Zobrazeno 1 - 10
of 49
pro vyhledávání: '"P. R. McHugh"'
Autor:
Joshua P. Heynen, Rebecca R. McHugh, Naveenjyote S. Boora, Gabrielle Simcock, Sue Kildea, Marie-Paule Austin, David P. Laplante, Suzanne King, Tony Montina, Gerlinde A. S. Metz
Publikováno v:
Metabolites, Vol 13, Iss 4, p 579 (2023)
Prenatal stress alters fetal programming, potentially predisposing the ensuing offspring to long-term adverse health outcomes. To gain insight into environmental influences on fetal development, this QF2011 study evaluated the urinary metabolomes of
Externí odkaz:
https://doaj.org/article/7eac4e552f154e88a6ec2d1977a45678
Autor:
Daniel R. McHugh, Elena Koumis, Paul Jacob, Jennifer Goldfarb, Michelle Schlaubitz-Garcia, Safae Bennani, Paul Regan, Prem Patel, Matthew J. Youngman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 5, Pp 1521-1539 (2020)
Aging is accompanied by a progressive decline in immune function termed “immunosenescence”. Deficient surveillance coupled with the impaired function of immune cells compromises host defense in older animals. The dynamic activity of regulatory mo
Externí odkaz:
https://doaj.org/article/1b1b8122f88f45659540a16a3de63e78
Autor:
Maureen A. Callanan, Claudia L. Castañeda, Graciela Solis, Megan R. Luce, Mathew Diep, Sam R. McHugh, Jennifer L. Martin, Judy Scotchmoor, Sara DeAngelis
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
Parent-child conversations in everyday interactions may set the stage for children's interest and understanding about science. Studies of family conversations in museums have found links to children's engagement and learning. Stories and narratives a
Externí odkaz:
https://doaj.org/article/9d49301f6d624a49a9259a5fd4d8ad1f
Autor:
Su-hua Wang, Nora Lang, George C. Bunch, Samantha Basch, Sam R. McHugh, Salvador Huitzilopochtli, Maureen Callanan
Publikováno v:
Frontiers in Education, Vol 6 (2021)
Despite decades of efforts, deficit narratives regarding language development and use by children and students from historically marginalized backgrounds remain persistent in the United States. Examining selective literature, we discuss the ideologie
Externí odkaz:
https://doaj.org/article/7089ba039ab7441a932f65a3fb8c3117
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 384-392 (2018)
Healthcare institutions may often prohibit “cold-calling” or direct contact with a potential research participant when the person initiating contact is unknown to the patient. This policy aims to maintain patient privacy, but may have unintended
Externí odkaz:
https://doaj.org/article/9151ef9ad403440db3a3d8bd4e058c2a
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 344 (2020)
Many heritable genetic disorders arise from nonsense mutations, which generate premature termination codons (PTCs) in transcribed mRNA. PTCs ablate protein synthesis by prematurely terminating the translation of mutant mRNA, as well as reducing mutan
Externí odkaz:
https://doaj.org/article/3c66c4831f71479da67c4795549cb042
Autor:
Daniel R McHugh, Miarasa S Steele, Dana M Valerio, Alexander Miron, Rachel J Mann, David F LePage, Ronald A Conlon, Calvin U Cotton, Mitchell L Drumm, Craig A Hodges
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199573 (2018)
Nonsense mutations are present in 10% of patients with CF, produce a premature termination codon in CFTR mRNA causing early termination of translation, and lead to lack of CFTR function. There are no currently available animal models which contain a
Externí odkaz:
https://doaj.org/article/77a623ef44c64c4d93965503e6c82613
Autor:
P. R. McHugh, D. A. Knoll
Publikováno v:
SIAM Journal on Scientific Computing. 19:291-301
We study the application of enhanced nonlinear iterative methods to the steady-state solution of a system of two-dimensional convection-diffusion-reaction partial differential equations that describe the partially ionized plasma flow in the boundary
Publikováno v:
Physics of Plasmas. 3:3358-3368
A combined edge plasma/Navier–Stokes neutral transport model is used to characterize divertor plasma detachment, in the collisional limit for neutrals, on a simplified two‐dimensional slab geometry with Alcator‐C‐MOD‐like plasma conditions
Publikováno v:
Contributions to Plasma Physics. 36:328-332
A combined edge plasma / Navier-Stokes neutral transport model is used to simulate dissipative divertor plasmas in the collisional limit for neutrals on a simplified two-dimensional slab geometry with ITER-like plasma conditions and scale lengths. Th