Zobrazeno 1 - 10
of 30
pro vyhledávání: '"P. V. Shadrin"'
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 13, Iss 4, Pp 549-559 (2023)
Scientific relevance. The biological activity of medicinal products may vary depending on the method of production (i.e. biological or recombinant products). The widening variety of gonadotrophin preparations, the diversity of their production method
Externí odkaz:
https://doaj.org/article/538083029c8e459db4d9dde30100a43b
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 13, Iss 2-1, Pp 292-301 (2023)
In recent years, there has been a tendency to equate the results of insulin testing by physicochemical methods with its biological activity. However, it should be emphasised that the effectiveness of insulin preparations can be judged only by the rea
Externí odkaz:
https://doaj.org/article/f163b9034f6e412a91860e76804f3a9f
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 11, Iss 2, Pp 135-142 (2021)
The median lethal dose (LD50) and low lethal dose (LD10) are calculated in acute toxicity studies, as well as during specific activity assessment of some medicines. The aim of the study was to develop a procedure for using CombiStats to calculate LD5
Externí odkaz:
https://doaj.org/article/45ae5520b30d449bb6d15a3c39549b74
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 10, Iss 2, Pp 137-141 (2020)
In order to harmonise national and foreign requirements for quality control of medicinal products, a second variant of the test method, which complies with the requirements of the European Pharmacopoeia, was included into the general monograph OFS.1.
Externí odkaz:
https://doaj.org/article/d65cb3fbd066482eaf92bfd757e19757
Autor:
R. D. Syubaev, G. V. Dolgova, N. P. Neugodova, M. N. Khairetdinova, P. V. Shadrin, A. A. Mukonin
Publikováno v:
Антибиотики и Химиотерапия, Vol 56, Iss 1-2, Pp 46-50 (2020)
Externí odkaz:
https://doaj.org/article/8e5a3be9de6e4fd193f6bb488b44400b
Publikováno v:
Антибиотики и Химиотерапия, Vol 62, Iss 7-8, Pp 42-47 (2020)
The use of the LAL test as a method for determining bacterial endotoxins (BE) allows us to normalize the content of impurities causing a pyrogenic reaction in patients. Increasing the reliability and reproducibility of this method is promoted by vali
Externí odkaz:
https://doaj.org/article/07a54035c2ff4eacbe1f4de4afc1d7d1
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 9, Iss 2, Pp 85-92 (2019)
The paper considers insulin’s specific action on the patient’s body, types of insulin preparations and insulin analogues which are used for the treatment of diabetes, as well as applicable requirements for these products. It was demonstrated that
Externí odkaz:
https://doaj.org/article/8395f0d52bda4a57a231e2b9430e4ac6
Autor:
Egor S. Zadereev, Nickolai V. Shadrin
Publikováno v:
Журнал Сибирского федерального университета: Серия Биология, Vol 11, Iss 4, Pp 288-293 (2018)
Externí odkaz:
https://doaj.org/article/4f7a2b4ff9b04dd48cfa9e40116301ca
Publikováno v:
Журнал Сибирского федерального университета: Серия Биология, Vol 10, Iss 1, Pp 5-8 (2017)
Externí odkaz:
https://doaj.org/article/5b2ca52a83a7497d8b1f1e15a1ede2d5
Publikováno v:
Журнал Сибирского федерального университета: Серия Биология, Vol 10, Iss 1, Pp 114-126 (2017)
Fluctuating asymmetry (FA) of animals as a measure of ontogenetic stability is widely used in environmental bioindication. Environmental stress leads to increased levels of FA within populations. Artemia (Anostraca) is among the most primitive and an
Externí odkaz:
https://doaj.org/article/1682143a92ab4431b1fcf2ebbba8de1b