Zobrazeno 1 - 10
of 375
pro vyhledávání: '"P. Sehl"'
Autor:
Annika Graaf-Rau, Kathrin Schmies, Angele Breithaupt, Kevin Ciminski, Gert Zimmer, Artur Summerfield, Julia Sehl-Ewert, Kathrin Lillie-Jaschniski, Carina Helmer, Wiebke Bielenberg, Elisabeth grosse Beilage, Martin Schwemmle, Martin Beer, Timm Harder
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Swine influenza A viruses (swIAV) cause an economically important respiratory disease in modern pig production. Continuous virus transmission and antigenic drift are difficult to control in enzootically infected pig herds. Here, antibody-pos
Externí odkaz:
https://doaj.org/article/50b2b0dc3dd54ecf9cce3022d82807df
Autor:
Nico Joel Halwe, Lea Hamberger, Julia Sehl-Ewert, Christin Mache, Jacob Schön, Lorenz Ulrich, Sten Calvelage, Mario Tönnies, Jonas Fuchs, Pooja Bandawane, Madhumathi Loganathan, Anass Abbad, Juan Manuel Carreño, Maria C. Bermúdez-González, Viviana Simon, Ahmed Kandeil, Rabeh El-Shesheny, Mohamed A. Ali, Ghazi Kayali, Matthias Budt, Stefan Hippenstiel, Andreas C. Hocke, Florian Krammer, Thorsten Wolff, Martin Schwemmle, Kevin Ciminski, Donata Hoffmann, Martin Beer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Influenza A viruses (IAVs) of subtype H9N2 have reached an endemic stage in poultry farms in the Middle East and Asia. As a result, human infections with avian H9N2 viruses have been increasingly reported. In 2017, an H9N2 virus was isolated
Externí odkaz:
https://doaj.org/article/27c9b3ce2fd746359b0b64d22dcabd10
Autor:
Benedikt Litz, Julia Sehl-Ewert, Angele Breithaupt, Anja Landmesser, Florian Pfaff, Aurore Romey, Sandra Blaise-Boisseau, Martin Beer, Michael Eschbaumer
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTThe foot-and-mouth disease virus (FMDV) Leader proteinase Lpro inhibits host mRNA translation and blocks the interferon response which promotes viral survival. Lpro is not required for viral replication in vitro but serotype A FMDV lacking Lp
Externí odkaz:
https://doaj.org/article/d0eeabbaab914660bf5af81fb317a4d2
Autor:
Joshua Zhang, Mary E. Sehl, Roger Shih, Elizabeth Crabb Breen, Fengxue Li, Ake T. Lu, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Steve Horvath, Beth D. Jamieson
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Introduction: Highly active antiretroviral therapy (HAART) helps improve some measures of accelerated epigenetic aging in persons living with HIV (PLWH), but its overall impact on the epigenome is not fully understood.Methods: In this study, we analy
Externí odkaz:
https://doaj.org/article/b3905060df8f42c5b15b836f9f6b4669
Autor:
Mary E. Sehl, Elizabeth Crabb Breen, Roger Shih, Fengxue Li, Joshua Zhang, Peter Langfelder, Steve Horvath, Jay H. Bream, Priya Duggal, Jeremy Martinson, Steven M. Wolinsky, Otoniel Martinez-Maza, Christina M. Ramirez, Beth D. Jamieson
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
IntroductionPersons living with HIV (PLWH) experience the early onset of age-related illnesses, even in the setting of successful human immunodeficiency virus (HIV) suppression with highly active antiretroviral therapy (HAART). HIV infection is assoc
Externí odkaz:
https://doaj.org/article/b9807aa06bea4118a72dfc77fba1c39e
Multitype branching processes are ideal for studying the population dynamics of stem cell populations undergoing mutation accumulation over the years following transplant. In such stochastic models, several quantities are of clinical interest as inse
Externí odkaz:
http://arxiv.org/abs/2111.08183
Autor:
Emmelie Eckhardt, Jan Schinköthe, Marcel Gischke, Julia Sehl-Ewert, Björn Corleis, Anca Dorhoi, Jens Teifke, Dirk Albrecht, Annemieke Geluk, Martine Gilleron, Max Bastian
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The concept of donor-unrestricted T cells (DURTs) comprises a heterogeneity of lymphoid cells that respond to an abundance of unconventional epitopes in a non-MHC-restricted manner. Vaccinologists strive to harness this so far underexplored
Externí odkaz:
https://doaj.org/article/6b0b03d569bd4a84846e547c1e6ecf40
Autor:
Annika Graaf, Ronja Piesche, Julia Sehl-Ewert, Christian Grund, Anne Pohlmann, Martin Beer, Timm Harder
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 7, Pp 1492-1495 (2023)
We found that nasal and alimentary experimental exposure of pigs to highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b was associated with marginal viral replication, without inducing any clinical manifestation or pathological changes. Only
Externí odkaz:
https://doaj.org/article/cac87d432d0e4175b9487c636edbeafc
Autor:
Conrad M. Freuling, Andreas Hlinak, Christoph Schulze, Julia Sehl-Ewert, Patrick Wysocki, Claudia A. Szentiks, Klaus Schmitt, Peter Wohlsein, Gesa Kluth, Ilka Reinhardt, Thomas C. Mettenleiter, Thomas Müller
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background The high susceptibility of carnivores to Suid Alphaherpesvirus 1 [SuAHV1, synonymous pseudorabies virus (PrV)], renders them inadvertent sentinels for the possible occurrence of Aujeszky’s disease (AD) in domestic and wild swine
Externí odkaz:
https://doaj.org/article/19fd9a4855f149d5b75648f37f576dd9
Autor:
Paul Deutschmann, Jan-Hendrik Forth, Julia Sehl-Ewert, Tessa Carrau, Elisenda Viaplana, Jose Carlos Mancera, Alicia Urniza, Martin Beer, Sandra Blome
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract African swine fever (ASF) has gained panzootic dimensions and commercial vaccines are still unavailable. Recently, a series of live attenuated vaccines has raised hope for an efficacious and safe vaccine, among them “ASFV-G-∆MGF”. We t
Externí odkaz:
https://doaj.org/article/5af739c0ee204f5b8a143f521657c317