amyloid-β42 (Aβ42) aggregation consists of a complex chain of nucleation events producing soluble oligomeric intermediates, which are considered the major neurotoxic agents in Alzheimer’s disease (AD). Cerebral lesions in the
Externí odkaz:
https://doaj.org/article/e31cb433d4c24d6992d739c228d88a50
Autor:
Federica Raguseo, Yiran Wang, Jessica Li, Marija Petrić Howe, Rubika Balendra, Anouk Huyghebaert, Devkee M. Vadukul, Diana A. Tanase, Thomas E. Maher, Layla Malouf, Roger Rubio-Sánchez, Francesco A. Aprile, Yuval Elani, Rickie Patani, Lorenzo Di Michele, Marco Di Antonio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases that exist on a clinico-pathogenetic spectrum, designated ALS/FTD. The most common genetic cause of ALS/FTD is expansion of the intronic hex
Externí odkaz:
https://doaj.org/article/7acb7c2915fa45d693187ddf1818d97f
Autor:
Nuria Suelves, Shirine Saleki, Tasha Ibrahim, Debora Palomares, Sebastiaan Moonen, Marta J. Koper, Céline Vrancx, Devkee M. Vadukul, Nicolas Papadopoulos, Nikenza Viceconte, Eloïse Claude, Rik Vandenberghe, Christine A. F. von Arnim, Stefan N. Constantinescu, Dietmar Rudolf Thal, Anabelle Decottignies, Pascal Kienlen-Campard
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-26 (2023)
Abstract Aging is the main risk factor for Alzheimer’s disease (AD) and other neurodegenerative pathologies, but the molecular and cellular changes underlying pathological aging of the nervous system are poorly understood. AD pathology seems to cor
Externí odkaz:
https://doaj.org/article/5f4fdaf58fee4378a6e15e3c44d2238d
Autor:
Juan Garcia-Revilla, Antonio Boza-Serrano, Yiyun Yin, Devkee Vadukul, Jesús Soldán Hidalgo, Lluís Camprubí-Ferrer, Marta Garcia Cruzado, Isak Martinsson, Oxana Klementieva, Rocío Ruiz, Francesco Aprile, Tomas Deierborg, José Luis Venero
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S412- (2023)
Externí odkaz:
https://doaj.org/article/9ea22578060f45b4a3642ce81639f5fd
Akademický článek
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Autor:
Devkee M. Vadukul, Céline Vrancx, Pierre Burguet, Sabrina Contino, Nuria Suelves, Louise C. Serpell, Loïc Quinton, Pascal Kienlen-Campard
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract A key hallmark of Alzheimer’s disease is the extracellular deposition of amyloid plaques composed primarily of the amyloidogenic amyloid-β (Aβ) peptide. The Aβ peptide is a product of sequential cleavage of the Amyloid Precursor Protein
Externí odkaz:
https://doaj.org/article/cffde72cfd7a458c9a29c038453f9d37
Autor:
Gialama, Dimitra, Vadukul, Devkee M., Thrush, Rebecca J., Radford, Sheena E., Aprile, Francesco A.
Publikováno v:
Journal of Medicinal Chemistry; 6/27/2024, Vol. 67 Issue 12, p9857-9868, 12p
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
α-Synuclein is a key protein of the nervous system, which regulates the release and recycling of neurotransmitters in the synapses. It is also involved in several neurodegenerative conditions, including Parkinson’s disease and Multiple System Atro
Externí odkaz:
https://doaj.org/article/c4b919db269444c5b2c2cdcfba9c5ff9
Akademický článek
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