Zobrazeno 1 - 10
of 42
pro vyhledávání: '"P. V. Mitchell"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Pancreatic adenocarcinoma is one of the most aggressive and lethal forms of cancer. Chemotherapy is the primary treatment for pancreatic cancer, but resistance to the drugs used remains a major challenge. A genome-wide CRISPR interference an
Externí odkaz:
https://doaj.org/article/0a01dade22474bd7b3f5843e572dede0
Autor:
Chloe A. Stewart, Derek G. V. Mitchell, Penny A. MacDonald, Stephen H. Pasternak, Paul F. Tremblay, Elizabeth C. Finger
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Guilt is a negative emotion elicited by realizing one has caused actual or perceived harm to another person. One of guilt’s primary functions is to signal that one is aware of the harm that was caused and regrets it, an indication that the
Externí odkaz:
https://doaj.org/article/f27f3b49f7e146d5ab10ba71bde3bfed
Publikováno v:
Intervention Journal of Mental Health and Psychosocial Support in Conflict Affected Areas, Vol 22, Iss 1, Pp 64-71 (2024)
Power inequalities and structural racism are long-standing problems within the humanitarian aid sector. Staff from high income countries typically work as “international staff,” receiving better treatment than “national staff” from low- and m
Externí odkaz:
https://doaj.org/article/256bd7b9331d4b84b480b770c2e16c2f
Autor:
Nathan Hostetler, Tamara P. Tavares, Mary B. Ritchie, Lindsay D. Oliver, Vanessa V. Chen, Steven Greening, Elizabeth C. Finger, Derek G. V. Mitchell
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Youths with high levels of callous-unemotional (CU) traits and aggression are at an increased risk for developing antisocial behaviours into adulthood. In this population, neurostructural grey matter abnormalities have been observed in the p
Externí odkaz:
https://doaj.org/article/683e2be1c6a34a36a81e4822ff71d8b5
FOXQ1 recruits the MLL complex to activate transcription of EMT and promote breast cancer metastasis
Autor:
Allison V. Mitchell, Ling Wu, C. James Block, Mu Zhang, Justin Hackett, Douglas B. Craig, Wei Chen, Yongzhong Zhao, Bin Zhang, Yongjun Dang, Xiaohong Zhang, Shengping Zhang, Chuangui Wang, Heather Gibson, Lori A. Pile, Benjamin Kidder, Larry Matherly, Zhe Yang, Yali Dou, Guojun Wu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Forkhead box transcription factor, FOXQ1 is reported to promote epithelial-mesenchymal transition (EMT) and cancer metastasis. Here the authors show that FOXQ1 recruits the KMT2/MLL histone methyltransferase complex as a transcriptional coactivator t
Externí odkaz:
https://doaj.org/article/fb2c929fd9f444428d14613bbb55b90c
Autor:
Ashley Y Li, Disha P Rawal, Vanessa V Chen, Nathan Hostetler, Shannon A H Compton, Emma K Stewart, Mary B Ritchie, Derek G V Mitchell
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0284108 (2023)
Although medical masks have played a key role in decreasing the transmission of communicable disease, they simultaneously reduce the availability of nonverbal cues fundamental to social interaction. In the present study, we determined the collective
Externí odkaz:
https://doaj.org/article/e82fef85e5e641fa80c909cad0852f5f
Akademický článek
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Autor:
Marisa E. V. Mitchell, Robyn Alders, Fred Unger, Hung Nguyen-Viet, Trang Thi Huyen Le, Jenny-Ann Toribio
Publikováno v:
BMC Public Health, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The One Health concept promotes the enhancement of human, animal and ecosystem health through multi-sectorial governance support and policies to combat health security threats. In Vietnam, antimicrobial resistance (AMR) in animal
Externí odkaz:
https://doaj.org/article/9c7b5038863746408b9b0e28ba0b62cf
Autor:
Fanyan Meng, Ling Wu, Lun Dong, Allison V. Mitchell, C. James Block, Jenney Liu, Haijun Zhang, Qing Lu, Won-min Song, Bin Zhang, Wei Chen, Jiani Hu, Jian Wang, Qifeng Yang, Maik Hüttemann, Guojun Wu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Triple-negative breast cancer is an aggressive form of the disease. Here, the authors identify EGFL9 as a mediator of metastasis in TNBC through interactions with cMET.
Externí odkaz:
https://doaj.org/article/389b81394bda4d2382c09db9e9b68fc5
Autor:
Amer M. Burhan, Udunna C. Anazodo, Jun Ku Chung, Amanda Arena, Ariel Graff-Guerrero, Derek G. V. Mitchell
Publikováno v:
Behavioural Neurology, Vol 2016 (2016)
Externí odkaz:
https://doaj.org/article/56eab2ef1f9c4d4d9999a01fcf9790d4