Zobrazeno 1 - 10
of 341
pro vyhledávání: '"P. Spiropoulou"'
Autor:
Elif Karaaslan, Teresa E. Sorvillo, Florine E. M. Scholte, Troy Justin O’Neal, Stephen R. Welch, Katherine A. Davies, JoAnn D. Coleman-McCray, Jessica R. Harmon, Jana M. Ritter, Scott D. Pegan, Joel M. Montgomery, Jessica R. Spengler, Christina F. Spiropoulou, Éric Bergeron
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Immunizing mice with Crimean-Congo hemorrhagic fever virus (CCHFV) nucleoprotein (NP), glycoprotein precursor (GPC), or with the GP38 domain of GPC, can be protective when the proteins are delivered with viral vectors or as a DNA or RNA vacc
Externí odkaz:
https://doaj.org/article/c721bc91b40f410a9bf386bc947427cd
Autor:
Teresa E. Sorvillo, Elif Karaaslan, Florine E. M. Scholte, Stephen R. Welch, JoAnn D. Coleman-McCray, Sarah C. Genzer, Jana M. Ritter, Heather M. Hayes, Shilpi Jain, Scott D. Pegan, Éric Bergeron, Joel M. Montgomery, Christina F. Spiropoulou, Jessica R. Spengler
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Crimean-Congo hemorrhagic fever virus (CCHFV) can cause severe human disease and is considered a WHO priority pathogen due to the lack of efficacious vaccines and antivirals. A CCHF virus replicon particle (VRP) has previously shown protecti
Externí odkaz:
https://doaj.org/article/b8ba679dc1ff413493a3bbf4a114e16c
Autor:
Éric Bergeron, Cheng-Feng Chiang, Michael K. Lo, Elif Karaaslan, Syed Moinuddin Satter, Mohammed Ziaur Rahman, Mohammad Enayet Hossain, Wasik Rahman Aquib, Dewan Imtiaz Rahman, Subyeta Binte Sarwar, Joel M. Montgomery, John D. Klena, Christina F. Spiropoulou
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Nipah virus (NiV) is an emerging zoonotic RNA virus that can cause fatal respiratory and neurological diseases in animals and humans. Accurate NiV diagnostics and surveillance tools are crucial for the identification of acute and resolved infections
Externí odkaz:
https://doaj.org/article/60ccc5f5b3bb498ca72e4ac3a8002ad3
Autor:
Florine E.M. Scholte, Jessica R. Spengler, Stephen R. Welch, Jessica R. Harmon, JoAnn D. Coleman-McCray, Katherine A. Davies, Scott D. Pegan, Joel M. Montgomery, Christina F. Spiropoulou, Éric Bergeron
Publikováno v:
Virus Research, Vol 345, Iss , Pp 199398- (2024)
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne nairovirus with a wide geographic spread that can cause severe and lethal disease. No specific medical countermeasures are approved to combat this illness. The CCHFV L protein contains an
Externí odkaz:
https://doaj.org/article/11d89857f10b4fc099fb394c35126e4e
Autor:
Maya Michon, Andreas Müller-Schiffmann, Anuradha F. Lingappa, Shao Feng Yu, Li Du, Fred Deiter, Sean Broce, Suguna Mallesh, Jackelyn Crabtree, Usha F. Lingappa, Amanda Macieik, Lisa Müller, Philipp Niklas Ostermann, Marcel Andrée, Ortwin Adams, Heiner Schaal, Robert J. Hogan, Ralph A. Tripp, Umesh Appaiah, Sanjeev K. Anand, Thomas W. Campi, Michael J. Ford, Jonathan C. Reed, Jim Lin, Olayemi Akintunde, Kiel Copeland, Christine Nichols, Emma Petrouski, Ana R. Moreira, I-ting Jiang, Nicholas DeYarman, Ian Brown, Sharon Lau, Ilana Segal, Danielle Goldsmith, Shi Hong, Vinod Asundi, Erica M. Briggs, Ngwe Sin Phyo, Markus Froehlich, Bruce Onisko, Kent Matlack, Debendranath Dey, Jaisri R. Lingappa, Dharma M. Prasad, Anatoliy Kitaygorodskyy, Dennis Solas, Homer Boushey, John Greenland, Satish Pillai, Michael K. Lo, Joel M. Montgomery, Christina F. Spiropoulou, Carsten Korth, Suganya Selvarajah, Kumar Paulvannan, Vishwanath R. Lingappa
Publikováno v:
Open Biology, Vol 14, Iss 6 (2024)
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431, a representative compound fr
Externí odkaz:
https://doaj.org/article/ab895c6ab92c405ab16479c74bcf64ea
Autor:
Katherine A. Davies, Stephen R. Welch, Teresa E. Sorvillo, JoAnn D. Coleman-McCray, María Laura Martin, Julia M. Brignone, Joel M. Montgomery, Christina F. Spiropoulou, Jessica R. Spengler
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Reverse-transcription quantitative polymerase chain reaction assays are frequently used to evaluate gene expression in animal model studies. Data analyses depend on normalization using a suitable reference gene (RG) to minimize effects of va
Externí odkaz:
https://doaj.org/article/a5d3c87bfb844e439ea727a71d54082b
Autor:
Emily S. Medina-Magües, Jaime Lopera-Madrid, Michael K. Lo, Christina F. Spiropoulou, Joel M. Montgomery, Lex G. Medina-Magües, Cristhian Salas-Quinchucua, Angela P. Jiménez-Mora, Jorge E. Osorio
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Nipah virus (NiV), an emerging zoonotic pathogen in Southeast Asia, is transmitted from Pteropus species of fruit bats to a wide range of species, including humans, pigs, horses, dogs, and cats. NiV has killed millions of animals and caused
Externí odkaz:
https://doaj.org/article/6e9710fa46a148618b915487e83aa255
Autor:
Markus H. Kainulainen, Jessica R. Harmon, Amy N. Whitesell, Éric Bergeron, Elif Karaaslan, Caitlin M. Cossaboom, Jason H. Malenfant, Aaron Kofman, Joel M. Montgomery, Mary J. Choi, César G. Albariño, Christina F. Spiropoulou
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Ebola disease outbreaks are major public health events because of human-to-human transmission and high mortality. These outbreaks are most often caused by Ebola virus, but at least three related viruses can also cause the disease. In 2022, Sudan viru
Externí odkaz:
https://doaj.org/article/7074e15bc8074ab7990517a437b78132
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Akademický článek
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