Zobrazeno 1 - 10
of 106
pro vyhledávání: '"P. R. Wilkins"'
Autor:
Nina Deliu, Rajenki Das, Angelique May, Joseph Newman, Jo Steele, Melissa Duckworth, Rowena J. Jones, Martin R. Wilkins, Mark R. Toshner, Sofia S. Villar
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Pulmonary arterial hypertension is a life-threatening progressive disorder characterised by high blood pressure (hypertension) in the arteries of the lungs (pulmonary artery). Although treatable, there is no known cure for this ra
Externí odkaz:
https://doaj.org/article/48d3e973b36140abbd16fa6748b53598
Autor:
Sara Moufarrij, Roisin E. O'Cearbhaill, Qin Zhou, Alexia Iasonos, Simon Mantha, Jeffrey Zwicker, Cy R. Wilkins
Publikováno v:
Gynecologic Oncology Reports, Vol 53, Iss , Pp 101399- (2024)
Objective: Romiplostim is used to treat chemotherapy-induced thrombocytopenia in a variety of tumor types; however, few studies have examined its use in breast and gynecologic cancers. We evaluated platelet response and durability of response to romi
Externí odkaz:
https://doaj.org/article/e131afba54bb4d49ae70cf92ac5a58dc
Autor:
Chantal Kopecky, Michael Haug, Barbara Reischl, Nandan Deshpande, Bikash Manandhar, Thomas W. King, Victoria Lee, Marc R. Wilkins, Margaret Morris, Patsie Polly, Oliver Friedrich, Kerry‐Anne Rye, Blake J. Cochran
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 112-123 (2024)
Abstract Background Decreased insulin availability and high blood glucose levels, the hallmark features of poorly controlled diabetes, drive disease progression and are associated with decreased skeletal muscle mass. We have shown that mice with β
Externí odkaz:
https://doaj.org/article/c9be2adfa87a4331a6dbb7b63f6da60b
Autor:
Anna Ulrich, Yukyee Wu, Harmen Draisma, John Wharton, Emilia M. Swietlik, Inês Cebola, Eleni Vasilaki, Zhanna Balkhiyarova, Marjo-Riitta Jarvelin, Juha Auvinen, Karl-Heinz Herzig, J. Gerry Coghlan, James Lordan, Colin Church, Luke S. Howard, Joanna Pepke-Zaba, Mark Toshner, Stephen J. Wort, David G. Kiely, Robin Condliffe, Allan Lawrie, Stefan Gräf, Nicholas W. Morrell, Martin R. Wilkins, Inga Prokopenko, Christopher J. Rhodes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Pulmonary arterial hypertension (PAH) is characterised by pulmonary vascular remodelling causing premature death from right heart failure. Established DNA variants influence PAH risk, but susceptibility from epigenetic changes is unknown. We
Externí odkaz:
https://doaj.org/article/8e50277bf2c448aa930fb3478374f053
Autor:
P. G. Boorman, N. Torres-Albà, A. Annuar, S. Marchesi, R. W. Pfeifle, D. Stern, F. Civano, M. Baloković, J. Buchner, C. Ricci, D. M. Alexander, W. N. Brandt, M. Brightman, C. T. Chen, S. Creech, P. Gandhi, J. A. García, F. Harrison, R. Hickox, E. Kammoun, S. LaMassa, G. Lanzuisi, L. Marcotulli, K. Madsen, G. Matt, G. Matzeu, E. Nardini, J. M. Piotrowska, A. Pizzetti, S. Puccetti, D. Sicilian, R. Silver, D. J. Walton, D. R. Wilkins, X. Zhao, The HEX-P Collaboration
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 11 (2024)
Ever since the discovery of the first active galactic nuclei (AGN), substantial observational and theoretical effort has been invested into understanding how massive black holes have evolved across cosmic time. Circum-nuclear obscuration is now estab
Externí odkaz:
https://doaj.org/article/06e8a41e09e4449b99d01c68c15ce62e
Autor:
Allan Lawrie, Kelly Chin, Yiu‐Lian Fong, Cynthia Gargano, Xavier Gitton, Cheng He, David G. Kiely, Li Zhou, Lihan Zhou, Bradley A. Maron, Debbie Quinn, Stephan Rosenkranz, Dimitri Stamatiadis, Mark Toshner, Martin R. Wilkins, Luke Howard, Ioana R. Preston
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract A blood test identifying patients at increased risk of pulmonary hypertension (PH) could streamline the investigative pathway. The prospective, multicenter CIPHER study aimed to develop a microRNA‐based signature for detecting PH in breath
Externí odkaz:
https://doaj.org/article/b8ab45400a204fd294105f2eb5f0f631
Autor:
J. M. Piotrowska, J. A. García, D. J. Walton, R. S. Beckmann, D. Stern, D. R. Ballantyne, D. R. Wilkins, S. Bianchi, P. G. Boorman, J. Buchner, C.-T. Chen, P. Coppi, T. Dauser, A. C. Fabian, E. Kammoun, K. Madsen, L. Mallick, G. Matt, G. Matzeu, E. Nardini, A. Pizzetti, S. Puccetti, C. Ricci, F. Tombesi, N. Torres-Albà, K.-W. Wong
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 11 (2024)
Constraining the primary growth channel of supermassive black holes (SMBHs) remains one the most actively debated questions in the context of cosmological structure formation. Owing to the expected connection between SMBH spin parameter evolution and
Externí odkaz:
https://doaj.org/article/c254067cf45646e59c1e4ed6cdd384c6
Publikováno v:
Frontiers in Communication, Vol 9 (2024)
Improving science literacy is crucial amidst global challenges like climate change, emerging diseases, AI, and rampant disinformation. This is vital not only for future STEM generations but for all, to make informed decisions. Informal science commun
Externí odkaz:
https://doaj.org/article/dc38b77e1a39402db9db8f67a403dc9e
Autor:
Elham Alhathli, Thomas Julian, Zain Ul Abideen Girach, A. A. Roger Thompson, Christopher Rhodes, Stefan Gräf, Niamh Errington, Martin R. Wilkins, Allan Lawrie, Dennis Wang, Johnathan Cooper‐Knock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 6 (2024)
Background Pulmonary arterial hypertension (PAH) exhibits phenotypic heterogeneity and variable response to therapy. The metabolome has been implicated in the pathogenesis of PAH, but previous works have lacked power to implicate specific metabolites
Externí odkaz:
https://doaj.org/article/069b577d520045aca15df9ef83107b86
Autor:
Mit Shah, Marco H. de A. Inácio, Chang Lu, Pierre-Raphaël Schiratti, Sean L. Zheng, Adam Clement, Antonio de Marvao, Wenjia Bai, Andrew P. King, James S. Ware, Martin R. Wilkins, Johanna Mielke, Eren Elci, Ivan Kryukov, Kathryn A. McGurk, Christian Bender, Daniel F. Freitag, Declan P. O’Regan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cardiovascular ageing is a process that begins early in life and leads to a progressive change in structure and decline in function due to accumulated damage across diverse cell types, tissues and organs contributing to multi-morbidity. Dama
Externí odkaz:
https://doaj.org/article/5ca4f1d3a73b4fbe9ffa76bdd765cf9c