Zobrazeno 1 - 10
of 11
pro vyhledávání: '"P. T. Prendergast"'
Autor:
Kelly M. Potter, Jason N. Kennedy, Chukwudi Onyemekwu, Niall T. Prendergast, Pratik P. Pandharipande, E Wesley Ely, Christopher Seymour, Timothy D. Girard
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104942- (2024)
Summary: Background: To understand delirium heterogeneity, prior work relied on psychomotor symptoms or risk factors to identify subtypes. Data-driven approaches have used machine learning to identify biologically plausible, treatment-responsive subt
Externí odkaz:
https://doaj.org/article/cc520dd1c1d545d68d1c1dc5a2e0c85e
Autor:
Catriona T. Prendergast, Robert A. Benson, Hannah E. Scales, Caio Santos Bonilha, John J. Cole, Iain McInnes, James M. Brewer, Paul Garside
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Mechanisms governing entry and exit of immune cells into and out of inflamed joints remain poorly understood. We sought herein to identify the key molecular pathways regulating such migration. Using murine models of inflammation in conjunction with m
Externí odkaz:
https://doaj.org/article/5d1175430835444c926fbbd904727585
Autor:
Daniel Paape, Catriona T. Prendergast, Helen P. Price, Johannes S. P. Doehl, Deborah F. Smith
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract Background Proving that specific genes are essential for the intracellular viability of Leishmania parasites within macrophages remains a challenge for the identification of suitable targets for drug development. This is especially evident i
Externí odkaz:
https://doaj.org/article/463f0595daaf427186f4594b3dbf6a5a
Autor:
Shaima Al Khabouri, Robert A. Benson, Catriona T. Prendergast, Joshua I. Gray, Thomas D. Otto, James M. Brewer, Paul Garside
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Effective tolerogenic intervention in Rheumatoid Arthritis (RA) will rely upon understanding the evolution of articular antigen specific CD4 T cell responses. TCR clonality of endogenous CD4 T cell infiltrates in early inflammatory arthritis was asse
Externí odkaz:
https://doaj.org/article/f24f091353d845b49a310b48bae536ce
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004911 (2016)
In a murine model of repeated exposure of the skin to infective Schistosoma mansoni cercariae, events leading to the priming of CD4 cells in the skin draining lymph nodes were examined. The dermal exudate cell (DEC) population recovered from repeated
Externí odkaz:
https://doaj.org/article/3d59119ecf844210b0c3cd3de0d02111
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004841 (2015)
The skin provides an important first line of defence and immunological barrier to invasive pathogens, but immune responses must also be regulated to maintain barrier function and ensure tolerance of skin surface commensal organisms. In schistosomiasi
Externí odkaz:
https://doaj.org/article/2402fa00dc86412bb47969fcc9c811df
Autor:
Rhoanne C McPherson, Joanne E Konkel, Catriona T Prendergast, John P Thomson, Raffaele Ottaviano, Melanie D Leech, Oliver Kay, Stephanie E J Zandee, Claire H Sweenie, David C Wraith, Richard R Meehan, Amanda J Drake, Stephen M Anderton
Publikováno v:
eLife, Vol 3 (2014)
Clinically effective antigen-based immunotherapy must silence antigen-experienced effector T cells (Teff) driving ongoing immune pathology. Using CD4+ autoimmune Teff cells, we demonstrate that peptide immunotherapy (PIT) is strictly dependent upon s
Externí odkaz:
https://doaj.org/article/75862575f3834eacaa2391d9b4e2cb34
Publikováno v:
Acta Horticulturae. :535-538
The Heat Pulse Velocity technique (HPV) is a method for determining sap flow velocity through plant stems and, subsequently, plant water use. The ‘T max ’ HPV method measures the time taken for a maximum temperature rise to be recorded by a singl
Publikováno v:
Agricultural and Forest Meteorology. 66:193-210
An eddy correlation system for carbon dioxide and latent heat flux measurement comprising a twin-channel, closed-path infra-red gas analyzer and sonic anemometer is described. Its performance was examined by comparing latent heat fluxes measured conc
Publikováno v:
Agricultural and Forest Meteorology. 57:253-264
Eddy correlation measurements of sensible heat and evaporation fluxes from a kiwifruit orchard confirm earlier, less comprehensive measurements that the spatially-averaged evaporation rate from well-watered and well-sheltered orchard blocks in the no