Zobrazeno 1 - 10
of 44
pro vyhledávání: '"P. R. Rapp"'
Autor:
Keenan A. Walker, Yang An, Abhay Moghekar, Ruin Moaddel, Michael R. Duggan, Zhongsheng Peng, Qu Tian, Luke C. Pilling, Shannon M. Drouin, Mark A. Espeland, Stephen R Rapp, Kathleen M Hayden, Aladdin H. Shadyab, Ramon Casanova, Madhav Thambisetty, Peter R. Rapp, Dimitrios Kapogiannis, Luigi Ferrucci, Susan M. Resnick
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Background Apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for late onset Alzheimer’s disease (AD). This case-cohort study used targeted plasma biomarkers and large-scale proteomics to examine the biological mechani
Externí odkaz:
https://doaj.org/article/ee7fd18cf0994326a5954b2b904a2e34
Autor:
Nada El Husseini, Christopher L. Schaich, Suzanne Craft, Stephen R. Rapp, Kathleen M. Hayden, Richey Sharrett, Mary Frances Cotch, Tien Y. Wong, Jose A. Luchsinger, Mark A. Espeland, Laura D. Baker, Alain G. Bertoni, Timothy M. Hughes
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Retinal vessel calibers share anatomic and physiologic characteristics with the cerebral vasculature and can be visualized noninvasively. In light of the known microvascular contributions to brain health and cognitive function, we aimed to d
Externí odkaz:
https://doaj.org/article/6bc37cff2dbf4539929a234764bc934d
Autor:
Jaclyn M. Martindale, Victor M. Ringheanu, Kelly A. Pring, Sandra Norona, Kimberly Wiseman, Roy E. Strowd, Leah Chapman, Joseph Rigdon, Stephen R. Rapp, Eric A. Storch, Edward Ip, Jonathan W. Mink
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
IntroductionPersistent Tic Disorders such as Tourette Syndrome are common neurodevelopmental disorders that are highly stigmatized. Many individuals with Persistent Tic Disorders experience peer rejection, loneliness, and self-stigma. Experiencing st
Externí odkaz:
https://doaj.org/article/31a29a1a32054690a0a011590b22c06b
Autor:
Marina Weiler, Kevin C. Stieger, Kavisha Shroff, Jessie P. Klein, William H. Wood, Yongqing Zhang, Prabha Chandrasekaran, Elin Lehrmann, Simonetta Camandola, Jeffrey M. Long, Mark P. Mattson, Kevin G. Becker, Peter R. Rapp
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
IntroductionTranscranial Magnetic Stimulation (TMS) is a noninvasive technique that uses pulsed magnetic fields to affect the physiology of the brain and central nervous system. Repetitive TMS (rTMS) has been used to study and treat several neurologi
Externí odkaz:
https://doaj.org/article/34f79dae29cb47b98cb8b8caed4990f0
Autor:
C'iana P. Cooper, Andrea T. Shafer, Nicole M. Armstrong, Yang An, Guray Erus, Christos Davatzikos, Luigi Ferrucci, Peter R. Rapp, Susan M. Resnick
Publikováno v:
NeuroImage, Vol 272, Iss , Pp 120048- (2023)
The cerebellum is involved in higher-order cognitive functions, e.g., learning and memory, and is susceptible to age-related atrophy. Yet, the cerebellum's role in age-related cognitive decline remains largely unknown. We investigated cross-sectional
Externí odkaz:
https://doaj.org/article/6d6f49654a754daf93f33c1b37e56604
Autor:
Marina Weiler, Perla Moreno-Castilla, Hannah M. Starnes, Edward L.R. Melendez, Kevin C. Stieger, Jeffrey M. Long, Peter R. Rapp
Publikováno v:
Brain Stimulation, Vol 14, Iss 5, Pp 1219-1225 (2021)
Background: Repetitive Transcranial Magnetic Stimulation (rTMS) has shown initial promise in combating age-related cognitive decline and dementia. The nature and severity of cognitive aging, however, varies markedly between individuals. Objective/hyp
Externí odkaz:
https://doaj.org/article/7c4d68af51f84f148944671ac43390db
Autor:
Luenda E. Charles, Desta Fekedulegn, Cecil M. Burchfiel, Kaori Fujishiro, Adina Zeki Al Hazzouri, Annette L. Fitzpatrick, Stephen R. Rapp
Publikováno v:
Safety and Health at Work, Vol 11, Iss 2, Pp 178-186 (2020)
Background: Cognitive impairment is a public health burden. Our objective was to investigate associations between work hours and cognitive function. Methods: Multi-Ethnic Study of Atherosclerosis (MESA) participants (n = 2,497; 50.7% men; age range 4
Externí odkaz:
https://doaj.org/article/bd0f8c4d2753466a809ad29b0d457d3b
Autor:
Diana Younan, Xinhui Wang, Joshua Millstein, Andrew J Petkus, Daniel P Beavers, Mark A Espeland, Helena C Chui, Susan M Resnick, Margaret Gatz, Joel D Kaufman, Gregory A Wellenius, Eric A Whitsel, JoAnn E Manson, Stephen R Rapp, Jiu-Chiuan Chen
Publikováno v:
PLoS Medicine, Vol 19, Iss 2, p e1003893 (2022)
BackgroundLate-life exposure to ambient air pollution is a modifiable risk factor for dementia, but epidemiological studies have shown inconsistent evidence for cognitive decline. Air quality (AQ) improvement has been associated with improved cardiop
Externí odkaz:
https://doaj.org/article/64c248c6b1cc4ef28013c7ad068bf88e
Autor:
Sasha Kravets, Rawan Allozi Rupnow, Abhishek Sethi, Mark A Espeland, Louis R Pasquale, Stephen R Rapp, Barbara E Klein, Stacy M Meuer, Mary N Haan, Pauline M Maki, Joelle A Hallak, Thasarat Sutabutr Vajaranant
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0258564 (2022)
PurposeTo investigate if accounting for a cup-to-disc ratio (CDR) genetic risk score (GRS) modified the association between large CDR and cognitive function among women.DesignThis was a retrospective study using data from the Women's Health Initiativ
Externí odkaz:
https://doaj.org/article/42c3b8f2887848fc85a75169e704a46e
Autor:
Longjian Liu, Kathleen M Hayden, PhD, Nathalie S May, MD, Bernhard Haring, MD, Zuolu Liu, MD, Victor W Henderson, ProfMD, Jiu-Chiuan Chen, MD, Edward J Gracely, PhD, Sylvia Wassertheil-Smoller, ProfPhD, Stephen R Rapp, ProfPhD
Publikováno v:
The Lancet. Healthy Longevity, Vol 3, Iss 1, Pp e42-e53 (2022)
Summary: Background: Whether blood pressure (BP), and at what level of controlled BP, reduces risk of cognitive impairment remains uncertain. We investigated the association of BP and hypertension treatment status with mild cognitive impairment and d
Externí odkaz:
https://doaj.org/article/9d17612208bd49e19b9f3e3995680987