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pro vyhledávání: '"P. Thomas Vernier"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The detailed molecular mechanisms underlying the permeabilization of cell membranes by pulsed electric fields (electroporation) remain obscure despite decades of investigative effort. To advance beyond descriptive schematics to the developme
Externí odkaz:
https://doaj.org/article/21c6eeaee9d24b368b451817b016cfd4
Publikováno v:
Frontiers in Molecular Biosciences, Vol 4 (2017)
We extend the multiscale spatiotemporal heat map strategies originally developed for interpreting molecular dynamics simulations of well-structured proteins to liquids such as lipid bilayers and solvents. Our analysis informs the experimental and the
Externí odkaz:
https://doaj.org/article/e8ffb0499119451392cc2bde6d3edf3a
Akademický článek
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Publikováno v:
Biophysical Journal
Cellular effects of nanosecond-pulsed electric field exposures can be attenuated by an electric field reversal, a phenomenon called bipolar pulse cancellation. Our investigations of this phenomenon in neuroendocrine adrenal chromaffin cells show that
Publikováno v:
IEEE Transactions on Plasma Science. 48:742-748
This article was invited in order to summarize for the special edition of a Plenary Review presentation at the IEEE ICOPS/PPC meeting, June 23 2019 by M. Gundersen. It is a review of research conducted into primarily academic environments in nanoseco
Autor:
Emilie Louise Hansen, Esin Bengisu Sozer, Stefania Romeo, Stine Krog Frandsen, P Thomas Vernier, Julie Gehl
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128034 (2015)
Externí odkaz:
https://doaj.org/article/4937cacf1f5d44fb9783f6796bbd322a
Autor:
Esin B. Sozer, P. Thomas Vernier
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1861:1228-1239
Nanosecond bipolar pulse cancellation, a recently discovered phenomenon, is modulation of the effects of a unipolar electric pulse exposure by a second pulse of opposite polarity. This attenuation of biological response by reversal of the electric fi
Autor:
Josette, Zaklit, Alex, Cabrera, Aaron, Shaw, Rita, Aoun, P Thomas, Vernier, Normand, Leblanc, Gale L, Craviso
Publikováno v:
Bioelectrochemistry
Previously we reported that adrenal chromaffin cells exposed to a 5 ns, 5 MV/m pulse release the catecholamines norepinephrine (NE) and epinephrine (EPI) in a Ca(2+)-dependent manner. Here we determined that NE and EPI release increased with pulse nu
Autor:
Iurii Semenov, P. Thomas Vernier, Andrei G. Pakhomov, V. P. Kim, Maura Casciola, Esin B. Sozer, Christian W. Zemlin
Publikováno v:
Bioelectrochemistry (Amsterdam, Netherlands). 140
Exposures to short-duration, strong electric field pulses have been utilized for stimulation, ablation, and the delivery of molecules into cells. Ultrashort, nanosecond duration pulses have shown unique benefits, but they require higher field strengt
Autor:
Sourav Haldar, Joshua Zimmerberg, P. Thomas Vernier, Esin B. Sozer, Paul S. Blank, Federica Castellani
Publikováno v:
Biophys J
Although transport of molecules into cells via electroporation is a common biomedical procedure, its protocols are often based on trial and error. Despite a long history of theoretical effort, the underlying mechanisms of cell membrane electroporatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd138400a63e6196fcf21a1e2424f372
https://europepmc.org/articles/PMC7677249/
https://europepmc.org/articles/PMC7677249/