Zobrazeno 1 - 10
of 490
pro vyhledávání: '"P. R. Grant"'
Autor:
Jason R. Grant, Emily K. Herman, Lael D. Barlow, Filippo Miglior, Flavio S. Schenkel, Christine F. Baes, Paul Stothard
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Structural variants (SVs) such as deletions, duplications, and insertions are known to contribute to phenotypic variation but remain challenging to identify and genotype. A more complete, accessible, and assessable collection of S
Externí odkaz:
https://doaj.org/article/2cdbfb1abf424d70a6dc1c15e4b1da55
Autor:
Ahmad N. Alzubaidi, Amy Zheng, Mohammad Said, Xuanjia Fan, Michael Maidaa, R. Grant Owens, Max Yudovich, Suraj Pursnani, R. Scott Owens, Thomas Stringer, Chad R. Tracy, Jay D. Raman
Publikováno v:
Current Oncology, Vol 31, Iss 8, Pp 4406-4413 (2024)
Background: MRI fusion prostate biopsy has improved the detection of clinically significant prostate cancer (CSC). Continued refinements in predicting the pre-biopsy probability of CSC are essential for optimal patient counseling. We investigated pot
Externí odkaz:
https://doaj.org/article/1b3c7258dad749e3ad58cea801eee206
Autor:
Jessica E Schwarz, Antonijo Mrčela, Nicholas F Lahens, Yongjun Li, Cynthia Hsu, Gregory R Grant, Carsten Skarke, Shirley L Zhang, Amita Sehgal
Publikováno v:
eLife, Vol 12 (2024)
Aging is associated with a number of physiologic changes including perturbed circadian rhythms; however, mechanisms by which rhythms are altered remain unknown. To test the idea that circulating factors mediate age-dependent changes in peripheral rhy
Externí odkaz:
https://doaj.org/article/127454988c634a1f8e230534ab8e4214
Autor:
Xueting Qiu, Lesley McGee, Laura L Hammitt, Lindsay R. Grant, Katherine L. O’Brien, William P. Hanage, Marc Lipsitch
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT After introducing pneumococcal conjugate vaccines (PCVs), serotype replacement occurred in Streptococcus pneumoniae. Predicting which pneumococcal strains will become common in carriage after vaccination can enhance vaccine design, public he
Externí odkaz:
https://doaj.org/article/e21b2fdcb52c46b4aaddb515700cc6a8
Autor:
Hannah G. Jones, Rodrigo R. N. Rizzo, Brian W. Pulling, Felicity A. Braithwaite, Ashley R. Grant, James H. McAuley, Mark P. Jensen, G. Lorimer Moseley, Amy Rees, Tasha R. Stanton
Publikováno v:
PAIN Reports, Vol 9, Iss 5, p e1185 (2024)
Abstract. Systematic reviews suggest that stand-alone hypnotic suggestions may improve pain outcomes compared with no treatment, waitlist, or usual care. However, in clinical practice, hypnosis is often provided adjunctively with other interventions,
Externí odkaz:
https://doaj.org/article/f4fd10130e424f08b5da88a9544d27aa
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Rising resistance to antimicrobials, particularly in the case of methicillin-resistant Staphylococcus aureus (MRSA), represents a formidable global health challenge. Consequently, it is imperative to develop new antimicrobial solu
Externí odkaz:
https://doaj.org/article/753b014ba3424044b1f37bd11750eb4b
Autor:
Taiga Miyazaki, Mark van der Linden, Katsuji Hirano, Takahiro Maeda, Shigeru Kohno, Elisa N. Gonzalez, Pingping Zhang, Raul E. Isturiz, Sharon L. Gray, Lindsay R. Grant, Michael W. Pride, Bradford D. Gessner, Luis Jodar, Adriano G. Arguedas
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Streptococcus pneumoniae is an important cause of community-acquired pneumonia (CAP) in Japan. Here, we report the serotype distribution and antimicrobial susceptibility of cultured pneumococcal isolates from Japanese adults aged ≥18 years with CAP
Externí odkaz:
https://doaj.org/article/bbe4a0860ea94ea9aff532951394f830
Autor:
Lindsay R. Grant, Kevin Apodaca, Lalitagauri Deshpande, John H. Kimbrough, Kyla Hayford, Qi Yan, Rodrigo Mendes, Alejandro Cané, Bradford D. Gessner, Adriano Arguedas
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
IntroductionPneumococcal conjugate vaccines (PCVs), including higher valency vaccines such as PCV20, have the potential to reduce pediatric otitis media. We assessed serotype distribution, potential PCV coverage, and antimicrobial susceptibility of S
Externí odkaz:
https://doaj.org/article/fe75c8964f5b4993bea3ea7db5e95ed8
Autor:
Fatima Khan, Yiyun Lin, Heba Ali, Lizhi Pang, Madeline Dunterman, Wen-Hao Hsu, Katie Frenis, R. Grant Rowe, Derek A. Wainwright, Kathleen McCortney, Leah K. Billingham, Jason Miska, Craig Horbinski, Maciej S. Lesniak, Peiwen Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Abundant macrophage infiltration and altered tumor metabolism are two key hallmarks of glioblastoma. By screening a cluster of metabolic small-molecule compounds, we show that inhibiting glioblastoma cell glycolysis impairs macrophage migrat
Externí odkaz:
https://doaj.org/article/35dfc6866f9b4dd6a0d5a41599612d47
Autor:
Richard J. Whittington, Thomas R. Grant, Jarrad McKercher, Monica Suann, Keith Hart, Kathrine A. Handasyde, James Macgregor, Mark E. Westman, Joanne H. Connolly
Publikováno v:
Animals, Vol 14, Iss 19, p 2834 (2024)
The platypus (Ornithorhynchus anatinus) is an amphibious, egg-laying mammal of high conservation value that is found only in Australia. The zoonotic bacterium Leptospira interrogans serovar Hardjo was discovered in platypuses in prior studies, but li
Externí odkaz:
https://doaj.org/article/afbd425e8f0c4271874a8a69e359030e