Zobrazeno 1 - 10
of 87
pro vyhledávání: '"P. V. Giannoudis"'
Publikováno v:
Journal of Orthopaedics and Traumatology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Mesenchymal stem cells are core to bone homeostasis and repair. They both provide the progenitor cells from which bone cells are formed and regulate the local cytokine environment to create a pro-osteogenic environment. Dysregulation of thes
Externí odkaz:
https://doaj.org/article/9d6539a218514a3aaf818063946652f1
Autor:
Evangelos Daskalakis, Neelam Iqbal, Sarathkumar Loganathan, Emilio Spettoli, Giacomo Morozzi, Alberto Ballardini, Peter V. Giannoudis, Animesh Jha
Publikováno v:
Materials & Design, Vol 245, Iss , Pp 113243- (2024)
The restoration of critical-size load-bearing bone defects calls for the application of bioactive scaffolds that are regenerative, osteoconductive, and demonstrate mechanical strength comparable with natural bone. Novel hydroxyapatite (HAp) scaffolds
Externí odkaz:
https://doaj.org/article/33db2fd3bf0f43f597494771f481530a
Autor:
Andrew R. Evans, MD, Peter V. Giannoudis, BSc, MD, PhD, FRCS, FACS, Philip Leucht, MD, Todd O. McKinley, MD, Greg E. Gaski, MD, Katherine P. Frey, PhD, RN, Joseph C. Wenke, MD, Christopher Lee, MD
Publikováno v:
OTA International, Vol 7, Iss 2S (2024)
Abstract. The immune system plays an integral role in the regulation of cellular processes responsible for fracture healing. Local and systemic influences on fracture healing correlate in many ways with fracture-related outcomes, including soft tissu
Externí odkaz:
https://doaj.org/article/ec86a3853665481da2480dd6c12abea5
Autor:
Neelam Iqbal, Payal Ganguly, Lemiha Yildizbakan, El Mostafa Raif, Elena Jones, Peter V. Giannoudis, Animesh Jha
Publikováno v:
Bioengineering, Vol 11, Iss 7, p 720 (2024)
Chitosan (CS), a biopolymer, holds significant potential in bone regeneration due to its biocompatibility and biodegradability attributes. While crustacean-derived CS is conventionally used in research, there is growing interest in fungal-derived CS
Externí odkaz:
https://doaj.org/article/b40aec287e4340b6aa02e9b5882b6fb9
Publikováno v:
Biomimetics, Vol 9, Iss 6, p 308 (2024)
Biodegradable scaffolds are needed to repair bone defects. To promote the resorption of scaffolds, a large surface area is required to encourage neo-osteogenesis. Herein, we describe the synthesis and freeze-drying methodologies of ferric-ion (Fe3+)
Externí odkaz:
https://doaj.org/article/fda58a59886b4506b753a7f539c1d573
Publikováno v:
EFORT Open Reviews, Vol 8, Iss 5, Pp 264-282 (2023)
The ability to enhance fracture healing is paramount in modern orthopaedic trauma, particularly in the management of challenging cases including peri-prosthetic fractures, non-union and acute bone loss. Materials utilised in enhancing fracture healin
Externí odkaz:
https://doaj.org/article/62f594aa23b44843b14f61548029de70
Publikováno v:
EFORT Open Reviews, Vol 8, Iss 5, Pp 382-396 (2023)
Management of severely injured patients remains a challenge, characterised by a number of advances in clinical practice over the last decades. This evolution refers to all different phases of patient treatment from prehospital to the long-term rehabi
Externí odkaz:
https://doaj.org/article/6c5a44894c8e44e48cb90d213d5d96ce
Publikováno v:
Trauma Case Reports, Vol 48, Iss , Pp 100932- (2023)
We report on the treatment of a neglected displaced vertical shear pelvic fracture with functional impairment 6 months after injury in a 74-year-old woman with underlying osteoporosis. She was managed with open reduction and internal fixation and gra
Externí odkaz:
https://doaj.org/article/9eeb8964505943f69d79ae242ba04101
Publikováno v:
Trauma Case Reports, Vol 45, Iss , Pp 100823- (2023)
Tibial plateau fractures range from simple to complex. Most complex injury types are managed surgically but for some, a decision is made to treat without surgery. We present a case that was managed non-operatively but due to failure of bone union, la
Externí odkaz:
https://doaj.org/article/cd426a75db2040c1966b2f92e9a5aca9
Autor:
Bridget Jeyatha Wilson, Heather Elizabeth Owston, Neelam Iqbal, Peter V. Giannoudis, Dennis McGonagle, Hemant Pandit, Lizymol Philipose Pampadykandathil, Elena Jones, Payal Ganguly
Publikováno v:
Bioengineering, Vol 11, Iss 2, p 143 (2024)
Bone void-filling cements are one of the preferred materials for managing irregular bone voids, particularly in the geriatric population who undergo many orthopedic surgeries. However, bone marrow mesenchymal stem/stromal cells (BM-MSCs) of older-age
Externí odkaz:
https://doaj.org/article/862d10488bb5438d9927a53308ff5447