Zobrazeno 1 - 10
of 16
pro vyhledávání: '"P. T. Marth"'
Autor:
Xiaomeng Huang, Anthony D. Pomicter, Jonathan Ahmann, Yi Qiao, Opal S. Chen, Tracy I. George, Nataly Cruz-Rodriguez, Sameer Ahmad Guru, Gabor T. Marth, Michael W. Deininger
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/6d1a4f2a8ef544079d09fbe9f9e02a8c
Autor:
Xiaomeng Huang, Yi Qiao, Samuel W. Brady, Rachel E. Factor, Erinn Downs-Kelly, Andrew Farrell, Jasmine A. McQuerry, Gajendra Shrestha, David Jenkins, W. Evan Johnson, Adam L. Cohen, Andrea H. Bild, Gabor T. Marth
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Background Metastatic breast cancer is a deadly disease with a low 5-year survival rate. Tracking metastatic spread in living patients is difficult and thus poorly understood. Methods Via rapid autopsy, we have collected 30 tumor samples ove
Externí odkaz:
https://doaj.org/article/6f48789139544631a3eabb9929b6e5ba
Autor:
Thomas J. Nicholas, Michael J. Cormier, Xiaomeng Huang, Yi Qiao, Gabor T. Marth, Aaron R. Quinlan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background DNA sequencing has unveiled extensive tumor heterogeneity in several different cancer types, with many exhibiting diverse subclonal populations. Identifying and tracing mutations throughout the expansion and progression of a tumor
Externí odkaz:
https://doaj.org/article/e1da1938fbef4e359f6fe7d05b573c8c
Autor:
Vincent A. Primo, Yasaman Rezvani, Andrew Farrell, Connor Q. Murphy, Jingjing Lou, Amir Vajdi, Gabor T. Marth, Kourosh Zarringhalam, Marc-Jan Gubbels
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT Evolve and resequencing (E&R) was applied to lab adaptation of Toxoplasma gondii for over 1,500 generations with the goal of mapping host-independent in vitro virulence traits. Phenotypic assessments of steps across the lytic cycle revealed
Externí odkaz:
https://doaj.org/article/baa2835ddc1b4664a563da5e40bc4eb3
Autor:
Mark J. P. Chaisson, Ashley D. Sanders, Xuefang Zhao, Ankit Malhotra, David Porubsky, Tobias Rausch, Eugene J. Gardner, Oscar L. Rodriguez, Li Guo, Ryan L. Collins, Xian Fan, Jia Wen, Robert E. Handsaker, Susan Fairley, Zev N. Kronenberg, Xiangmeng Kong, Fereydoun Hormozdiari, Dillon Lee, Aaron M. Wenger, Alex R. Hastie, Danny Antaki, Thomas Anantharaman, Peter A. Audano, Harrison Brand, Stuart Cantsilieris, Han Cao, Eliza Cerveira, Chong Chen, Xintong Chen, Chen-Shan Chin, Zechen Chong, Nelson T. Chuang, Christine C. Lambert, Deanna M. Church, Laura Clarke, Andrew Farrell, Joey Flores, Timur Galeev, David U. Gorkin, Madhusudan Gujral, Victor Guryev, William Haynes Heaton, Jonas Korlach, Sushant Kumar, Jee Young Kwon, Ernest T. Lam, Jong Eun Lee, Joyce Lee, Wan-Ping Lee, Sau Peng Lee, Shantao Li, Patrick Marks, Karine Viaud-Martinez, Sascha Meiers, Katherine M. Munson, Fabio C. P. Navarro, Bradley J. Nelson, Conor Nodzak, Amina Noor, Sofia Kyriazopoulou-Panagiotopoulou, Andy W. C. Pang, Yunjiang Qiu, Gabriel Rosanio, Mallory Ryan, Adrian Stütz, Diana C. J. Spierings, Alistair Ward, AnneMarie E. Welch, Ming Xiao, Wei Xu, Chengsheng Zhang, Qihui Zhu, Xiangqun Zheng-Bradley, Ernesto Lowy, Sergei Yakneen, Steven McCarroll, Goo Jun, Li Ding, Chong Lek Koh, Bing Ren, Paul Flicek, Ken Chen, Mark B. Gerstein, Pui-Yan Kwok, Peter M. Lansdorp, Gabor T. Marth, Jonathan Sebat, Xinghua Shi, Ali Bashir, Kai Ye, Scott E. Devine, Michael E. Talkowski, Ryan E. Mills, Tobias Marschall, Jan O. Korbel, Evan E. Eichler, Charles Lee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Structural variants (SVs) in human genomes contribute diversity and diseases. Here, the authors use a multi-platform strategy to generate haplotype-resolved SVs for three human parent–child trios.
Externí odkaz:
https://doaj.org/article/1bf8e1b79b09479e9b177f1082c620e1
Autor:
David A Nix, Sabine Hellwig, Christopher Conley, Alun Thomas, Carrie L Fuertes, Cindy L Hamil, Preetida J Bhetariya, Ignacio Garrido-Laguna, Gabor T Marth, Mary P Bronner, Hunter R Underhill
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229063 (2020)
Challenges with distinguishing circulating tumor DNA (ctDNA) from next-generation sequencing (NGS) artifacts limits variant searches to established solid tumor mutations. Here we show early and random PCR errors are a principal source of NGS noise th
Externí odkaz:
https://doaj.org/article/5718b9aa273541e6820abd8340717128
Autor:
Alistair Ward, Mary A. Karren, Tonya Di Sera, Chase Miller, Matt Velinder, Yi Qiao, Francis M. Filloux, Betsy Ostrander, Russell Butterfield, Joshua L. Bonkowsky, Willard Dere, Gabor T. Marth
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 381-386 (2017)
IntroductionComputational analysis of genome or exome sequences may improve inherited disease diagnosis, but is costly and time-consuming.MethodsWe describe the use of iobio, a web-based tool suite for intuitive, real-time genome diagnostic analyses.
Externí odkaz:
https://doaj.org/article/0f0a690e74cd4c9ca40ed9325a12314f
Autor:
Sabine Hellwig, David A Nix, Keith M Gligorich, John M O'Shea, Alun Thomas, Carrie L Fuertes, Preetida J Bhetariya, Gabor T Marth, Mary P Bronner, Hunter R Underhill
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0197333 (2018)
Circulating tumor-derived cell-free DNA (ctDNA) enables non-invasive diagnosis, monitoring, and treatment susceptibility testing in human cancers. However, accurate detection of variant alleles, particularly during untargeted searches, remains a prin
Externí odkaz:
https://doaj.org/article/757b4bcee6f344cda97d7d9a78e756a2
Publikováno v:
Cancer Informatics, Vol 2015, Iss Suppl. 1, Pp 37-44 (2015)
Externí odkaz:
https://doaj.org/article/f1ccd4e8808d4444b78222c3b171f817
Publikováno v:
Cancer Informatics, Vol 2014, Iss Suppl. 4, Pp 45-52 (2014)
Externí odkaz:
https://doaj.org/article/490428729cce49b693caa54065871c96