Výsledky vyhledávání - "P. T. Daley-Yates"

Pharmacokinetics, toxicokinetics, distribution, metabolism and excretion of linezolid in mouse, rat and dog

Autor: J P Sams, Kenneth L. Feenstra, K. Chiba, S Yamazaki, M R Schuette, N. Ozawa, S Koike, J. G. Slatter, P T Daley-Yates, L A Adams, G. W. Peng, E C Bush

Publikováno v: Xenobiotica. 32:907-924

1. Linezolid (ZYVOX), the first of a new class of antibiotics, the oxazolidinones, is approved for treatment of Gram-positive bacterial infections. 2. The aim was to determine the absorption, distribution, metabolism and excretion (ADME) of linezolid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f8fa95fc172b89db3bc048187e732c
https://doi.org/10.1080/00498250210158249

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From hydrofluoroalkane pressurized metered dose inhalers (pMDIs) and comparability with chlorofluorocarbon pMDIs

Autor: R, Kunka, S, Andrews, M, Pimazzoni, S, Callejas, L, Ziviani, L, Squassante, P T, Daley-Yates

Publikováno v: Respiratory medicine. 94

Fluticasone propionate pressurized metered dose inhalers (pMDIs) containing the hydrofluoroalkane (HFA) propellant, HFA 134a, are being developed to replace existing chlorofluorocarbon (CFC) pMDIs. This is part of the ongoing worldwide project to lim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2e806f323855aee4ce8cd2af8fa785e
https://pubmed.ncbi.nlm.nih.gov/11217914

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Pharmacokinetic and pharmacodynamic assessment of bioavailability for two prodrugs of methylprednisolone

Autor: C. D. Brooks, A. J. Gregory, P. T. Daley-Yates

Publikováno v: British journal of clinical pharmacology. 43(6)

Aims The aim of this study was to establish whether pharmacokinetic differences between two pro-drugs of methylprednisolone (MP) are likely to be of clinical significance. Methods This study was a single-blind, randomized, crossover design comparing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1348a696c78516c56416cad60e98a7d9
https://pubmed.ncbi.nlm.nih.gov/9205819

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A comparative population pharmacokinetic analysis for methylprednisolone following multiple dosing of two prodrugs in patients with acute asthma

Autor: S. A. Wood, P. T. Daley‐Yates, T. J Parker

Aims To conduct a randomized, parallel group comparison of the population pharmacokinetics of the two methylprednisolone (MP) prodrugs Promedrol (MP suleptanate) and Solu-Medrol (MP succinate) in patients hospitalized with acute asthma. Methods Ninet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43495f279650eb4492649fdb96f8046
https://europepmc.org/articles/PMC2042787/

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Clearance and tissue uptake following 4-hour and 24-hour infusions of pamidronate in rats

Autor: M, Pongchaidecha, P T, Daley-Yates

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 21(1)

Bisphosphonates are clinically useful for the treatment of bone disorders; however, there is some controversy concerning the extent to which the design of the dosage regimen influences the efficacy of these drugs. The effect of different rates of inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca75344e9adb890bb9c9cbc48791c43d
https://pubmed.ncbi.nlm.nih.gov/8095201

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Short papers in pharmaceutical analysis

Autor: Z. Pawlak, D. Kay, B. J. Clark, C. R. Hoggarth, L. A. Gifford, P. T. Daley-Yates, Donald A. Clark, Gary Nichols, P. J. Weir, D. S. Ireland, David Graham, A. C. Metcalf, N. A. Undre, A. Beerahee, A. R. Thawley, G. W. Ley, A. F. Fell, B. Kaye

Publikováno v: Analytical Proceedings. 27:16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::255ac703e38cd5f13d62a7d4da372220
https://doi.org/10.1039/ap9902700016

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