Zobrazeno 1 - 10
of 30
pro vyhledávání: '"P. R. Hartig"'
Autor:
S P, Ho, P R, Hartig
Publikováno v:
Current opinion in molecular therapeutics. 1(3)
Although antisense oligonucleotides have been used in cell-based antisense experiments for nearly two decades, studies to investigate the function of CNS proteins in living animals were not successfully conducted until recently. Oligonucleotides are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d6025e71f6d4477d36f322a577ae0d0
https://pubmed.ncbi.nlm.nih.gov/11713799
https://pubmed.ncbi.nlm.nih.gov/11713799
Autor:
P. R. Hartig
Publikováno v:
Serotoninergic Neurons and 5-HT Receptors in the CNS ISBN: 9783540667155
Serotonin is an ancient neurotransmitter. Phylogenetic comparisons suggest that the earliest serotonin receptor may have first appeared over 700 million years ago (Peroutka and Howell 1994). It is released from fiber tracts originating in primitive b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fe5b88b91c314fe5df260c86db18398
https://doi.org/10.1007/978-3-642-60921-3_7
https://doi.org/10.1007/978-3-642-60921-3_7
Autor:
J M, Wetzel, J A, Salon, J A, Tamm, C, Forray, D, Craig, H, Nakanishi, W, Cui, P J, Vaysse, G, Chiu, R L, Weinshank, P R, Hartig, T A, Branchek, C, Gluchowski
Publikováno v:
Receptorschannels. 4(3)
A 3-dimensional model of the seven transmembrane helical segments (TMs) of the human alpha 1a-adrenoceptor was initially built by analogy to the known structure of bacteriorhodopsin. However, the rotational orientation of TM V about its helical axis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18374e29e2fb5f661d44fe3ff9b572e8
https://pubmed.ncbi.nlm.nih.gov/9014240
https://pubmed.ncbi.nlm.nih.gov/9014240
Autor:
D, Hoyer, D E, Clarke, J R, Fozard, P R, Hartig, G R, Martin, E J, Mylecharane, P R, Saxena, P P, Humphrey
Publikováno v:
Pharmacological reviews. 46(2)
It is evident that in the last decade or so, a vast amount of new information has become available concerning the various 5-HT receptor types and their characteristics. This derives from two main research approaches, operational pharmacology, using s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42a818e59931fbbc5b6ae19bdb1d5ac9
https://pubmed.ncbi.nlm.nih.gov/7938165
https://pubmed.ncbi.nlm.nih.gov/7938165
Autor:
C, Forray, J A, Bard, J M, Wetzel, G, Chiu, E, Shapiro, R, Tang, H, Lepor, P R, Hartig, R L, Weinshank, T A, Branchek
Publikováno v:
Molecular pharmacology. 45(4)
Molecular cloning studies have revealed the existence of three subtypes of alpha 1-adrenergic receptors. However, the link between any individual subtype and its functional role in the body has remained elusive. In an effort to bridge the gap between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc34122e0f6a63b0c1eddaa4754198b8
https://pubmed.ncbi.nlm.nih.gov/8183249
https://pubmed.ncbi.nlm.nih.gov/8183249
Autor:
P R, Hartig
Publikováno v:
EXS. 71
The serotonin system has long been thought to play a role at several steps in the cycle of alcohol abuse. Initial motivation may be triggered by anxiety, which may exhibit a serotonergic component (5-HT1A receptor). Alcohol can potentiate the opening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f66451bbebad491235a3e95b290bc793
https://pubmed.ncbi.nlm.nih.gov/7518266
https://pubmed.ncbi.nlm.nih.gov/7518266
Autor:
H.-T. Kao, N. Adham, Richard L. Weinshank, P. R. Hartig, L E Schechter, Theresa A. Branchek, M. Macchi, J M Zgombick
Publikováno v:
Clinical Pharmacology in Psychiatry ISBN: 9783642780127
The fact that nearly all known serotonin receptor subtypes are single subunit proteins, members of the same gene superfamily (the G protein-coupled receptor or 7TM superfamily) and that most are intronless genes has helped accelerate the cloning of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11246793ec3ea25d0ef93a557eb79d11
https://doi.org/10.1007/978-3-642-78010-3_3
https://doi.org/10.1007/978-3-642-78010-3_3
Autor:
P R, Hartig, N, Adham, J, Zgombick, M, Macchi, H T, Kao, L, Schechter, T, Branchek, R, Weinshank
Publikováno v:
Psychopharmacology series. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6d46ea59bad90d175fd45470a6bfe55
https://pubmed.ncbi.nlm.nih.gov/8361973
https://pubmed.ncbi.nlm.nih.gov/8361973
Autor:
P R, Hartig
Publikováno v:
NIDA research monograph. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f64a486e465c19b73006995340ce2fb
https://pubmed.ncbi.nlm.nih.gov/8289886
https://pubmed.ncbi.nlm.nih.gov/8289886
Publikováno v:
The Journal of biological chemistry. 267(29)
cDNA clones encoding two novel gamma-aminobutyric acid (GABA) transporters (designated GAT-2 and GAT-3) have been isolated from rat brain, and their functional properties have been examined in mammalian cells. The transporters display high affinity f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99d98f5c7463a8bf7c6cfbced9da2d67
https://pubmed.ncbi.nlm.nih.gov/1400419
https://pubmed.ncbi.nlm.nih.gov/1400419