Zobrazeno 1 - 10
of 71
pro vyhledávání: '"P. S. Dimitrov"'
Publikováno v:
Bulgarian Journal of Veterinary Medicine, Vol 24, Iss 2, Pp 229-238 (2021)
The effects of concomitant infection with chicken anaemia virus (CAV) on the incidence, clinical manifestation and mortality from leukosis, induced by the avian myelocytomatosis virus strain Mc29 were studied. Experimental one-day-old 15 I line White
Externí odkaz:
https://doaj.org/article/a835cb99d043401f98f32cf01b1bd119
Autor:
Guillem Pascual-Pasto, Brendan McIntyre, Margaret G. Hines, Anna M. Giudice, Laura Garcia-Gerique, Jennifer Hoffmann, Pamela Mishra, Stephanie Matlaga, Simona Lombardi, Rawan Shraim, Patrick M. Schürch, Mark Yarmarkovich, Ted J. Hofmann, Fatemeh Alikarami, Daniel Martinez, Matthew Tsang, Luis Gil-de-Gómez, Timothy T. Spear, Kathrin M. Bernt, Adam J. Wolpaw, Dimiter S. Dimitrov, Wei Li, Kristopher R. Bosse
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Novel chimeric antigen receptor (CAR) T-cell approaches are needed to improve therapeutic efficacy in solid tumors. High-risk neuroblastoma is an aggressive pediatric solid tumor that expresses cell-surface GPC2 and GD2 with a tumor microenv
Externí odkaz:
https://doaj.org/article/b2ad4e5f753a46548b7df6730192b457
Autor:
Yulu Wang, Yifang Sun, Zhaoling Shen, Cong Wang, Jun Qian, Qiyu Mao, Yajie Wang, Wenping Song, Yu Kong, Changyou Zhan, Zhenguo Chen, Dimiter S. Dimitrov, Zhenlin Yang, Shibo Jiang, Fan Wu, Lu Lu, Tianlei Ying, Lei Sun, Yanling Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Nipah virus infection, one of the top priority diseases recognized by the World Health Organization, underscores the urgent need to develop effective countermeasures against potential epidemics and pandemics. Here, we identify a fully human
Externí odkaz:
https://doaj.org/article/46eb885c817a4c7290a486dfc966cb8f
Autor:
Jiawei Zhang, Junjun Liu, Yali Yue, Lei Wang, Qunye He, Shuyi Xu, Junyan Li, Yunji Liao, Yu Chen, Shusheng Wang, Yueqing Xie, Baohong Zhang, Yanlin Bian, Dimiter S. Dimitrov, Yunsheng Yuan, Jianwei Zhu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Though tamoxifen achieves success in treating estrogen receptor α (ERα)-positive breast cancer, the followed development of tamoxifen resistance is a common challenge in clinic. Signals downstream of prolactin receptor (PRLR) co
Externí odkaz:
https://doaj.org/article/c25ae8cc70c544b79719f5ae53eeff5a
Autor:
Xiaojie Chu, Seungmin Shin, Du-San Baek, Liyong Zhang, Alex Conard, Megan Shi, Ye-Jin Kim, Cynthia Adams, Maggie Hines, Xianglei Liu, Chuan Chen, Zehua Sun, Dontcho V. Jelev, John W. Mellors, Dimiter S. Dimitrov, Wei Li
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Prostate stem cell antigen (PSCA) is expressed in all stages of prostate cancer, including in advanced androgen-independent tumors and bone metastasis. PSCA may associate with prostate carcinogenesis and lineage plasticity in prostate cancer. PSCA is
Externí odkaz:
https://doaj.org/article/1f085d6811ce4dcda8bde14f50a5302f
Autor:
Chuan Chen, Zehua Sun, Zening Wang, Seungmin Shin, Abigail Berrios, John W. Mellors, Dimiter S. Dimitrov, Wei Li
Publikováno v:
Antibodies, Vol 13, Iss 2, p 39 (2024)
The anaplastic lymphoma kinase (ALK, CD247) is a potential target for antibody-based therapy. However, no antibody-based therapeutics targeting ALK have entered clinical trials, necessitating the development of novel antibodies with unique therapeuti
Externí odkaz:
https://doaj.org/article/1841d17e6802452dac45208d88414a5b
Autor:
James W. Saville, Dhiraj Mannar, Xing Zhu, Shanti S. Srivastava, Alison M. Berezuk, Jean-Philippe Demers, Steven Zhou, Katharine S. Tuttle, Inna Sekirov, Andrew Kim, Wei Li, Dimiter S. Dimitrov, Sriram Subramaniam
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Saville, Mannar et al. provide a structural basis for enhanced antibody evasion and ACE2 binding by the Delta SARS-CoV-2 spike protein. They further identify a head-to-head dimer-of-trimers cryoEM reconstruction unique to the Kappa variant spike.
Externí odkaz:
https://doaj.org/article/feef3d51eb6145eeb9cb3f29799a3060
Autor:
S. Dimitrov, T. Dimitrova
Publikováno v:
Trakia Journal of Sciences, Vol 19, Iss 4, Pp 314-328 (2021)
Modern tourism is a complex socio-economic and cultural phenomenon of multifaceted significance. Apart from the traditional types of tourism, the modern (alternative, traditional) types of tourism are becoming more and more attractive. One of them
Externí odkaz:
https://doaj.org/article/9b9405b716e6467e8c08c9cc7546e5fe
Autor:
Thomas W. Geisbert, Kathryn Bobb, Viktoriya Borisevich, Joan B. Geisbert, Krystle N. Agans, Robert W. Cross, Abhishek N. Prasad, Karla A. Fenton, Hao Yu, Timothy R. Fouts, Christopher C. Broder, Antony S. Dimitrov
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Nipah and Hendra viruses are highly pathogenic bat-borne paramyxoviruses recently included in the WHO Blueprint priority diseases list. A fully registered horse anti-Hendra virus subunit vaccine has been in use in Australia since 2012. Based
Externí odkaz:
https://doaj.org/article/652276c0d46b42ed8977b0d8d12fab81
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Phage display is a well-established technology for in vitro selection of monoclonal antibodies (mAb), and more than 12 antibodies isolated from phage displayed libraries of different formats have been approved for therapy. We have constructed a large
Externí odkaz:
https://doaj.org/article/5403251b0c754604a2bcf9ddbf98c8ed