Zobrazeno 1 - 10
of 550
pro vyhledávání: '"P. R. Rowland"'
Autor:
Teressa M. Shaw, Devra Huey, Makky Mousa-Makky, Jared Compaleo, Kylie Nennig, Aadit P. Shah, Fei Jiang, Xueer Qiu, Devon Klipsic, Raymond R. R. Rowland, Igor I. Slukvin, Meagan E. Sullender, Megan T. Baldridge, Haichang Li, Cody J. Warren, Adam L. Bailey
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Arteriviruses infect a variety of mammalian hosts, but the receptors used by these viruses to enter cells are poorly understood. We identified the neonatal Fc receptor (FcRn) as an important pro-viral host factor via comparative genome-wide
Externí odkaz:
https://doaj.org/article/6e7bb8aedb52446288ced11b8dff371e
Reprogramming viral immune evasion for a rational design of next-generation vaccines for RNA viruses
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Type I interferons (IFNs-α/β) are antiviral cytokines that constitute the innate immunity of hosts to fight against viral infections. Recent studies, however, have revealed the pleiotropic functions of IFNs, in addition to their antiviral activitie
Externí odkaz:
https://doaj.org/article/57790c327b4d4365b69c564661bf5cd3
Autor:
Paula R. Chen, Raymond R. R. Rowland, Ana M. Stoian, Vlad Petrovan, Maureen Sheahan, Charan Ganta, Giselle Cino-Ozuna, Dae Young Kim, James M. Dunleavey, Kristin M. Whitworth, Melissa S. Samuel, Lee D. Spate, Raissa F. Cecil, Joshua A. Benne, Xingyu Yan, Ying Fang, Brad St. Croix, Kelly Lechtenberg, Kevin D. Wells, Randall S. Prather
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Senecavirus A (SVA) is a cause of vesicular disease in pigs, and infection rates are rising within the swine industry. Recently, anthrax toxin receptor 1 (ANTXR1) was revealed as the receptor for SVA in human cells. Herein, the role of ANTXR
Externí odkaz:
https://doaj.org/article/2a7f2ae4bfcc4e1b94db3d06a2d64dec
Autor:
Christian T. Stackhouse, Joshua C. Anderson, Zongliang Yue, Thanh Nguyen, Nicholas J. Eustace, Catherine P. Langford, Jelai Wang, James R. Rowland IV, Chuan Xing, Fady M. Mikhail, Xiangqin Cui, Hasan Alrefai, Ryan E. Bash, Kevin J. Lee, Eddy S. Yang, Anita B. Hjelmeland, C. Ryan Miller, Jake Y. Chen, G. Yancey Gillespie, Christopher D. Willey
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Key molecular regulators of acquired radiation resistance in recurrent glioblastoma (GBM) are largely unknown, with a dearth of accurate preclinical models. To address this, we generated 8 GBM patient-derived xenograft (PDX) models of acquired radiat
Externí odkaz:
https://doaj.org/article/f06e9a8597724e01bcfa17bb759ec86f
Autor:
Qian Dong, Joan K. Lunney, Kyu-Sang Lim, Yet Nguyen, Andrew S. Hess, Hamid Beiki, Raymond R. R. Rowland, Kristen Walker, James M. Reecy, Christopher K. Tuggle, Jack C. M. Dekkers
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-21 (2021)
Abstract Background Porcine reproductive and respiratory syndrome (PRRS) is a threat to pig production worldwide. Our objective was to understand mechanisms of persistence of PRRS virus (PRRSV) in tonsil. Transcriptome data from tonsil samples collec
Externí odkaz:
https://doaj.org/article/72186250470e43f3804021d4b3346867
Publikováno v:
Journal of Applied Poultry Research, Vol 28, Iss 4, Pp 1089-1098 (2019)
SUMMARY: Litter amendments are commonly used in commercial broiler production to improve litter quality and overall house conditions. While litter amendments used to limit the formation of gaseous ammonia have been studied extensively, there has been
Externí odkaz:
https://doaj.org/article/7a8b53397dec463a8703ab22fb8cbbeb
Autor:
Adeline N. Boettcher, A. Giselle Cino-Ozuna, Yash Solanki, Jayne E. Wiarda, Ellie Putz, Jeana L. Owens, Sara A. Crane, Amanda P. Ahrens, Crystal L. Loving, Joan. E. Cunnick, Raymond R. R. Rowland, Sara E. Charley, Jack C. M. Dekkers, Christopher K. Tuggle
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Severe combined immunodeficiency (SCID) is described as the lack of functional T and B cells. In some cases, mutant genes encoding proteins involved in the process of VDJ recombination retain partial activity and are classified as hypomorphs. Hypomor
Externí odkaz:
https://doaj.org/article/b63391f51010401c8662d80141e8c1cf
Autor:
Graham Lough, Andrew Hess, Melanie Hess, Hamed Rashidi, Oswald Matika, Joan K. Lunney, Raymond R. R. Rowland, Ilias Kyriazakis, Han A. Mulder, Jack C. M. Dekkers, Andrea Doeschl-Wilson
Publikováno v:
Genetics Selection Evolution, Vol 50, Iss 1, Pp 1-13 (2018)
Abstract Background High resistance (the ability of the host to reduce pathogen load) and tolerance (the ability to maintain high performance at a given pathogen load) are two desirable host traits for producing animals that are resilient to infectio
Externí odkaz:
https://doaj.org/article/c97999bf816344d791c43c9b6921ea40
Publikováno v:
Biogeosciences, Vol 15, Pp 973-985 (2018)
Tracking the sources of particulate organic matter (POM) exported from catchments is important to understand the transfer of energy from soils to oceans. The suitability of investigating the molecular composition of POM by thermally assisted hydr
Externí odkaz:
https://doaj.org/article/30a434470ea049b48c100c9bdf3a1607
Autor:
Emily H. Waide, Christopher K. Tuggle, Nick V. L. Serão, Martine Schroyen, Andrew Hess, Raymond R. R. Rowland, Joan K. Lunney, Graham Plastow, Jack C. M. Dekkers
Publikováno v:
Genetics Selection Evolution, Vol 50, Iss 1, Pp 1-12 (2018)
Abstract Background Genomic prediction of the pig’s response to the porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) would be a useful tool in the swine industry. This study investigated the accuracy of genomic prediction based on
Externí odkaz:
https://doaj.org/article/d233ec2141bc41e5a4478cf735c9db71