Zobrazeno 1 - 10
of 174
pro vyhledávání: '"P. Rouyer-Fessard"'
Autor:
Joseph Binet, Michel Gustave, Claudine Jondeau, Claire Marie, Mathilde Rouyer-Fessard, Adeline
Publikováno v:
Social Intervention / Intervenção Social; 2021, Issue 57/58, p369-407, 39p
Autor:
Etienne Régulier, Nicole Déglon, Yves Beuzard, E. Payen, P. Rouyer-Fessard, Patrick Aebischer, Bruno Dalle
Publikováno v:
Gene Therapy. 6:157-161
The goal of the present study was to analyze if sustained delivery of elevated doses of recombinant erythropoietin (Epo), by genetically modified and immunoprotected allogenic cells, was able to correct the chronic anemia, characteristic of a spontan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fffbd43b520c8b00ac380580310e4a
https://doi.org/10.1038/sj.gt.3300812
https://doi.org/10.1038/sj.gt.3300812
Publikováno v:
Hematology and Cell Therapy. 39:109-113
The erythropoietin (Epo) is a model of proteins expressed upon hypoxia, regulated at the transcriptional and post transcriptional levels. The Hypoxia Induced Factor (HIF-I) activates the transcription of genes which exhibit the Hypoxia Regulatory Ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10dc1cd683ba17fb334a6570e80f3049
https://doi.org/10.1007/s00282-997-0109-1
https://doi.org/10.1007/s00282-997-0109-1
Publikováno v:
Blood. 87:1188-1195
beta thalassemia (beta thal) in DBA/2J mice is a consequence of the spontaneous and complete deletion of the beta major globin gene. Homozygous beta thal mice have clinical and biological features similar to those observed in human beta thal intermed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d3b2a5a22424fb4edb721324295dc5
https://doi.org/10.1182/blood.v87.3.1188.bloodjournal8731188
https://doi.org/10.1182/blood.v87.3.1188.bloodjournal8731188
Publikováno v:
Hematology and cell therapy. 39(2)
The erythropoietin (Epo) is a model of proteins expressed upon hypoxia, regulated at the transcriptional and post transcriptional levels. The Hypoxia Induced Factor (HIF-I) activates the transcription of genes which exhibit the Hypoxia Regulatory Ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b4cada7cf7b334a1f23745a01486892
https://pubmed.ncbi.nlm.nih.gov/9229543
https://pubmed.ncbi.nlm.nih.gov/9229543
Publikováno v:
Blood. 87(3)
beta thalassemia (beta thal) in DBA/2J mice is a consequence of the spontaneous and complete deletion of the beta major globin gene. Homozygous beta thal mice have clinical and biological features similar to those observed in human beta thal intermed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eef57de67c75ae47b3b2e1193dfca1bb
https://pubmed.ncbi.nlm.nih.gov/8562946
https://pubmed.ncbi.nlm.nih.gov/8562946
Autor:
P Moullier, Nadia Naffakh, Jean Michel Heard, Olivier Danos, P Rouyer-Fessard, Y. Beuzard, Vainchenker W, N Blumenfeld, A. Henri, J L Villeval
Publikováno v:
Scopus-Elsevier
We have examined whether the secretion of erythropoietin (Epo) from genetically modified cells could represent an alternative to repeated injections of the recombinant hormone for treating chronic anemias responsive to Epo. Primary mouse skin fibrobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36b05b9654600d1178630feb226f7e2
https://europepmc.org/articles/PMC42132/
https://europepmc.org/articles/PMC42132/
Autor:
J L Guerquin-Kern, M.C. Garel, N Saadane, J Bardakdjian-Michau, A Pachnis, Paul-Henri Romeo, Y Blouquit, P Rouyer-Fessard, M Trudel, D Vidaud
Publikováno v:
The EMBO journal. 10(11)
In order to obtain a transgenic mouse model of sickle cell disease, we have synthesized a novel human beta-globin gene, beta SAD, designed to increase the polymerization of the transgenic human hemoglobin S (Hb S) in vivo. beta SAD (beta S-Antilles-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd4009e66c95b81db4aaa8e86446371
https://pubmed.ncbi.nlm.nih.gov/1915288
https://pubmed.ncbi.nlm.nih.gov/1915288
Akademický článek
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Publikováno v:
The Journal of biological chemistry. 265(29)
Altered membrane proteins have been previously described in beta thalassemia and are thought to play an important role in the shortened erythrocyte survival. To investigate the mechanism by which these changes occur, purified heme-containing alpha-he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d43b51af048eaedf2854daf7d209034
https://pubmed.ncbi.nlm.nih.gov/2211672
https://pubmed.ncbi.nlm.nih.gov/2211672