Zobrazeno 1 - 8
of 8
pro vyhledávání: '"P. R. Hoban"'
Publikováno v:
Judgment and Decision Making, Vol 15, Pp 353-370 (2020)
Do people cheat more when they have something to gain, or when they have something to lose? The answer to this question isn’t straightforward, as research is mixed when it comes to understanding how unethical people will be when they might acquire
Externí odkaz:
https://doaj.org/article/541702e5c2d646b1ab1aaef8daa02ac5
Autor:
R. E. J. Howells, K. K. Dhar, P. R. Hoban, P. W. Jones, A. A. Fryer, C. W. E. Redman, R. C. Strange
Publikováno v:
International Journal of Gynecologic Cancer. 14:242-250
Ovarian cancer accounts for the majority of deaths from gynaecological malignancy, and polymorphisms in genes encoding the glutathione-S-transferase (GST) GSTP1 detoxifying enzymes may lead to variation in detoxification of carcinogens. We describe a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4514ab0c4624fe4c9ff28c9dc73b960
https://doi.org/10.1136/ijgc-00009577-200403000-00010
https://doi.org/10.1136/ijgc-00009577-200403000-00010
Publikováno v:
Allergy. 55:10-14
Susceptibility and outcome in complex disorders such as asthma and cancer appear to be determined, at least in part, by genetic polymorphism. However, while our ability to identify new allelic variants and study them in case and control populations h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a837062c4a37570a27365a810065788
https://doi.org/10.1034/j.1398-9995.2000.00501.x
https://doi.org/10.1034/j.1398-9995.2000.00501.x
Autor:
R C, Strange, N, El-Genidy, S, Ramachandran, T J, Lovatt, A A, Fryer, A G, Smith, J T, Lear, C, Wong, P W, Jones, F, Ichii-Jones, P R, Hoban
Publikováno v:
Annals of human genetics. 68(Pt 6)
Loss of function of the human patched gene (PTCH) is common and critical in basal cell carcinoma (BCC) development. Indirect evidence suggests polymorphism in PTCH mediates BCC risk. We studied 659 BCC cases and 300 controls to determine if exon 2(31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77e36d71a4bfc909951c8cedbb05a907
https://pubmed.ncbi.nlm.nih.gov/15598212
https://pubmed.ncbi.nlm.nih.gov/15598212
Publikováno v:
International journal of cancer. 95(5)
We investigated the expression of the cell cycle regulatory proteins cyclin D1 and p21(WAF1/CIP1) (p21) in human colorectal carcinomas using immunohistochemistry. Cyclin D1 was not detected in normal colonic epithelium; however, expression was observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c546d6219886df80033fbb3f4f064b4e
https://pubmed.ncbi.nlm.nih.gov/11494229
https://pubmed.ncbi.nlm.nih.gov/11494229
Autor:
N A, Hibberts, D J, Simpson, J E, Bicknell, J C, Broome, P R, Hoban, R N, Clayton, W E, Farrell
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(8)
Cyclin D1 plays an important role in the regulation of cell progression through G1 of the cell cycle and has been demonstrated to have oncogenic properties. Using RFLP-PCR, an A/G polymorphism within the cyclin D1 (CCND1) gene was analyzed in 151 spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51a3a59e7ca6758f39519d1e707b9244
https://pubmed.ncbi.nlm.nih.gov/10473097
https://pubmed.ncbi.nlm.nih.gov/10473097
Autor:
P R, Hoban, M I, Walton, C N, Robson, J, Godden, I J, Stratford, P, Workman, A L, Harris, I D, Hickson
Publikováno v:
Cancer research. 50(15)
Mitomycin C (MMC) is regarded as the prototype bioreductive alkylating agent in clinical use. To elucidate the biochemical basis of MMC resistance, we isolated a drug resistant derivative (designated CHO-MMC) of a Chinese hamster ovary cell line (CHO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5dae6b752081a537de294326a8c85e0
https://pubmed.ncbi.nlm.nih.gov/2114946
https://pubmed.ncbi.nlm.nih.gov/2114946
Publikováno v:
Cancer research. 47(6)
We have isolated a Chinese hamster ovary cell line, designated ADR-1, which exhibits hypersensitivity to a range of drugs which are thought to inhibit the action of the enzyme topoisomerase II. These include anthracyclines, other classes of intercala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f1bf80bb9151796c33640efa07d6656
https://pubmed.ncbi.nlm.nih.gov/2434220
https://pubmed.ncbi.nlm.nih.gov/2434220