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pro vyhledávání: '"P. R. Lucek"'
Publikováno v:
Genetic epidemiology. 17
A recently developed approach that employs artificial neural networks (ANNs) was applied to the simulated data set to identify sets of marker loci involved in disease etiology. In this implementation, ANNs are trained to predict the disease state (ou
Autor:
P R, Lucek, J, Ott
Publikováno v:
Genetic epidemiology. 14(6)
Publikováno v:
American journal of medical genetics. 59(2)
In order to study genetic aspects in multicase families, 89 amyotrophic lateral sclerosis (ALS) and 214 Parkinson disease (PD) kindreds were analyzed in parallel studies. Obligate gene-carriers were identified as described previously [Chatkupt et al.
Publikováno v:
American journal of medical genetics. 44(4)
Fifty families (491 individuals in 137 sibships) with more than one living case of isolated, nonsyndromic spina bifida (SB) were analyzed genetically. There were twice as many gene-carrier females (56) as gene-carrier males (28) (P < 0.005). This was