Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P. T. Kaumaya"'
Publikováno v:
Biopolymers. 96:207-221
Mitochondria are the major source of reactive oxygen species. Both complex I and complex II mediate O2•− production in mitochondria and host reactive protein thiols. To explore the functions of the specific domains involved in the redox modificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fe683c9c94cc850b5b21236ae4dfd4
https://doi.org/10.1002/bip.21457
https://doi.org/10.1002/bip.21457
Autor:
Jingfeng Chen, Pravin P. T. Kaumaya, Saradhadevi Varadharaj, Jay L. Zweier, Yeong Renn Chen, Chwen Lih Chen, Sharad Rawale
Publikováno v:
Journal of Biological Chemistry. 283:27991-28003
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef5c50a2c50d9e4b9938a8148c96216
https://doi.org/10.1074/jbc.m802691200
https://doi.org/10.1074/jbc.m802691200
Publikováno v:
The Journal of Immunology. 160:5646-5652
In these studies, we determined whether there are receptors for the anaphylatoxin C5a (C5aR, CD88) on human mesangial cells (HMC). To prepare Abs to C5aR, we first synthesized an immunogenic peptide spanning residues 8–32 of the molecule, and this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac92c1f1134d3e5fe829943ac00fb4ec
https://doi.org/10.4049/jimmunol.160.11.5646
https://doi.org/10.4049/jimmunol.160.11.5646
Publikováno v:
Cancer research. 60(14)
Synthetic peptide vaccines targeting B-cell epitopes of the extracellular domain of the HER-2 oncoprotein were evaluated for their capacity to elicit HER-2-specific antibodies with antiproliferative activity. Several HER-2 B-cell epitopes were identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddaf60f522d341f57f743eb6cf524523
https://pubmed.ncbi.nlm.nih.gov/10919651
https://pubmed.ncbi.nlm.nih.gov/10919651
Publikováno v:
Oncoimmunology
Overexpression of HER-2 and VEGF plays a key role in the development and metastasis of several human cancers. Many FDA-approved therapies targeting both HER-2 (Trastuzumab, Herceptin) and VEGF (Bevacizumab, Avastin) are expensive, have unacceptable t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa419f96f9ae5acc88129d64f707a854
https://doi.org/10.4161/onci.23914
https://doi.org/10.4161/onci.23914
Publikováno v:
Leukemia. 9
Human T-lymphotropic virus type 1 (HTLV-I) is a retrovirus associated with adult T-cell leukemia/lymphoma, and the virus infection constitutes a growing public health problem. In a continuing effort to engineer conformationally dependent HTLV-I epito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0696790e4501fdb7778b1ddc03863fd0
https://pubmed.ncbi.nlm.nih.gov/7475306
https://pubmed.ncbi.nlm.nih.gov/7475306
Publikováno v:
Biomedical peptides, proteinsnucleic acids : structure, synthesisbiological activity. 1(3)
Activating mutations of the p21 ras proto-oncogene are involved in the development of many common malignancies. Because activating mutations are limited in number, occur within otherwise completely conserved regions, and can be expressed by premalign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0616a34111adbf02faee5501b8a5be11
https://pubmed.ncbi.nlm.nih.gov/9346851
https://pubmed.ncbi.nlm.nih.gov/9346851
Publikováno v:
Biomedical peptides, proteinsnucleic acids : structure, synthesisbiological activity. 1(3)
Human T-lymphotropic virus type 1 (HTLV-I) causes adult T-cell leukemia/lymphoma (ATLL) and has been associated with a variety of immunologically-mediated diseases. Recently, the immunodominant epitopes of HTLV-I have begun to be defined through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91dd02e6fb43d56bcf894a51b30c7e5b
https://pubmed.ncbi.nlm.nih.gov/9346842
https://pubmed.ncbi.nlm.nih.gov/9346842
Publikováno v:
The Journal of biological chemistry. 268(34)
The use of peptides has attracted much interest in the development of synthetic vaccines. Although our current understanding of peptide antigens as immunogens has been greatly advanced recently, there still remain many obstacles. The B cell response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::630be862272e0ebef7b6b69b1f7fbf55
https://pubmed.ncbi.nlm.nih.gov/8244959
https://pubmed.ncbi.nlm.nih.gov/8244959
Publikováno v:
The Journal of biological chemistry. 267(9)
Antibodies elicited by immunization with short peptides containing antigenic determinants have been shown, in general, to bind with greatly reduced affinity to the corresponding region in the native proteins. Thus, contiguous linear peptides have not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::350489fc6c3e1df17173d8f1cb09963a
https://pubmed.ncbi.nlm.nih.gov/1372905
https://pubmed.ncbi.nlm.nih.gov/1372905