Zobrazeno 1 - 10
of 58
pro vyhledávání: '"P. STATHOPULOS"'
The spatial and spectral distributions of terahertz (THz) pulses emitted by two-color air plasmas are theoretically investigated for focused laser pulses and in the filamentation regime. We derive a so-called ''augmented'' conical emission model, whi
Externí odkaz:
http://arxiv.org/abs/2406.12643
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109699- (2024)
Summary: The mitochondrial calcium (Ca2+) uniporter (MCU) complex is regulated via integration of the MCU dominant negative beta subunit (MCUb), a low conductance paralog of the main MCU pore forming protein. The MCU amino (N)-terminal domain (NTD) a
Externí odkaz:
https://doaj.org/article/348c143208ee4c069cbc9ec6d8996af4
Autor:
Tailliez, C., Stathopulos, A., Skupin, S., Buožius, D., Babushkin, I., Vaičaitis, V., Bergé, L.
We study the influence of the polarization states of femtosecond two-color pulses ionizing gases on the emitted terahertz radiation. A local-current model and plane-wave evaluations justify the previously-reported impact on the THz energy yield and a
Externí odkaz:
http://arxiv.org/abs/2007.08191
Autor:
Travis R. Madaris, Manigandan Venkatesan, Soumya Maity, Miriam C. Stein, Neelanjan Vishnu, Mridula K. Venkateswaran, James G. Davis, Karthik Ramachandran, Sukanthathulse Uthayabalan, Cristel Allen, Ayodeji Osidele, Kristen Stanley, Nicholas P. Bigham, Terry M. Bakewell, Melanie Narkunan, Amy Le, Varsha Karanam, Kang Li, Aum Mhapankar, Luke Norton, Jean Ross, M. Imran Aslam, W. Brian Reeves, Brij B. Singh, Jeffrey Caplan, Justin J. Wilson, Peter B. Stathopulos, Joseph A. Baur, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112155- (2023)
Summary: The most abundant cellular divalent cations, Mg2+ (mM) and Ca2+ (nM-μM), antagonistically regulate divergent metabolic pathways with several orders of magnitude affinity preference, but the physiological significance of this competition rem
Externí odkaz:
https://doaj.org/article/324fd2ad3fb9463fa4701a04cb364947
Autor:
Sascha Kahlfuss, Ulrike Kaufmann, Axel R Concepcion, Lucile Noyer, Dimitrius Raphael, Martin Vaeth, Jun Yang, Priya Pancholi, Mate Maus, James Muller, Lina Kozhaya, Alireza Khodadadi‐Jamayran, Zhengxi Sun, Patrick Shaw, Derya Unutmaz, Peter B Stathopulos, Cori Feist, Scott B Cameron, Stuart E Turvey, Stefan Feske
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp 1-25 (2020)
Abstract Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca2+ influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca2+ channel ORAI1
Externí odkaz:
https://doaj.org/article/5dea67d69b0a4240ad6b7dfd0ac39c79
Autor:
Joshua J. Woods, Neeharika Nemani, Santhanam Shanmughapriya, Akshay Kumar, MengQi Zhang, Sarah R. Nathan, Manfred Thomas, Edmund Carvalho, Karthik Ramachandran, Subramanya Srikantan, Peter B. Stathopulos, Justin J. Wilson, Muniswamy Madesh
Publikováno v:
ACS Central Science, Vol 5, Iss 1, Pp 153-166 (2019)
Externí odkaz:
https://doaj.org/article/c11a3ac499984fe6bac920a1430a4843
Autor:
Neeharika Nemani, Edmund Carvalho, Dhanendra Tomar, Zhiwei Dong, Andrea Ketschek, Sarah L. Breves, Fabián Jaña, Alison M. Worth, Julie Heffler, Palaniappan Palaniappan, Aparna Tripathi, Ramasamy Subbiah, Massimo F. Riitano, Ajay Seelam, Thomas Manfred, Kie Itoh, Shuxia Meng, Hiromi Sesaki, William J. Craigen, Sudarsan Rajan, Santhanam Shanmughapriya, Jeffrey Caplan, Benjamin L. Prosser, Donald L. Gill, Peter B. Stathopulos, Gianluca Gallo, David C. Chan, Prashant Mishra, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1005-1019 (2018)
Summary: Mitochondria shape cytosolic calcium ([Ca2+]c) transients and utilize the mitochondrial Ca2+ ([Ca2+]m) in exchange for bioenergetics output. Conversely, dysregulated [Ca2+]c causes [Ca2+]m overload and induces permeability transition pore an
Externí odkaz:
https://doaj.org/article/d8a52722cb5c491eaab6dfcbe01c7e01
Autor:
Marc Fahrner, Michael Stadlbauer, Martin Muik, Petr Rathner, Peter Stathopulos, Mitsu Ikura, Norbert Müller, Christoph Romanin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Stormorken syndrome is associated with the R304W mutation in STIM1, which is a Calcium sensor in the endoplasmic reticulum. Here authors use FRET and electrophysiology to show that R304W induces STIM1 conformational extension by a dual mechanism resu
Externí odkaz:
https://doaj.org/article/f3d205c02ef7403b8fda99785e3df276
Autor:
Dhanendra Tomar, Zhiwei Dong, Santhanam Shanmughapriya, Diana A. Koch, Toby Thomas, Nicholas E. Hoffman, Shrishiv A. Timbalia, Samuel J. Goldman, Sarah L. Breves, Daniel P. Corbally, Neeharika Nemani, Joseph P. Fairweather, Allison R. Cutri, Xueqian Zhang, Jianliang Song, Fabián Jaña, Jianhe Huang, Carlos Barrero, Joseph E. Rabinowitz, Timothy S. Luongo, Sarah M. Schumacher, Michael E. Rockman, Alexander Dietrich, Salim Merali, Jeffrey Caplan, Peter Stathopulos, Rexford S. Ahima, Joseph Y. Cheung, Steven R. Houser, Walter J. Koch, Vickas Patel, Vishal M. Gohil, John W. Elrod, Sudarsan Rajan, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1673-1685 (2016)
Mitochondrial Ca2+ Uniporter (MCU)-dependent mitochondrial Ca2+ uptake is the primary mechanism for increasing matrix Ca2+ in most cell types. However, a limited understanding of the MCU complex assembly impedes the comprehension of the precise mecha
Externí odkaz:
https://doaj.org/article/824669f56e69431d8fcf04ba6cd6b4d4
Publikováno v:
New Journal of Physics, Vol 22, Iss 10, p 103038 (2020)
We study the influence of the polarization states of ionizing femtosecond two-color pulses on the emitted terahertz radiation in gases. A local-current model and plane-wave evaluations justify the previously-reported impact on the THz energy yield
Externí odkaz:
https://doaj.org/article/5d931c01d48b44589747a582dc85074d