Výsledky vyhledávání - "P. Ronan O'Connell"

Akademický článek

Upper gastrointestinal bleeding due to Dieulafoy’s lesion of the stomach

Autor: Alsalt AL-Busaidi, Jaifar Alomairi, Omer Alabri, Eissa Alwheibi, Alazhar Almaghadari, Mhmod R. Kadom, P. Ronan O'Connell

Publikováno v: EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 862-866 (2023)

Dieulafoy’s lesion is a life-threatening and rare vascular malformation of the submucosal vessel that protrudes to the mucosa of the gastrointestinal tract. The vessel is abnormally dilated, and if it ruptures, it can cause severe acute gastrointes

Externí odkaz: https://doaj.org/article/2312f7b270ed463688ba0ad6f1dad614

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Akademický článek

Colonisation of the colonic mucus gel layer with butyrogenic and hydrogenotropic bacteria in health and ulcerative colitis

Autor: Helen Earley, Grainne Lennon, J. Calvin Coffey, Desmond C. Winter, P. Ronan O’Connell

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract Butyrate is the primary energy source for colonocytes and is essential for mucosal integrity and repair. Butyrate deficiency as a result of colonic dysbiosis is a putative factor in ulcerative colitis (UC). Commensal microbes are butyrogenic

Externí odkaz: https://doaj.org/article/66d0c141823f4f88bf3714160e19779c

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Akademický článek

The abundance of Akkermansia muciniphila and its relationship with sulphated colonic mucins in health and ulcerative colitis

Autor: Helen Earley, Grainne Lennon, Áine Balfe, J. Calvin Coffey, Desmond C. Winter, P. Ronan O’Connell

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)

Abstract Akkermansia muciniphila utilises colonic mucin as its substrate. Abundance is reduced in ulcerative colitis (UC), as is the relative proportion of sulphated mucin in the mucus gel layer (MGL). It is unknown if these phenomena are related, ho

Externí odkaz: https://doaj.org/article/5213841f65db421d829b47f1c74dd893

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Akademický článek

Efficacy and mechanism of sub-sensory sacral (optimised) neuromodulation in adults with faecal incontinence: study protocol for a randomised controlled trial

Autor: Eleanor McAlees, Paul F. Vollebregt, Natasha Stevens, Tom C. Dudding, Anton V. Emmanuel, Paul L. Furlong, Shaheen Hamdy, Richard L. Hooper, James F. X. Jones, Christine Norton, P. Ronan O’Connell, S. Mark Scott, Charles H. Knowles

Publikováno v: Trials, Vol 19, Iss 1, Pp 1-19 (2018)

Abstract Background Faecal incontinence (FI) is a substantial health problem with a prevalence of approximately 8% in community-dwelling populations. Sacral neuromodulation (SNM) is considered the first-line surgical treatment option in adults with F

Externí odkaz: https://doaj.org/article/b559781e144f4515a3463a1d3092052c

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The Relationship Between Cortical Activation in Response to Anorectal Stimuli and Continence Behavior in Freely Behaving Rats Before and After Application of Sacral Nerve Stimulation

Autor: Judith Evers, P. Ronan O’Connell, James F. X. Jones

Publikováno v: Diseases of the Colon & Rectum. 65:284-294

Changes in anorectal sensation have been reported in patients with fecal incontinence, and there is limited evidence that sacral nerve stimulation can restore normal sensation.The aims of the present study were to investigate changes in the transmiss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbd1278d2e294b6a2aa7ee54ca8f327
https://doi.org/10.1097/dcr.0000000000002038

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