Zobrazeno 1 - 10
of 72
pro vyhledávání: '"P. Sammarco Rosa"'
Autor:
Tiago Araujo Gomes, Tatiana Pereira da Silva, Edson Machado, Sidra Ezidio Gonçalves Vasconcelos, Bruno Siqueira Mietto, Daniela Ferreira de Faria Bertoluci, Patricia Sammarco Rosa, Roberta Olmo Pinheiro, Philip Noel Suffys, Letícia Miranda Santos Lery, Flavio Alves Lara
Publikováno v:
Pathogens, Vol 13, Iss 11, p 986 (2024)
Throughout Mycobacterium leprae’s (M. leprae) evolutionary trajectory, nearly half of its genome was converted into pseudogenes. Despite this drastic reduction in genetic content, the genome sequence identity among M. leprae isolates worldwide is r
Externí odkaz:
https://doaj.org/article/fc976f82b1ce4c03bdc105b60aa1e32e
Autor:
Plinio Marcos Freire dos Santos, Chyntia Carolina Díaz Acosta, Thabatta Leal Silveira Andrezo Rosa, Michelle Harumi Ishiba, André Alves Dias, Antonio Marcos Rodrigues Pereira, Luísa Domingos Gutierres, Melissa Pontes Pereira, Matheus da Silva Rocha, Patrícia Sammarco Rosa, Daniele F. F. Bertoluci, José Roberto Meyer-Fernandes, Fabricio da Mota Ramalho Costa, Maria Angela M. Marques, John T. Belisle, Roberta Olmo Pinheiro, Luciana Silva Rodrigues, Maria Cristina Vidal Pessolani, Marcia Berrêdo-Pinho
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundLeprosy is a chronic infectious disease caused by Mycobacterium leprae, which can lead to a disabling neurodegenerative condition. M. leprae preferentially infects skin macrophages and Schwann cells–glial cells of the peripheral nervous s
Externí odkaz:
https://doaj.org/article/f7ff13b38ef44228826448b683d0162b
Autor:
Adriana Sierra Assencio Almeida Barbosa, Thayna Sosolote Lima, Beatriz Gomes Carreira Sartori, Suzana Madeira Diório, Sônia Maria Usó Ruiz Silva, Vania Nieto Brito-de-Souza, Maria Renata Sales Nogueira, Patrícia Sammarco Rosa, Sílvia Cristina Barboza Pedrini, Fátima Regina Vilani-Moreno
Publikováno v:
Hansenologia Internationalis, Vol 49 (2024)
Introdução: a hanseníase é uma doença in fecciosa crônica causada pelo Mycobacterium leprae (M. leprae), um parasita intracelular obrigatório. Assim, a resistência do hospedeiro a esse patógeno depende da imunidade celular. O uso de modelos
Externí odkaz:
https://doaj.org/article/0fbe063ceb9044ad8830594164233ad1
Autor:
Natália Aparecida de Paula, Marcel Nani Leite, Daniele Ferreira de Faria Bertoluci, Cleverson Teixeira Soares, Patrícia Sammarco Rosa, Marco Andrey Cipriani Frade
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 9, Iss 6, p 135 (2024)
The in vitro cultivation of M. leprae has not been possible since it was described as causing leprosy, and the limitation of animal models for clinical aspects makes studies on leprosy and bacteria–human host interaction a challenge. Our aim was to
Externí odkaz:
https://doaj.org/article/43b866f4c75c4e1096a3c942aa4710e7
Autor:
Rafael Saraiva de Andrade Rodrigues, Eduardo Ferreira José Heise, Luis Felipe Hartmann, Guilherme Eduardo Rocha, Marcia Olandoski, Mariane Martins de Araújo Stefani, Ana Carla Pereira Latini, Cleverson Teixeira Soares, Andrea Belone, Patrícia Sammarco Rosa, Maria Araci de Andrade Pontes, Heitor de Sá Gonçalves, Rossilene Cruz, Maria Lúcia Fernandes Penna, Deborah Ribeiro Carvalho, Vinicius Medeiros Fava, Samira Bührer-Sékula, Gerson Oliveira Penna, Claudia Maria Cabral Moro, Julio Cesar Nievola, Marcelo Távora Mira
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionLeprosy reactions (LR) are severe episodes of intense activation of the host inflammatory response of uncertain etiology, today the leading cause of permanent nerve damage in leprosy patients. Several genetic and non-genetic risk factors
Externí odkaz:
https://doaj.org/article/b26ff41f1e204a50b26f0dc2d27de53e
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/577c6c3055374244bdd577ecc17a3501
Autor:
Divya Khanna, Gilles de Wildt, Luiz Antonio Miranda de Souza Duarte Filho, Mitali Bajaj, Jo Freda Lai, Esme Gardiner, Andrea Maia Fernandes de Araújo Fonseca, Antje Lindenmeyer, Patrícia Sammarco Rosa
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-19 (2021)
Abstract Background Brazil has a high leprosy burden and poor treatment outcomes (TOs), manifesting in high relapse rates. Pernambuco, an impoverished Brazilian state suffering notable geographical health inequalities, has ‘hyperendemic’ leprosy.
Externí odkaz:
https://doaj.org/article/2f78692eb7bf4c26a0b253609a5104d3
Autor:
Fabiana Rodrigues Costa, Pedro Henrique Areco Gomes Moura, Sérgio da Rocha Alves-Júnior, Patricia Sammarco Rosa, Ivan Nunes
Publikováno v:
Papéis Avulsos de Zoologia, Vol 62 (2022)
Abstract Although communication capabilities are displayed by many vertebrate groups, some repertoires are poorly known, such as the case of xenarthrans, particularly armadillos, for which vocalization as a source of communicating to others remains p
Externí odkaz:
https://doaj.org/article/4996e783fb1748cdbadc2de0aa1c0a86
Autor:
Beatriz Junqueira de Souza, Mayara Abud Mendes, Gilberto Marcelo Sperandio da Silva, Patrícia Sammarco-Rosa, Milton Ozorio de Moraes, Marcia Rodrigues Jardim, Euzenir Nunes Sarno, Roberto Olmo Pinheiro, Bruno Siqueira Mietto
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Peripheral neuropathy is the main cause of physical disability in leprosy patients. Importantly, the extension and pattern of peripheral damage has been linked to how the host cell will respond against Mycobacterium leprae (M. leprae) infection, in p
Externí odkaz:
https://doaj.org/article/f9397b5d0cc94770bf5e5027431564dd
Autor:
André Alves Dias, Carlos Adriano de Matos e Silva, Camila Oliveira da Silva, Natasha Ribeiro Cardoso Linhares, João Pedro Sousa Santos, Aislan de Carvalho Vivarini, Maria Ângela de Mello Marques, Patrícia Sammarco Rosa, Ulisses Gazos Lopes, Márcia Berrêdo-Pinho, Maria Cristina Vidal Pessolani
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The respiratory tract is considered the main port of entry of Mycobacterium leprae, the causative agent of leprosy. However, the great majority of individuals exposed to the leprosy bacillus will never manifest the disease due to their capacity to de
Externí odkaz:
https://doaj.org/article/99a1b08cd85a430aa395dbf26bd9b92d