UV-induced reactive oxygen species and transcriptional control of 3-deoxyanthocyanidin biosynthesis in black sorghum pericarp

Autor: Brooklyn Schumaker, Lauren Mortensen, Robert R. Klein, Sabyasachi Mandal, Linda Dykes, Nicholas Gladman, William L. Rooney, Byron Burson, Patricia E. Klein

Publikováno v: Frontiers in Plant Science, Vol 15 (2024)

Black pericarp sorghum has notable value due to the biosynthesis of 3-deoxyanthocyanidins (3-DOAs), a rare class of bioactive polyphenols valued as antioxidant food additives and as bioactive compounds with cytotoxicity to human cancer cells. A metab

Externí odkaz: https://doaj.org/article/702471dedce145aeb297922270378a5b

Perspectives from cystinosis: access to healthcare may be a confounding factor for variant classification

Autor: Chen-Han Wilfred Wu, Alicja Tomaszewski, Louisa Stark, Fernando Scaglia, Ewa Elenberg, Fredrick R. Schumaker

Publikováno v: Frontiers in Genetics, Vol 15 (2024)

Genetic variability persists across diverse populations, and it may impact the characterization of heritable diseases in different ancestral groups. Cystinosis is a metabolic disease caused by pathogenic variants in the CTNS gene causing the cellular

Externí odkaz: https://doaj.org/article/8fae72ba3cf744279b4ad06a791a86ad

Identification of CT-based non-invasive radiomic biomarkers for overall survival prediction in oral cavity squamous cell carcinoma

Autor: Xiao Ling, Gregory S. Alexander, Jason Molitoris, Jinhyuk Choi, Lisa Schumaker, Ranee Mehra, Daria A. Gaykalova, Lei Ren

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)

Abstract This study addresses the limited non-invasive tools for Oral Cavity Squamous Cell Carcinoma (OSCC) survival prediction by identifying Computed Tomography (CT)-based biomarkers to improve prognosis prediction. A retrospective analysis was con

