Zobrazeno 1 - 10
of 663
pro vyhledávání: '"P. Simani"'
Autor:
Dorcas Maruapula, Doreen Ditshwanelo, Marea N. Pema, Ontlametse T. Bareng, Wonderful T. Choga, Natasha O. Moraka, Patrick T. Mokgethi, Kaelo K. Seatla, Catherine K. Koofhethile, Boitumelo J. Zuze, Tendani Gaolathe, Molly Pretorius-Holme, Kebaneilwe Lebani, Joseph Makhema, Vlad Novitsky, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundWe evaluated the prevalence of archived proviral drug resistance mutations (DRMs) associated with resistance to integrase strand transfer inhibitors (INSTIs) shortly before Botswana transitioned in 2016 to using dolutegravir (DTG)-based ant
Externí odkaz:
https://doaj.org/article/38caff23dfd94972b28750adba2eaf3b
Autor:
Arman Ahmadzade, Leila Simani, Mehrdad Roozbeh, Farane Farsad, Mehdi Sheibani, Omid Negaresh, Mohammad Mehdi Emam, Alireza Rajaei, Muhanna Kazempour, Mahtab Ramezani, samad nazarpoor
Publikováno v:
Caspian Journal of Internal Medicine, Vol 15, Iss 1, Pp 58-65 (2024)
Background: Diagnosis of neuropsychiatric systemic lupus erythematosus (NPSLE) is challenging due to nonspecific biomarkers. High serum levels of neurofilament protein light subunit (NFL), high mobility group box 1 (HMGB1), Matrix metalloproteinase-9
Externí odkaz:
https://doaj.org/article/f326f86427bf405ea6f04cb9e245f9f2
Autor:
Wonderful T. Choga, Gobuiwang Khilly Kurusa (Gasenna), James Emmanuel San, Tidimalo Ookame, Irene Gobe, Mohammed Chand, Badisa Phafane, Kedumetse Seru, Patience Matshosi, Boitumelo Zuze, Nokuthula Ndlovu, Teko Matsuru, Dorcas Maruapula, Ontlametse T. Bareng, Kutlo Macheke, Lesego Kuate-Lere, Labapotswe Tlale, Onalethata Lesetedi, Modiri Tau, Mpaphi B. Mbulawa, Pamela Smith-Lawrence, Mogomotsi Matshaba, Roger Shapiro, Joseph Makhema, Darren P. Martin, Tulio de Oliveira, Richard J. Lessells, Shahin Lockman, Simani Gaseitsiwe, Sikhulile Moyo
Publikováno v:
International Journal of Infectious Diseases, Vol 138, Iss , Pp 91-96 (2024)
We investigated intra-host genetic evolution using two SARS-CoV-2 isolates from a fully vaccinated (primary schedule x2 doses of AstraZeneca plus a booster of Pfizer), >70-year-old woman with a history of lymphoma and hypertension who presented a SAR
Externí odkaz:
https://doaj.org/article/a4563b67ede2463ca061c016f76e974e
Publikováno v:
Epilepsia Open, Vol 8, Iss 4, Pp 1425-1431 (2023)
Abstract Objective We investigated the association between the glucocorticoid receptor (GR) gene, also known as the nuclear receptor subfamily 3, group C, member 1 (NR3C1), rs41423247 polymorphism, and functional seizures (psychogenic nonepileptic se
Externí odkaz:
https://doaj.org/article/e05c0ce5fc0442b6830660f522b2b602
Autor:
Kabo Baruti, Wonderful T. Choga, Patience C. Motshosi, Bonolo B. Phinius, Basetsana Phakedi, Lynnette N. Bhebhe, Gorata G. A. Mpebe, Chanana D. Tsayang, Tsholofelo Ratsoma, Tendani Gaolathe, Mosepele Mosepele, Joseph Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Mosimanegape Jongman, Motswedi Anderson, Simani Gaseitsiwe
Publikováno v:
Viruses, Vol 16, Iss 10, p 1568 (2024)
Hepatitis delta virus (HDV) co-infections more often result in severe hepatitis compared to hepatitis B virus (HBV) infections alone. Despite a high HDV prevalence (7.1%), information regarding circulating HDV clades is very limited in Botswana. We e
