Zobrazeno 1 - 10
of 25
pro vyhledávání: '"P. R. Zaman"'
Autor:
Elisa Zanini, Nicole Forster-Gross, Felix Bachmann, Adrian Brüngger, Paul McSheehy, Karine Litherland, Karin Burger, Anna C. Groner, Mila Roceri, Luc Bury, Martin Stieger, Nicole Willemsen-Seegers, Jos de Man, Diep Vu-Pham, Helma W. E. van Riel, Guido J. R. Zaman, Rogier C. Buijsman, Laurenz Kellenberger, Heidi A. Lane
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundThreonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1) are common essential kinases that collaborate in activating the spindle assembly checkpoint (SAC) at the kinetochore, ensuring appropriate chromosome alignment and segregation pr
Externí odkaz:
https://doaj.org/article/cf9a84a3e06f4b3a99f2975a86de17db
Autor:
Rene M. Bonifacio, Diana Jane Mari R. Zaman, Mayflor D. Prantilla-Arambala, Marlene S. Zarate
Publikováno v:
Ampersand, Vol 12, Iss , Pp 100152- (2024)
Externí odkaz:
https://doaj.org/article/2f4c531c18a84d788bf461592a0a09e7
Autor:
Gisele Nishiguchi, Lauren G. Mascibroda, Sarah M. Young, Elizabeth A. Caine, Sherif Abdelhamed, Jeffrey J. Kooijman, Darcie J. Miller, Sourav Das, Kevin McGowan, Anand Mayasundari, Zhe Shi, Juan M. Barajas, Ryan Hiltenbrand, Anup Aggarwal, Yunchao Chang, Vibhor Mishra, Shilpa Narina, Melvin Thomas, Allister J. Loughran, Ravi Kalathur, Kaiwen Yu, Suiping Zhou, Xusheng Wang, Anthony A. High, Junmin Peng, Shondra M. Pruett-Miller, Danette L. Daniels, Marjeta Urh, Anang A. Shelat, Charles G. Mullighan, Kristin M. Riching, Guido J. R. Zaman, Marcus Fischer, Jeffery M. Klco, Zoran Rankovic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Molecular-glue degraders are small molecules that induce a specific interaction between an E3 ligase and a target protein, resulting in the target proteolysis. The discovery of molecular glue degraders currently relies mostly on screening ap
Externí odkaz:
https://doaj.org/article/93a742dfa7284effac1e877a18d0d84e
Autor:
R.B. Kabir, R. Zaman, N.-E.-J. Tania, M. Asaduzzaman, A. Haque, F. Habib, N. Tanni, M. Nesa, A. Choudhury, M. Rahman, A. Sarker, K. Halder, N. Sharmin, M. Chowdhury, S. Nahar, S. Shahid, S. Shamsuzzaman
Publikováno v:
International Journal of Infectious Diseases, Vol 130, Iss , Pp S92-S93 (2023)
Intro: Nowadays, fresh fruits are popular sources of healthy diets with low energy density. Since they are consumed raw, it may act as a source of foodborne disease and a reservoir for antibiotic-resistant organisms. This study aimed to determine mic
Externí odkaz:
https://doaj.org/article/b035e2e7f40b42bf87f837545f7763d0
Autor:
Valentina Cordo’, Mariska T. Meijer, Rico Hagelaar, Richard R. de Goeij-de Haas, Vera M. Poort, Alex A. Henneman, Sander R. Piersma, Thang V. Pham, Koichi Oshima, Adolfo A. Ferrando, Guido J. R. Zaman, Connie R. Jimenez, Jules P. P. Meijerink
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
No targeted therapy has been approved yet for the treatment of T cell acute lymphoblastic leukemia. Here the authors show that unbiased phosphoproteomic profiling can identify targetable kinases and guide the design of personalized combination treatm
Externí odkaz:
https://doaj.org/article/c5d14de3e81a4a469e7a8481cdc98225
Autor:
Jeffrey J. Kooijman, Wilhelmina E. van Riel, Jelle Dylus, Martine B. W. Prinsen, Yvonne Grobben, Tessa J. J. de Bitter, Antoon M. van Doornmalen, Janneke J. T. M. Melis, Joost C. M. Uitdehaag, Yugo Narumi, Yusuke Kawase, Jeroen A. D. M. de Roos, Nicole Willemsen-Seegers, Guido J. R. Zaman
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer therapy. Although the number of approved kinase inhibitors increases rapidly, comprehensive in vitro profiling and comparison of inhibitor activities
Externí odkaz:
https://doaj.org/article/8a2b28555c90401aa5082f21d4b9f7f8
Publikováno v:
Brazilian Journal of Biology, Vol 81, Iss 2, Pp 474-483 (2020)
Abstract Nanoparticles are known bio elicitors in plant biotechnology. Different concentrations of ZnO, CuO and CoO nanoparticles were used for the enhanced accumulation of secondary metabolites and antioxidant activities in the callus derived from r
Externí odkaz:
https://doaj.org/article/db07ac47b930419da24b05b4f08248a4
Publikováno v:
Skin Health and Disease, Vol 1, Iss 4, Pp n/a-n/a (2021)
Abstract Background Adalimumab is an anti‐tumour necrosis factor administered for the management of severe psoriasis. Previously limited to Humira, new biosimilar medications have now emerged including Amgevita. To date, there have been no comparis
Externí odkaz:
https://doaj.org/article/8118a780452344d4b8f073e5a754a5b2
Publikováno v:
ACS Omega, Vol 5, Iss 3, Pp 1352-1362 (2020)
Externí odkaz:
https://doaj.org/article/c86f7fbd98664d628457a3350b3a304d
Publikováno v:
European Psychiatry, Vol 64, Pp S67-S67 (2021)
Abstract Body Carl Jung used the term, ‘The Wounded Healer’ as an archetypal dynamic to describe a phenomenon which may take place in the relationship between analyst and analysand. Jung discovered the Wounded Healer archetype in relation to hims
Externí odkaz:
https://doaj.org/article/dc55206275f740acb034b6e1aacf1224