Zobrazeno 1 - 10
of 15
pro vyhledávání: '"P. V. Krishna Pant"'
Autor:
Geoffrey Hom, Timothy W. Behrens, M. Ilyas Kamboh, P. V. Krishna Pant, Chao Tian, Lars Rönnblom, Iva Gunnarsson, Dennis G. Ballinger, F. Yesim Demirci, Anders A. Bengtsson, Peter K. Gregersen, Amy H. Kao, Barmak Modrek, Sharon A. Chung, Roman Kosoy, Kimberly E. Taylor, Solbritt Rantapää-Dahlqvist, Ricardo C. Ferreira, Robert R. Graham, Ward Ortmann, Susan Manzi, Sophie Garnier, Lindsey A. Criswell, Michael F. Seldin, Michelle Petri, Ann-Christine Syvänen, Annette Lee
Publikováno v:
New England Journal of Medicine. 358:900-909
Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in which the risk of disease is influenced by complex genetic and environmental contributions. Alleles of HLA-DRB1, IRF5, and STAT4 are established susceptibility genes; there i
Autor:
P. V. Krishna Pant, Wendy Filsell, Martin R. Green, Carl Jarman, Amelia Fereday, Rebecca S. Ginger, Tony Dadd, David Cox, Renee Stokowski, David A. Hinds, Frans van der Ouderaa
Publikováno v:
The American Journal of Human Genetics. 81(6):1119-1132
We have conducted a multistage genomewide association study, using 1,620,742 single-nucleotide polymorphisms to systematically investigate the genetic factors influencing intrinsic skin pigmentation in a population of South Asian descent. Polymorphis
Autor:
Laura D. Wood, D. Williams Parsons, Siân Jones, Jimmy Lin, Tobias Sjöblom, Rebecca J. Leary, Dong Shen, Simina M. Boca, Thomas Barber, Janine Ptak, Natalie Silliman, Steve Szabo, Zoltan Dezso, Vadim Ustyanksky, Tatiana Nikolskaya, Yuri Nikolsky, Rachel Karchin, Paul A. Wilson, Joshua S. Kaminker, Zemin Zhang, Randal Croshaw, Joseph Willis, Dawn Dawson, Michail Shipitsin, James K. V. Willson, Saraswati Sukumar, Kornelia Polyak, Ben Ho Park, Charit L. Pethiyagoda, P. V. Krishna Pant, Dennis G. Ballinger, Andrew B. Sparks, James Hartigan, Douglas R. Smith, Erick Suh, Nickolas Papadopoulos, Phillip Buckhaults, Sanford D. Markowitz, Giovanni Parmigiani, Kenneth W. Kinzler, Victor E. Velculescu, Bert Vogelstein
Publikováno v:
Science. 318:1108-1113
Human cancer is caused by the accumulation of mutations in oncogenes and tumor suppressor genes. To catalog the genetic changes that occur during tumorigenesis, we isolated DNA from 11 breast and 11 colorectal tumors and determined the sequences of t
Autor:
Heng Tao, Kelly A. Frazer, Dennis G. Ballinger, David Cox, Erica Beilharz, P. V. Krishna Pant
Publikováno v:
Genome Research. 16:331-339
Allelic variation of gene expression is common in humans, and is of interest because of its potential contribution to variation in heritable traits. To identify human genes with allelic expression differences, we genotype DNA and examine mRNA isolate
Autor:
Mariza de Andrade, Dennis G. Ballinger, P. V. Krishna Pant, Timothy G. Lesnick, Demetrius M. Maraganore, David Cox
Publikováno v:
The American Journal of Human Genetics. 78:1092-1094
To the Editor: In this issue, four independent research teams present new genetic association data for 13 SNPs previously reported by us to be potentially associated with Parkinson disease (PD [MIM 168600]).1 Two groups2,3 report statistically signif
Autor:
P. V. Krishna Pant, Doros N. Theodorou
Publikováno v:
Macromolecules. 28:7224-7234
A new Monte Carlo algorithm for the simulation of atomistically detailed polymer melts is presented. The method introduces connectivity relationships as variables in the description of the polymer. The connectivity of the polymer is altered in Monte
Publikováno v:
The Journal of Chemical Physics. 99:597-604
There is recent evidence that united atom CH2 Lennard‐Jones nonbonded potentials commonly used for molecular dynamics simulations for liquid polymers such as polyethylene are inadequate in some important respects. In the present work a united atom
Autor:
P. V. Krishna Pant, Richard H. Boyd
Publikováno v:
Macromolecules. 26:679-686
Molecular dynamics simulations of diffusion of a small-molecule penetrant in an amorphous polymer matrix have been carried out for the examples of methane in polyethylene (PE) and methane in polyisobutylene (PIB). Particular attention was paid to end
Autor:
P. V. Krishna Pant, Richard H. Boyd
Publikováno v:
Macromolecules. 24:6325-6331
Monte Carlo (MC) simulations of bulk polyisobutylene (PIB) were carried out at constant temperature and pression, and molecular dynamics (MD) simulations of methane diffusion in PIB and in polyethylene (PE) for comparison were made. The MC simulation
Autor:
P. V. Krishna Pant, Richard H. Boyd
Publikováno v:
Macromolecules. 24:4078-4083
A simulation of glassy polymethylene, as represented by a periodic assembly of 32 chains of 24 methylene units each, was carried out by energy minimization. The starting structures were equilibrium liquid samples taken from a constant-pressure and -t