Externí odkaz:
https://doaj.org/article/2d6198167f544ac78b046379bd6afd2a
Autor:
Motswedi Anderson, Bonolo B. Phinius, Basetsana K. Phakedi, Mbatshi Mudanga, Lynnette N. Bhebhe, Girlie N. Tlhabano, Patience Motshosi, Tsholofelo Ratsoma, Kabo Baruti, Gorata Mpebe, Wonderful T. Choga, Richard Marlink, Dieter Glebe, Jason T. Blackard, Sikhulile Moyo, Anna Kramvis, Simani Gaseitsiwe
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
AimThis study aimed to determine the kinetics of occult hepatitis B virus infections (OBI) among people with HIV (PWH).MethodsThe study used archived plasma samples from longitudinal HIV natural history studies. We identified new OBI cases and assess
Externí odkaz:
https://doaj.org/article/a1fb6e1bfe774ca3bcb77efb42001557
Autor:
Kabo Baruti, Bonolo B. Phinius, Basetsana Phakedi, Gorata Mpebe, Wonderful Choga, Lynnette Bhebhe, Graceful Mulenga, Natasha O. Moraka, Tsholofelo Ratsoma, Molly Pretorius-Holme, Joseph Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Mosimanegape Jongman, Motswedi Anderson, Simani Gaseitsiwe
Publikováno v:
Journal of Infection and Public Health, Vol 16, Iss 11, Pp 1736-1741 (2023)
Background: Approximately 15–20 million people worldwide are infected with hepatitis delta virus (HDV), which is approximately 5 % of people with chronic hepatitis B virus (HBV). Sub-Saharan Africa has high HDV prevalence, leading to worse clinical
Externí odkaz:
https://doaj.org/article/dd66fdf5db2c49a28d573a6c8fee0b9e
Autor:
Natasha O. Moraka, Wonderful T. Choga, Marea N. Pema, Moses Kudzai Chawawa, Irene Gobe, Margaret Mokomane, Ontlametse T. Bareng, Lynette Bhebhe, Nametso Kelentse, Graceful Mulenga, Molly Pretorius Holme, Terence Mohammed, Catherine K. Koofhethile, Joseph M. Makhema, Roger Shapiro, Shahin Lockman, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract We used HIV-1C sequences to predict (in silico) resistance to 33 known broadly neutralizing antibodies (bnAbs) and evaluate the different HIV-1 Env characteristics that may affect virus neutralization. We analyzed proviral sequences from adu
Externí odkaz:
https://doaj.org/article/34cd02c202c244d98df4161bb39f3c8a
Publikováno v:
Algorithms, Vol 17, Iss 7, p 306 (2024)
This article presents an in-depth analysis of three advanced strategies to tune fractional PID (FOPID) controllers for a nonlinear system of interconnected tanks, simulated using MATLAB. The study focuses on evaluating the performance characteristics
Externí odkaz:
https://doaj.org/article/b42856d9fb7840d69da96939a16dd5a0
Autor:
Bonolo B. Phinius, Wonderful T. Choga, Motswedi Anderson, Margaret Mokomane, Irene Gobe, Tsholofelo Ratsoma, Basetsana Phakedi, Gorata Mpebe, Lynnette Bhebhe, Tendani Gaolathe, Mosepele Mosepele, Joseph Makhema, Roger Shapiro, Shahin Lockman, Rosemary Musonda, Sikhulile Moyo, Simani Gaseitsiwe
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1561 (2024)
(1) Background: Hepatitis B virus (HBV) sequencing data are important for monitoring HBV evolution. We aimed to molecularly characterize HBV sequences from participants with HBV surface antigen-positive (HBsAg+) serology and occult hepatitis B infect
Externí odkaz:
https://doaj.org/article/6829cfe2e45447ae99c2e3fcd79459a4