Externí odkaz: https://doaj.org/article/9149484bdebc4f12be14cde083b98795

The SNO+ Experiment

Autor: Collaboration, SNO, Albanese, V., Alves, R., Anderson, M. R., Andringa, S., Anselmo, L., Arushanova, E., Asahi, S., Askins, M., Auty, D. J., Back, A. R., Back, S., Barão, F., Barnard, Z., Barr, A., Barros, N., Bartlett, D., Bayes, R., Beaudoin, C., Beier, E. W., Berardi, G., Bialek, A., Biller, S. D., Blucher, E., Bonventre, R., Boulay, M., Braid, D., Caden, E., Callaghan, E. J., Caravaca, J., Carvalho, J., Cavalli, L., Chauhan, D., Chen, M., Chkvorets, O., Clark, K. J., Cleveland, B., Connors, C., Cookman, D., Coulter, I. T., Cox, M. A., Cressy, D., Dai, X., Darrach, C., Davis-Purcell, B., Deluce, C., Depatie, M. M., Descamps, F., Di Lodovico, F., Dittmer, J., Doxtator, A., Duhaime, N., Duncan, F., Dunger, J., Earle, A. D., Fabris, D., Falk, E., Farrugia, A., Fatemighomi, N., Felber, C., Fischer, V., Fletcher, E., Ford, R., Frankiewicz, K., Gagnon, N., Gaur, A., Gauthier, J., Gibson-Foster, A., Gilje, K., González-Reina, O. I., Gooding, D., Gorel, P., Graham, K., Grant, C., Grove, J., Grullon, S., Guillian, E., Hall, S., Hallin, A. L., Hallman, D., Hans, S., Hartnell, J., Harvey, P., Hedayatipour, M., Heintzelman, W. J., Heise, J., Helmer, R. L., Hodak, B., Hodak, M., Hood, M., Horne, D., Hreljac, B., Hu, J., Hussain, S. M. A., Iida, T., Inácio, A. S., Jackson, C. M., Jelley, N. A., Jillings, C. J., Jones, C., Jones, P. G., Kamdin, K., Kaptanoglu, T., Kaspar, J., Keeter, K., Kefelian, C., Khaghani, P., Kippenbrock, L., Klein, J. R., Knapik, R., Kofron, J., Kormos, L. L., Korte, S., Krar, B., Kraus, C., Krauss, C. B., Kroupová, T., Labe, K., Lafleur, F., Lam, I., Lan, C., Land, B. J., Lane, R., Langrock, S., Larochelle, P., Larose, S., LaTorre, A., Lawson, I., Lebanowski, L., Lefeuvre, G. M., Leming, E. J., Li, A., Li, O., Lidgard, J., Liggins, B., Liimatainen, P., Lin, Y. H., Liu, X., Liu, Y., Lozza, V., Luo, M., Maguire, S., Maio, A., Majumdar, K., Manecki, S., Maneira, J., Martin, R. D., Marzec, E., Mastbaum, A., Mathewson, A., McCauley, N., McDonald, A. B., McFarlane, K., Mekarski, P., Meyer, M., Miller, C., Mills, C., Mlejnek, M., Mony, E., Morissette, B., Morton-Blake, I., Mottram, M. J., Nae, S., Nirkko, M., Nolan, L. J., Novikov, V. M., O'Keeffe, H. M., O'Sullivan, E., Gann, G. D. Orebi, Parnell, M. J., Paton, J., Peeters, S. J. M., Pershing, T., Petriw, Z., Petzoldt, J., Pickard, L., Pracsovics, D., Prior, G., Prouty, J. C., Quirk, S., Read, S., Reichold, A., Riccetto, S., Richardson, R., Rigan, M., Ritchie, I., Robertson, A., Robertson, B. C., Rose, J., Rosero, R., Rost, P. M., Rumleskie, J., Schumaker, M. A., Schwendener, M. H., Scislowski, D., Secrest, J., Seddighin, M., Segui, L., Seibert, S., Semenec, I., Shaker, F., Shantz, T., Sharma, M. K., Shokair, T. M., Sibley, L., Sinclair, J. R., Singh, K., Skensved, P., Smiley, M., Sonley, T., Sörensen, A., St-Amant, M., Stainforth, R., Stankiewicz, S., Strait, M., Stringer, M. I., Stripay, A., Svoboda, R., Tacchino, S., Tam, B., Tanguay, C., Tatar, J., Tian, L., Tolich, N., Tseng, J., Tseung, H. W. C., Turner, E., Van Berg, R., Vázquez-Jáuregui, E., Veinot, J. G. C., Virtue, C. J., von Krosigk, B., Walker, J. M. G., Walker, M., Wallig, J., Walton, S. C., Wang, J., Ward, M., Wasalski, O., Waterfield, J., Weigand, J. J., White, R. F., Wilson, J. R., Winchester, T. J., Woosaree, P., Wright, A., Yanez, J. P., Yeh, M., Zhang, T., Zhang, Y., Zhao, T., Zuber, K., Zummo, A.

Publikováno v: The SNO+ collaboration, 2021 JINST 16 P08059

The SNO+ experiment is located 2 km underground at SNOLAB in Sudbury, Canada. A low background search for neutrinoless double beta ($0\nu\beta\beta$) decay will be conducted using 780 tonnes of liquid scintillator loaded with 3.9 tonnes of natural te

Externí odkaz: http://arxiv.org/abs/2104.11687

A case of bacteremia and pneumonia caused by Streptococcus equi subspecies equi infection in a 70-year-old female following horse exposure in rural Wyoming

Autor: Tristan Bohlman, Heith Waddell, Brant Schumaker

Publikováno v: Annals of Clinical Microbiology and Antimicrobials, Vol 22, Iss 1, Pp 1-5 (2023)

Abstract Background The occurrence of zoonotic infections following an animal exposure continues to be an important consideration for all patients, especially those within agricultural communities. Streptococcus equi subspecies equi (S. equi subsp. e

Externí odkaz: https://doaj.org/article/bf1627d355da4b3187720b6e4ad67f9b