Zobrazeno 1 - 10
of 56
pro vyhledávání: '"P. R. Salvador"'
Autor:
P. R. Salvador, L. Pötter, M. G. Rocha, A. M. Fonseca Neto, M. B. Alves, M. J.O. Sichonany, A. P. Hundertmarck
Publikováno v:
Boletim de Indústria Animal, Vol 73, Iss 3, Pp 252-259 (2016)
The objective of this study was to evaluate the development of beef heifers exclusively fed alexander grass (Urochloa plantaginea (Link) Hitch) or alexander grass and whole rice meal as supplement offered from Monday to Friday. The experimental desig
Externí odkaz:
https://doaj.org/article/2570fd8d2ad649a28aff33b373d7b443
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Leukemia is a heterogeneous group of life‐threatening malignant disorders of the hematopoietic system. Immunotherapy, radiotherapy, stem cell transplantation, targeted therapy, and chemotherapy are among the approved leukemia treatments. U
Externí odkaz:
https://doaj.org/article/bf8c0c69d4d841d6a744bc6d0947a707
Autor:
Pedro M. P. Fernandes, Romina A. Guedes, Bruno L. Victor, Jorge A. R. Salvador, Rita C. Guedes
Publikováno v:
Frontiers in Chemistry, Vol 11 (2024)
Acquired resistance to drugs that modulate specific protein functions, such as the human proteasome, presents a significant challenge in targeted therapies. This underscores the importance of devising new methodologies to predict drug binding and pot
Externí odkaz:
https://doaj.org/article/4aaf6a3975db4b6990d7c0db939b27ba
Publikováno v:
BMC Palliative Care, Vol 21, Iss 1, Pp 1-11 (2022)
Abstract Purpose Despite that early integration of palliative care is recommended in advanced cancer patients, referrals to outpatient specialised palliative care (SPC) frequently occur late. Well-defined referral criteria are still missing. We analy
Externí odkaz:
https://doaj.org/article/e414282a0d3040789a9df64efbbb0386
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Cancer is a leading cause of mortality responsible for an estimated 10 million deaths worldwide in 2020, and its incidence has been rapidly growing over the last decades. Population growth and aging, as well as high systemic toxicity and chemoresista
Externí odkaz:
https://doaj.org/article/e46468c5b35b4d2c97b9e0b37488b68b
Autor:
Romina A. Guedes, Jorge H. Grilo, Andreia N. Carvalho, Pedro M. P. Fernandes, Ana S. Ressurreição, Vanessa Brito, Adriana O. Santos, Samuel Silvestre, Eleonora Gallerani, Maria João Gama, Riccardo Gavioli, Jorge A. R. Salvador, Rita C. Guedes
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1096 (2023)
Cancer is a complex multifactorial disease whose pathophysiology involves multiple metabolic pathways, including the ubiquitin–proteasome system, for which several proteasome inhibitors have already been approved for clinical use. However, the resi
Externí odkaz:
https://doaj.org/article/b023cf597f664b0180e81c7abc9a0029
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Ubiquitin-specific protease 7 (USP7) is a member of one of the most largely studied families of deubiquitylating enzymes. It plays a key role modulating the levels of multiple proteins, including tumor suppressors, transcription factors, epigenetic m
Externí odkaz:
https://doaj.org/article/1e4098dd5a274328b4057a564279e796
Autor:
Luís Costa, Luis Graca, Rita C. Acúrcio, Sabina Pozzi, Barbara Carreira, Marta Pojo, Nuria Gómez-Cebrián, Sandra Casimiro, Adelaide Fernandes, Andreia Barateiro, Vitor Farricha, Joaquim Brito, Ana Paula Leandro, Jorge A R Salvador, Leonor Puchades-Carrasco, Ronit Satchi-Fainaro, Rita C. Guedes, Helena F. Florindo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Inhibiting programmed cell death protein 1 (PD-1) or PD-ligand 1 (PD-L1) has shown exciting clinical outcomes in diverse human cancers. So far, only monoclonal antibodies are approved as PD-1/PD-L1 inhibitors. While significant clinical ou
Externí odkaz:
https://doaj.org/article/48b3a2c79c7342a9bccafeec9e0b33da
Autor:
C Avella-Garcia, R Salvador, D Paiva, A Martínez-Muelas, A Magariño, S Pérez, M Vergel, A Ayala, T Baena, J Gómez, M Sánchez
Publikováno v:
Psicosomática y Psiquiatría, Iss 15 (2021)
Externí odkaz:
https://doaj.org/article/76fff980fdeb461e969befb07c038c33
Autor:
CB Avella-Garcia, R Salvador, D Paiva, A Martinez-Muelas, A Magariño, S Pérez, M Vergel, A Ayala, T Baena, J Gómez, M Sánchez
Publikováno v:
Psicosomática y Psiquiatría, Iss 17 (2021)
Background: Health workers enduring the COVID-19 pandemic could be at risk of psychological stress. This study aimed to 1) measure the levels of perceived stress by workers at a psychiatric hospital in Barcelona, Spain, 2) to identify demographic or
Externí odkaz:
https://doaj.org/article/d99facde7a834509ba73c3bc61d35b9f