Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P. V. Lishko"'
Autor:
Yanhe Zhao, Huafeng Wang, Caroline Wiesehoefer, Naman B. Shah, Evan Reetz, Jae Yeon Hwang, Xiaofang Huang, Tse-en Wang, Polina V. Lishko, Karen M. Davies, Gunther Wennemuth, Daniela Nicastro, Jean-Ju Chung
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Sperm motility and male fertility requires function of the CatSper calcium channels. Here, using cryo-electron tomography, authors visualize the native in-cell 3D structure and higher-order organization of the CatSper as long zigzag rows along the sp
Externí odkaz:
https://doaj.org/article/4868ad620dbe4a0693d8cadf3f45760a
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/18ebfd64053f4817a7a50a54c1b0ad5f
Autor:
Ida Björkgren, Dong Hwa Chung, Sarah Mendoza, Liliya Gabelev-Khasin, Natalie T. Petersen, Andrew Modzelewski, Lin He, Polina V. Lishko
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mammalian female fertility is defined by a successful and strictly periodic ovarian cycle, which is under the control of gonadotropins and steroid hormones, particularly progesterone and estrogen. The latter two are produced by the ovaries that are e
Externí odkaz:
https://doaj.org/article/04f75621b48245819ff3fa91eedab27c
Autor:
Liliya Gabelev Khasin, John Della Rosa, Natalie Petersen, Jacob Moeller, Lance J. Kriegsfeld, Polina V. Lishko
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
A growing number of studies point to reduced fertility upon chronic exposure to endocrine-disrupting chemicals (EDCs) such as phthalates and plasticizers. These toxins are ubiquitous and are often found in food and beverage containers, medical device
Externí odkaz:
https://doaj.org/article/2ad58fbe7e2541dea327425df9880292
Autor:
Melissa R. Miller, Samuel J. Kenny, Nadja Mannowetz, Steven A. Mansell, Michal Wojcik, Sarah Mendoza, Robert S. Zucker, Ke Xu, Polina V. Lishko
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2606-2613 (2018)
Summary: Ion channels control sperm navigation within the female reproductive tract and, thus, are critical for their ability to find and fertilize an egg. The flagellar calcium channel CatSper controls sperm hyperactivated motility and is dependent
Externí odkaz:
https://doaj.org/article/e06e7b62c2fc47d499ee0f07defe23d9
Publikováno v:
eLife, Vol 7 (2018)
Ion channels control the ability of human sperm to fertilize the egg by triggering hyperactivated motility, which is regulated by membrane potential, intracellular pH, and cytosolic calcium. Previous studies unraveled three essential ion channels tha
Externí odkaz:
https://doaj.org/article/df120cd62f3e4a219bbc178bad18b956
Autor:
Nadia R Roan, Nathallie Sandi-Monroy, Nargis Kohgadai, Shariq M Usmani, Katherine G Hamil, Jason Neidleman, Mauricio Montano, Ludger Ständker, Annika Röcker, Marielle Cavrois, Jared Rosen, Kara Marson, James F Smith, Christopher D Pilcher, Friedrich Gagsteiger, Olena Sakk, Michael O’Rand, Polina V Lishko, Frank Kirchhoff, Jan Münch, Warner C Greene
Publikováno v:
eLife, Vol 6 (2017)
Unlike other human biological fluids, semen contains multiple types of amyloid fibrils in the absence of disease. These fibrils enhance HIV infection by promoting viral fusion to cellular targets, but their natural function remained unknown. The simi
Externí odkaz:
https://doaj.org/article/5f637bd10286422c90ea408f595c4cda
Publikováno v:
eLife, Vol 2 (2013)
Mammalian spermatozoa gain competence to fertilize an oocyte as they travel through the female reproductive tract. This process is accompanied by an elevation of sperm intracellular calcium and a membrane hyperpolarization. The latter is evoked by K+
Externí odkaz:
https://doaj.org/article/d74c54255e7e46adbc06a19a2925d707
Autor:
Christopher L.R. Barratt, Sean G. Brown, S. M. Martins da Silva, S. J. Publicover, P. V. Lishko
Publikováno v:
XIIIth International Symposium on Spermatology ISBN: 9783030662912
Background: CatSper is a multi-subunit sperm-specific calcium channel that mediates the progesterone-induced increase in intracellular calcium. Evidence from CatSper subunit knock-out mouse models implicates it as essential for sperm fertilisation co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4863d8dd01e0a2791ed944aa98c0814
https://doi.org/10.1007/978-3-030-66292-9_46
https://doi.org/10.1007/978-3-030-66292-9_46
Publikováno v:
Neuroscience and Behavioral Physiology. 30:553-558
Studies of imidazole-4,5- and pyrazole-3,4-dicarboxylic acid derivatives revealed a number of new agonists and antagonists of N-methyl-D-aspartic acid (NMDA) receptors. Studies were based on whole-cell patch-clamp methods applied to rat hippocampus p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c68be5ba331e1d37f57ac66ad911c0d
https://doi.org/10.1007/bf02462614
https://doi.org/10.1007/bf02462614